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High-activity probiotic composition suitable for infants and preparation method thereof

A technology for probiotics and infants, which is applied in the field of highly active probiotic compositions and their preparation, can solve the problems of translocation of flora, higher requirements for the use of probiotics, damage to the growth conditions of beneficial bacteria, etc., and meets the requirements of temperature and humidity Strict, gut health-boosting, immune-boosting effects

Active Publication Date: 2012-06-27
杭州千岛湖康诺邦健康产品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, infants and young children are still developing, and their intestines are still very fragile. If the amount of probiotics supplemented is too large, it may irritate the stomach. Although the antibacterial substances produced by probiotics (such as lactic acid bacteria) can inhibit and eliminate many pathogenic microorganisms, but At the same time, it also destroys the growth conditions of beneficial bacteria to the human body, which will affect the baby's normal digestive function, especially for infants with gastroenteritis and premature infants; on the other hand, too much "beneficial bacteria" may theoretically cause Microbiota translocation; there is currently no evidence that high doses of probiotics in infants and young children are beneficial
[0008] Therefore, as a special group of infants, they have higher requirements for the use of probiotics. Unsuitable strains and unsuitable excipients are not conducive to the growth and development of infants.
Improper use of probiotics is not only useless but also harmful

Method used

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  • High-activity probiotic composition suitable for infants and preparation method thereof
  • High-activity probiotic composition suitable for infants and preparation method thereof
  • High-activity probiotic composition suitable for infants and preparation method thereof

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preparation example Construction

[0046] Such as figure 1 Shown preparation process, preparation method of the present invention is:

[0047] ① All the excipients need to be dried until the water content is ≤1.5%, and the water activity (Aw) is ≤0.1;

[0048] ② After the probiotics are taken out from the cold storage, return to the temperature at low temperature (≤18°C) for 10 hours;

[0049] ③The temperature in the mixing room is controlled at ≤18°C, and the relative humidity (RH) is ≤35%;

[0050] ④ Replace the air in the mixer with dry medical nitrogen;

[0051] ⑤ Add a small amount of maltodextrin (5 times the amount of probiotics), then add probiotics, mix for 5 minutes, then add the remaining maltodextrin and the remaining raw and auxiliary materials, mix for 20 minutes, and wait for discharge;

[0052] ⑥ Replace the air in the container with dry nitrogen and fill it, and store it in a sealed container, or pack it in vacuum.

[0053]⑦ During the packing process, fill the hopper with nitrogen gas, and...

Embodiment 1

[0055] Embodiment 1: solid beverage

[0056] Bifidobacterium lactis BI-071kg, Bifidobacterium lactis HN019 1.3kg, Bifidobacterium animalis Bb-12 1kg, maltodextrin 60kg, glucose 20kg, whey powder 11.7kg, galacto-oligosaccharide 5kg.

[0057] The preparation method and process requirements, the process is as follows figure 1 Shown:

[0058] The first step: raw material pretreatment

[0059] 1. Lactobacillus acidophilus and Bifidobacterium lactis need to be stored in the freezer and warmed up at 15±5°C for 10 hours before production;

[0060] 2. Raw materials with larger particles need to pass through a 40-mesh sieve;

[0061] 3. Raw materials with high water activity need to be dried to make the water activity (Aw) ≤ 0.1;

[0062] Step Two: Production Requirements

[0063] 1. Workshop requirements: temperature ≤ 18 ℃, humidity ≤ 35%;

[0064] Step Three: Mixing

[0065] First replace the air in the mixer with dry medical nitrogen, put in a small amount of pretreated malto...

Embodiment 2

[0071] Embodiment 2: tablet

[0072] Bifidobacterium lactis BI-07 0.5kg, Bifidobacterium animalis Bb-12 0.5kg, Lactobacillus acidophilus NCFM 0.5kg, maltodextrin 45kg, glucose 20kg, whey powder 20kg, fructooligosaccharide 10kg, magnesium stearate 3.5kg, appropriate amount of adhesive.

[0073] Preparation method and process requirements:

[0074] Maltodextrin, glucose, whey powder, and fructooligosaccharides were mixed, granulated and dried to a water activity (Aw)≤0.1, mixed according to the mixing method in Example 1, and tableted. Made with probiotics 4*10 9 cfu / g tablet, the daily dosage for infants aged 1-3 is 1-2g.

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Abstract

The invention relates to a high-activity probiotic composition suitable for infants and a preparation method thereof. The composition contains the following active components of: by weight, 0.33-3.3% of bifidobacteria, 45-60% of maltodextrin, 10-20% of glucose, 10-20% of whey powder and 5-10% of prebiotics. The preparation method comprises the following steps of: (1) drying the auxiliary materials until water activity (Aw) is less than or equal to 0.1; (2) replacing the air in a mixer with dry medical nitrogen; and (3) adding a few maltodextrin, adding probiotics, mixing for 5 minutes, adding residual maltodextrin and other raw and auxiliary materials, uniformly mixing, and discharging. The composition provided by the invention and functional foods (including health products) prepared by the composition have advantages of high safety of the probiotic strains and raw and auxiliary materials, balanced combination and appropriate bacteria number, are more suitable for Chinese infants' intestinal tracts, and have effects of enhancing infant's immunity and promoting the health of intestinal tract.

Description

technical field [0001] The invention relates to a functional food (including health food), more specifically, a highly active probiotic composition suitable for infants and young children and a preparation method thereof. Background technique [0002] There are many bacteria in the "gut" of the human body, some of which are beneficial to human health, and some are harmful to human health. We are accustomed to calling the beneficial and harmless bacteria in the normal intestinal flora as probiotics, which can regulate the balance of intestinal flora and maintain the health of the intestinal tract. Common probiotics include bifidobacteria, lactobacilli, enterococci, and yeasts. Under normal circumstances, "beneficial bacteria" and "harmful bacteria" are in a state of balance, co-existing with mutual restriction and interdependence. Once the balance is broken, corresponding diseases will appear. [0003] The functions of probiotics mainly include: inhibiting the reproduction...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/09
Inventor 吴芝岳邵胜荣孙俊蔡彦胡钢
Owner 杭州千岛湖康诺邦健康产品有限公司
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