Trinexapacethyl water dispersible granule preparation and preparation method thereof

Abstract

The invention discloses a trinexapacethyl water dispersible granule preparation, which consists of 10 to 30 percent of trinexapacethyl raw medicine, 1 to 10 percent of wetting agents, 1 to 15 percent of dispersing agents, 1 to 10 percent of disintegrating agents, 30 to 60 percent of absorbing agents and 1 to 50 percent of inert carriers. The trinexapacethyl water dispersible granule preparation is produced by adopting a circular disc granulation mode, the kneading and the granulation are integrated into one step, and work procedures are reduced. Obtained products are spherical granules, the appearance is attractive, the flowability is good, the disintegration is fast, the heat generation is avoided in the granulation process, and the method is suitable for the production of low-melting-point raw medicine.

Description

Technical field

[0001] The invention relates to a trinexapac-ethyl water dispersible granule and a preparation method thereof. Background technique

[0002] Triflux-ethyl is a cyclohexane carboxylic acid plant growth regulator, which regulates plant growth by inhibiting the biosynthesis of gibberellin. Used in cereal crops and winter rape, it can prevent lodging and improve harvest efficiency; used in lawns can reduce the number of trimmings; used in sugarcane can promote maturity. Due to the low melting point of trinexapac-ethyl, which is only 36°C, the current main dosage forms are emulsifiable concentrates and microemulsions, and no water-dispersible granules are available. Emulsifiable concentrates use a large number of environmentally toxic solvents containing benzene rings, and microemulsions also contain more polar solvents that are not easily degradable and a large number of polymer emulsifiers, which are more harmful to the environment and human body.

[0003] In accorda...

Images