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Method for detecting sulfur dioxide residue limit of traditional Chinese medicinal material or traditional Chinese medicinal decoction tablet

A technology of decoction pieces of traditional Chinese medicine and sulfur dioxide, which is applied in the direction of analysis using chemical indicators, can solve the problems of complex operation, expensive equipment, and complicated equipment, and achieve the effects of cheap and easy-to-obtain equipment, short reaction time, and easy operation

Active Publication Date: 2012-10-17
广西众森中药制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although this method is more accurate in quantification, the device is more complicated, the price is higher, the chemical reagents used in the experiment are more, and nitrogen gas needs to be filled at the same time, the operation is more complicated, and the result needs to be converted by counting, which is not conducive to the General promotion of rapid detection methods in non-professional fields
With the continuous emergence and development of new methods and technologies in analytical science, new rapid detection technologies for sulfur dioxide residues, such as various sensors, have developed rapidly. However, many of the new rapid detection technologies are expensive and difficult to popularize.

Method used

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  • Method for detecting sulfur dioxide residue limit of traditional Chinese medicinal material or traditional Chinese medicinal decoction tablet
  • Method for detecting sulfur dioxide residue limit of traditional Chinese medicinal material or traditional Chinese medicinal decoction tablet
  • Method for detecting sulfur dioxide residue limit of traditional Chinese medicinal material or traditional Chinese medicinal decoction tablet

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Experimental program
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Effect test

Embodiment 1

[0052] Embodiment 1 The equipment used in the detection method of the present invention

[0053] Such as figure 1 As shown, the equipment includes a conical flask 1, an airway 2, a cock 3, and a cock cover 4, wherein the airway 2 is connected to the conical flask 1 through a grinding port; the center of the cock 3 has a round hole, and the airway 2 Put it into the round hole of the cock 3; there is a round hole in the center of the cock cover 4, which is placed on the cock 3 and coincides with the cock 3; The outer diameter is compatible; the top of the cock 3 is a circular plane.

[0054] A 100ml standard ground-mouth Erlenmeyer flask 1 can be taken, connected to the upper airway 2 (outer diameter 8.0mm, inner diameter 6.0mm, total length 180mm), which can also be connected with a ground-mouth adapter; the upper part of the plexiglass cock 3 is a round There is a circular hole in the center, the diameter of which is consistent with the inner diameter of the airway tube 2, a...

Embodiment 2

[0055] Embodiment 2 detection method of the present invention

[0056] Adopt the equipment described in embodiment 1, put a piece of lead acetate test paper on the top plane of cock 3, the test paper size is advisable to cover the aperture and not expose outside the plane, cover the cock cover 4, and tighten; take the Chinese medicinal material to be tested Or Chinese medicine decoction pieces are placed in the conical flask 1, after adding water, zinc particles, hydrochloric acid solution, immediately install the airway 2, the cock 3 with the lead acetate test paper, the cock cover 4, react for 40 minutes, take out the lead acetate test paper, and mix with Standard color comparison card is used to determine the limit of residual sulfur dioxide. The operation steps are as follows:

[0057] (1) Preparation of standard color chart

[0058] The pipetting concentration was 0.4mg·ml -1 , 0.3mg·ml -1 , 0.15mg·ml -1 、0mg·ml -1 Put 0.1ml of sulfur dioxide standard solution in the...

Embodiment 3

[0078] The condition investigation of embodiment 3 detection method of the present invention

[0079] 1. Instruments and materials

[0080] 1.1 Instrument

[0081] BP211D electronic balance (one hundred thousandth, German Sartorius company)

[0082] UPT-I-10T type Youpu UPT series ultrapure water device (Chengdu Ultrapure Technology Co., Ltd.)

[0083] DSY-1-2 hole constant temperature water bath (Beijing Guohua Medical Instrument Factory)

[0084] IXUS80 digital camera (Canon, 8 million pixels)

[0085] Rapid Determination Device for Residual Sulfur Dioxide (Patent No.: G01N21 / 78)

[0086] 1.2 Reagents and Reagents

[0087] Sodium bisulfite (Sinopharm Chemical Reagent Co., Ltd., content ≥99.8%);

[0088] Hydrochloric acid (AR, 36-38% HCL, Chengdu Kelong Chemical Reagent Factory);

[0089] Zinc particles (Sinopharm Chemical Reagent Co., Ltd., content ≥99.5%);

[0090] Lead acetate (Sinopharm Chemical Reagent Co., Ltd., content ≥99.8%);

[0091] Acetic acid (AR, Chengd...

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Abstract

The invention discloses a method for detecting sulfur dioxide residue limit of a traditional Chinese medicinal material or a traditional Chinese medicinal decoction tablet. Lead acetate test paper is adopted for detection in the method. When the sulfur dioxide residue limit in the traditional Chinese medicinal material or the traditional Chinese medicinal decoction tablet is detected by the method disclosed by the invention, only the traditional Chinese medicinal material or traditional Chinese medicinal decoction tablet to be detected and a reagent are added, and the test paper is installed; the steps such as titration and instrument judgment are not needed; the operation is simple; the reaction time is short; and the sulfur dioxide residue limit can be fast and accurately measured, and the obtained detection result coincides with that of an official method. Meanwhile, the device adopted by the method is cheap and available; the price is lower than that of the official method; the used reagent is less; the operation is simpler; the method is suitable for the measurement of the sulfur dioxide residue limit by various people, and the wide popularization of the technique is highly facilitated.

Description

technical field [0001] The invention relates to a method for detecting the residual amount of sulfur dioxide in Chinese medicinal materials or Chinese medicinal pieces. Background technique [0002] Sulfur dioxide is easily converted into sulfite ions, and sulfite ions have strong reducing properties. When oxidized, the coloring substances can be reduced and faded, which has the effect of bleaching medicinal materials. It can also inhibit the oxidase in medicinal materials and prevent Chinese medicinal materials from browning. Change, block the normal physiological oxidation process of microorganisms, inhibit the reproduction of microorganisms, and thus play an antiseptic effect. Therefore, sulfur fumigation is widely used in the processing of Chinese herbal medicines such as Ophiopogon japonicus. However, if the residual amount of sulfur dioxide is too large, it can cause strong irritation to the human stomach and intestines, and can combine with thiamine in the blood, caus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N31/22
Inventor 万丽吉琅廖晴曹纪亮胡一晨杨芳
Owner 广西众森中药制药有限公司