Isoleucine fermenting process

Abstract

The invention relates to an isoleucine fermenting process. The key points are that: the isoleucine fermenting process comprises the following steps of: (1) culturing strains; (2) fermenting; (3) separating fermenting solution; (4) carrying out ion exchange in clear liquid of the fermenting solution; and (5) evaporating and crystallizing. According to the process provided by the invention, better fermenting index is generated; the yield of a metabolic product of isoleucine is increased, and the acid production rate is averagely increased by 0.48 percentage point in comparison with that before innovation; the conversion rate of the metabolic product of isoleucine is increased, and the sugar-acid conversion rate is increased by 3.2 percentage point; the generated strains can realize rapid growth and metabolism, the fermenting cycle is shortened by 4-6 h, the turnover rate of equipment is increased, and the yield is increased correspondingly; and metabolic by-products are reduced, the purity of metabolic products in corresponding fermenting solution is improved correspondingly, the process is favorable for extracting operation of products and purity of products, and the fermenting and extracting costs are reduced at the same time.

Description

technical field [0001] The invention relates to the technical field of amino acid production, in particular to a fermentation process for isoleucine in branched-chain amino acids. Background technique [0002] my country's amino acid production industry is a growing industry, mainly glutamic acid and lysine. Branched-chain amino acids—such as isoleucine, valine and other industries developed relatively late, with a low start and backward technology, and there has been an imbalance in the development of the amino acid industry, and the supply of some amino acids exceeds the demand. The production cost of branched-chain amino acids cannot be reduced, and the quality of the products is poor, and the price cannot go up. Most of the branched-chain amino acids produced cannot be used in the production of feed, and the quality cannot reach the pharmaceutical grade. Many domestic amino acid factories are in urgent need of high-quality amino acids. High-quality, low-cost production ...

AI Technical Summary

Problems solved by technology

[0007] (4) As far as the amino acid industry is concerned, the pollution control is not enough, and there is still a certain distance from the national requirements, and the environmental protection task is quite heavy and arduous

[0011] (2) Less investment in research and development, fewer varieties, poor adaptability and anti-risk ability, which affect the independent innovation of the enterprise and the improvement of the technical level, resulting in insufficient stamina for the development of the enterprise;

[0012] (3) The environmental protection management is not thorough, and the overall clean production level of the industry is not high;

[0013] (4) The level of modern management and product quality management is low, and phenomena such as production fluctuations, bacterial contamination, high yields and poor harvests occur from time to time, which affect the improvement of profitability;

[0014] (5) The low level of serialization and automation affects the improvement of tooling and modern management;

[0015] (6) Intensified competition, less collaboration and communication, unbalanced technical level among enterprises, and widening gap

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