A kind of selective amination method of bacterial cellulose

Abstract

The invention relates to a selective amination method of bacterial cellulose and in particular relates to a bacterial cellulose selective amination method, which is to oxidize primary hydroxyl on C6 of anhydroglucose ring of the bacterial cellulose into carboxylic acid under an acidic condition by adopting a nitroxyl / enzyme co-oxidant system, and performing amination. The method comprises the following steps: (1) placing the lyophilized bacterial cellulose into the nitroxyl / enzyme system solution, regulating the pH to be acidic, slowly adding an oxidant, regulating the pH to be neutral, and cleaning to obtain selectively oxidized bacterial cellulose; and (2) placing the selectively oxidized bacterial cellulose into a diamine substance solution, heating to react for 2 to 4 hours, and washing to obtain the selectively aminated bacterial cellulose. According to the selective amination method of bacterial cellulose, the primary hydroxyl on C6 of the anhydroglucose ring of the bacterial cellulose can be selectively converted into amidogen completely and effectively, and can provide a chelation group to bacterial cellulose supported functional particles.

Description

technical field [0001] The invention relates to a selective amination method of bacterial cellulose, in particular to a method for the amination of the primary hydroxyl group at the C6 position of the anhydroglucose ring of bacterial cellulose, specifically a method using nitroxyl / enzyme co-oxidant The system oxidizes the primary hydroxyl group on the C6 position of the anhydroglucose ring of bacterial cellulose to carboxylic acid under acidic conditions, and then performs the selective amination method of bacterial cellulose for amination. Background technique [0002] Bacterial cellulose (BC for short) is a kind of cellulose produced by some bacteria. In order to distinguish it from the cellulose produced by plants, it is also called microbial cellulose. Bacterial cellulose is a new biological material with excellent performance, which has been extensively studied in recent years. Although the composition of bacterial cellulose is similar to general cellulose, its physica...

AI Technical Summary

Problems solved by technology

However, the force between the nanoparticle and the bacterial cellulose membrane prepared by forming a complex between the hydroxyl group and the metal ion is weak, and it is easy to slide off the surface of the membrane.

If a large number of nano-metal particles slip off the surface of the bacterial cellulose dressing and enter the human body along the wound, it will cause silver deposition and cause harm to the human body