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Ointment for treating gynaopathy and dermatoses and preparation method thereof

A technology for skin diseases and gynecological diseases, which is applied in skin diseases, ointment delivery, medical preparations containing active ingredients, etc. accepted effect

Inactive Publication Date: 2013-06-12
李怀珠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The curative effect of current medicines for vaginitis is not exact, and the cure rate is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Formula: 13g of halcinonide ointment (containing 10mg of halcinonide per 10g), 40g of menthol, 30g of camphor, 7g of disodium edetate, 80g of polyethylene glycol monostearate, 30 parts of purified water.

[0056] Preparation process: heat polyethylene glycol monostearate in a water bath to about 60°C to melt, and set aside; under stirring, add disodium edetate to water to dissolve, add to the above polyethylene glycol monostearate In fatty acid ester, mix well, make ointment matrix; Put menthol, camphor in mortar and grind and co-melt, then mix with the above-mentioned matrix cooled to below 45 ℃, finally add halcinonide ointment, mix well, Get 200g of ointment, pack it separately, and get it.

Embodiment 2

[0058] Formula: halcinonide ointment (10mg per 10g containing halcinonide) 13g, menthol 40g, camphor 40g, edetate disodium 7g, polyethylene glycol monostearate 40g, essence 3g, carbomer 4g, Sodium bicarbonate 3g, purified water 50g.

[0059] Preparation process: heat polyethylene glycol monostearate in a water bath to about 60°C to melt, and set aside; under stirring, disperse carbomer in water, add sodium bicarbonate, mix well, and add edetic acid Add disodium to the dispersion system to dissolve, add to the above-mentioned polyethylene glycol monostearate, and mix well to obtain an ointment base; put menthol and camphor in a mortar, grind and co-melt, and then cool to 45 Mix the above-mentioned bases below ℃, and finally add halcinonide ointment and essence, mix well to get 200g of ointment, pack it separately, and get it.

Embodiment 3

[0061] Formula: Halcinonide cream (10mg per 10g) 12g, menthol 30g, camphor 30g, edetate disodium 6g, polyethylene glycol monostearate 40g, essence 1.5g, carbomer 1g, 0.5g of sodium bicarbonate, 40g of purified water.

[0062] Preparation process: heat polyethylene glycol monostearate in a water bath to about 60°C to melt, and set aside; under stirring, disperse carbomer in water, add sodium bicarbonate, mix well, and add edetic acid Add disodium to the dispersion system to dissolve, add to the above-mentioned polyethylene glycol monostearate, and mix well to obtain an ointment base; put menthol and camphor in a mortar, grind and co-melt, and then cool to 45 Mix the above-mentioned bases below ℃, and finally add halcinonide cream and essence, mix evenly to obtain 160 g of ointment, which is packaged separately.

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PUM

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Abstract

The invention discloses an ointment for treating gynaopathy and dermatoses and a preparation method thereof. The externally-applied ointment is prepared from halcinonide preparation, menthol crystal and camphor which are utilized as raw materials according to a certain preparation technology, and is prepared from the following raw materials in parts by weight: 6 to 6.5 parts of halcinonide preparation, 15 to 20 parts of menthol crystal, 15 to 20 parts of camphor, 3 to 3.5 parts of edetate disodium, 20 to 40 parts of polyethylene glycol mono stearate, 0 to 3 parts of essence, 0 to 2 parts of carbomer, 0 to 2 parts of sodium bicarbonate and 15 to 25 parts of pure water. The externally-applied ointment is low in cost, has the effects of clearing away heat, eliminating dampness, dispelling the wind, killing worms, diminishing inflammation and relieving itching, has better treatment effects, has the characteristics of being easy to prepare, lower in cost and obvious in treatment effect, and can be used for treating the gynaopathy, such as vaginitis, cervicitis and cervical erosion, caused by various germs, and treating the dermatoses, such as tinea corporis, tinea cruris, tinea of feetand hands and various dermatitis, caused by various fungus infection. The externally-applied ointment has exact treatment effects, takes effect rapidly, is low in cost and convenient to use, and has no toxic and side effects, thus being worthy of popularization and application.

Description

technical field [0001] The invention relates to a medicine for treating gynecological diseases and skin diseases and a preparation method thereof, in particular to an ointment for treating gynecological diseases and skin diseases and a preparation method thereof. Background technique [0002] Diseases caused by fungi are collectively referred to as "fungal diseases". Among them, dermatophytosis has the highest incidence rate and can occur in various parts of the body, such as perineum, hands, and feet. Dermatomycosis is commonly called as " ringworm ", is a kind of contagious skin disease that fungus causes, and common dermatophytosis has athlete's foot, tinea manuum, tinea corporis, jock itch etc. But, up to the present, the curative effect of the medicine of various treatment because of the dermatosis that fungus infection causes is all not very exact, and some medicine also has toxic side effect, stimulates human skin. [0003] Cervical erosion is a frequently-occurring ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/58A61K36/534A61K36/54A61K9/06A61P15/00A61P17/00A61P15/02A61P31/00A61P31/10A61P29/00A61P33/02A61K31/125A61K31/045
Inventor 李怀珠
Owner 李怀珠
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