Preparation method of N<1>-(2-aminoethyl)ethane-1,2-diamine
An ethylenediamine and aminoethyl technology, which is applied in the preparation of amino compounds, the preparation of organic compounds, chemical instruments and methods, etc., can solve the problems of unstable composition of the reaction solution, reduced catalyst activity, difficult product separation, etc. Production of piperazine and some other high boilers, inhibition of polymerization and decomposition phenomena, and the effect of simple subsequent separation
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Embodiment 1
[0031] Use the styrene-divinylbenzene strongly basic anion exchange resin after 0.6g transformation and the X-type molecular sieve that 60g has been processed with potassium nitrate, and 20g amorphous cobalt catalyst, its cobalt content is 97.5% (weight), will 60g of commercially available iminodiacetonitrile, 400ml of methanol, 12.0ml of 0.1wt% concentration of potassium hydroxide in methanol are mixed and put into a 1L stainless steel autoclave; 300 rev / min) and heated to 90°C. At this time, the system pressure is 8.0Mpa, and the hydrogen gas is passed to 14Mpa, and the pressure is maintained until there is no obvious absorption of hydrogen gas (about 5 hours). Stand to cool to room temperature, open the exhaust valve to release the pressure to 2-3Mpa, collect the reaction liquid from the liquid discharge port, it is a colorless transparent liquid, and analyze and measure it by GC (the normalized result after deducting the solvent and auxiliary agent, the following Same), im...
Embodiment 2
[0033] Use the styrene-divinylbenzene strongly basic anion exchange resin after 50g transformation and the Y type molecular sieve that 10g handles with cesium acetate, and the catalyzer (its cobalt content is 27.5%, weight) of 20g diatomite load, with 50g Iminodiacetonitrile, 400ml of methanol, and 2.2ml of 40% potassium hydroxide aqueous solution are mixed and placed in a stainless steel high-pressure reactor with a volume of 1L. After nitrogen replacement, 300g of liquid ammonia is added, heated and stirred, and hydrogen is charged to maintain the reaction. The temperature was 100°C and the pressure was 16Mpa. After the reaction was complete, the reaction liquid was collected. GC analysis showed that the conversion rate of IDAN was 99.04%, the selectivity of DETA was 85.52%, and the selectivity of piperazine was 13.17%.
Embodiment 3
[0035] Use the acrylic acid basic anion exchange resin after 12g conversion and 0.3g with the Y-type molecular sieve of cesium acetate process and 0.64g ruthenium / carbon catalyst, its ruthenium content is 0.5% (weight), with 60g iminodiacetonitrile and 400ml ethanol and After mixing, put it into a stainless steel high-pressure reactor with a volume of 1L, and then add 7.6ml of 5% potassium hydroxide ethanol solution. After nitrogen replacement, add 34g of liquid ammonia, heat and stir, and fill with hydrogen to maintain the reaction temperature. The temperature was 90°C, the pressure was 10Mpa, after the reaction was complete, the reaction liquid was collected, and the GC analysis showed that the conversion rate of IDAN was 100%, the selectivity of DETA was 91.73%, and the selectivity of piperazine was 6.93%.
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