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Novel three-cavity transfusion bag for packaging long-chain fat emulsion injection, amino acid injection and glucose injection

A technology of glucose injection and infusion bag, which is applied in the field of medicine, can solve the problems of increasing the chance of infection of patients and the difficulty of better utilization of effective nutrients, and achieve the effect of reducing the risk of pollution

Inactive Publication Date: 2012-11-14
LIAONING HAISCO PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The infusion of multiple bottles in turn not only brought troubles for medical staff to repeatedly change bottles, constantly check, and adjust the drip rate, but more importantly, it also brought problems to patients such as increased chances of infection and difficulty in making better use of effective nutrients

Method used

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  • Novel three-cavity transfusion bag for packaging long-chain fat emulsion injection, amino acid injection and glucose injection
  • Novel three-cavity transfusion bag for packaging long-chain fat emulsion injection, amino acid injection and glucose injection
  • Novel three-cavity transfusion bag for packaging long-chain fat emulsion injection, amino acid injection and glucose injection

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0033] The preparation process of the three-chamber transfusion bag of the present invention

[0034]

[0035]

[0036]*: In the three-layer co-extrusion film for infusion, the outer film is composed of polypropylene, styrene-ethylene-butadiene block copolymer (7.5%); the middle film is composed of polypropylene / polyethylene, styrene-ethylene- Butadiene block copolymer composition (85%); the inner film is composed of polypropylene (7.5%).

[0037] **: The three-layer co-extrusion film for infusion comes from PolyCine GmbH, and the source of the outer film is code CFA100 (7.5%); the source of the middle film is code BFX101 (85%); the source of the inner film is code BFX284 (7.5%) ).

[0038] The percentages of the above-mentioned films are thickness parameters, that is, the proportions of the three layers of films in the total thickness.

experiment example 1

[0039] Experimental Example 1 - Appearance Inspection

[0040] Take 10 each of Examples 1-32 of the present invention, respectively, and visually observe them in a bright place with natural light, all of which are transparent, smooth, and free of foreign matter visible to the naked eye. There are no cracks, fissures, pores, colored inclusions and foreign matter deposits at the mouth tube interface.

experiment example 2

[0041] Experimental Example 2 - Identification

[0042] (1) Microscopic characteristics: 10 samples of each of Examples 1-32 of the present invention were taken, cut into appropriate thicknesses, and observed under a microscope. The cross-section showed clear three layers.

[0043] (2) Actual welding strength: Take the examples 1-32 of the present invention and measure them respectively according to the method of composite bag in the heat sealing strength measurement method (YBB00122003). The average value of each heat sealing part is not less than 25N / 15mm.

[0044] (3) Insufficient weld strength: Take Examples 1-32 of the present invention and measure them according to the composite bag method in the heat seal strength measurement method (YBB00122003), and the average value of each heat seal part is (5N-20N) / 15mm.

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a three-layer extrusion three-cavity transfusion bag. According to the three-cavity transfusion bag disclosed by the invention, intervals are formed at the connection positions of the cavities by insufficient solder through a hot-pressing method, and play the role of separating the liquid medicine in the three cavities when the liquid medicine is stored and conveyed, and when being used, the three-cavity transfusion bag can be opened conveniently by applying certain pressure, so that the three cavities are communicated, and further the liquid medicine in the three cavities can be mixed. Due to the implementation of the three-cavity transfusion bag disclosed by the invention, the mixed misoperation easily occurring when common transfusion solution is mixed can be avoided, the problems of the particles caused by puncturing, the cross contamination caused by mixing and the like can be reduced, the transfusion stability is improved, and the transfusion solution packaged by the three-cavity transfusion bag disclosed by the invention is very suitable for the clinical requirements on safety, rapidness, convenience in transfusion and treatment.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a three-layer co-extruded three-chamber infusion bag for packaging parenteral nutrition products. Background technique [0002] Parenteral nutrition is mainly suitable for patients with gastrointestinal dysfunction or failure. It supplies the nutritional elements needed by patients via intravenous route, mainly including caloric carbohydrates, fat emulsions, amino acids, vitamins, electrolytes and trace elements. From the perspective of body metabolism, the two basic elements for protein synthesis are energy and nitrogen sources, both of which are indispensable. The former (mainly glucose and fat) provide the driving force for synthesis, while the latter (essential amino acids) are the raw materials for protein synthesis. Only when caloric substances and nitrogenous substances are input at the same time, including electrolytes, vitamins, etc., can the anabolism be i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J1/10A61L2/04
Inventor 赵鑫源李国伟吴会斌
Owner LIAONING HAISCO PHARMACEUTICAL CO LTD
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