Orally disintegrating tablets for treating functional dyspepsia

Abstract

The invention provides orally disintegrating tablets for treating functional dyspepsia, and the orally disintegrating tablets are prepared from gold thread extract, magnolia bark extract, acorus gramineus extract, processed pinellia tuber extract, baical skullcap root extract, dried tangerine peel extract, reed rhizome extract, oriental wormwood extract, raw coix extract, crosslinked polyvinylpyrrolidone used as a disintegrating agent, microcrystalline cellulose used as filler, magnesium stearate used as a lubricant and aspartame used as a flavoring agent. Patients suffering from spleen-stomach damp-heat syndrome functional dyspepsia are divided into a test group and a control group by adopting a multi-center random double-blind placebo control method, and 4 weeks are taken as a course of treatment. Results indicate that: the orally disintegrating tablets have excellent clinical curative effect to the functional dyspepsia spleen-stomach damp-heat syndrome, overcome the defects of the conventional Chinese medicinal preparation for treating the functional dyspepsia, and have safety and efficiency, low cost and convenient control.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to an orally disintegrating tablet for treating functional dyspepsia based on spleen-stomach damp-heat syndrome. Background technique [0002] Functional dyspepsia (FD) is a group of clinical syndromes with persistent or recurrent epigastric pain, postprandial fullness, abdominal distension, belching, early satiety, anorexia, nausea and other upper abdominal discomfort as the main symptoms , belongs to the category of functional gastrointestinal diseases. The reported prevalence rate in various countries is between 20% and 49%. In my country, patients with dyspepsia symptoms account for about 20% to 40% of digestive outpatient clinics. research hotspots. [0003] For functional dyspepsia, the dilemma faced by Western medicine is as follows: ①The pathogenesis has not been fully elucidated: it may involve many factors such as motility disorder, visceral sensitivity, infl...

AI Technical Summary

Problems solved by technology

②Lack of effective treatment, the disease is prone to relapse, consuming a lot of medical resources

At present, western medicine treatment is mainly to promote gastrointestinal motility, protect gastric mucosa and acid-suppressing traditional Chinese medicine. For those with psychological abnormalities, antidepressant and anxiety traditional Chinese medicine is far from satisfactory, and it is easy to repeat. There is a lack of individual treatment for multiple causes. Chemical diagnosis and treatment plan

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