Unlock instant, AI-driven research and patent intelligence for your innovation.

Litchi seed dropping pill and preparation method thereof

A technology of lychee kernels and nuclear dripping pills, which can be applied in the fields of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of unreported patent medicines and achieve convenient clinical application, rapid drug effect, and bioavailability high effect

Inactive Publication Date: 2012-12-26
GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Lychee core is only used as a traditional Chinese medicine preparation for clinical application at present, and there are also reports of making tablets for experimental research, but there is no report as a patent medicine

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Litchi seed dropping pill and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Step 1: Prepare the extract of effective parts of litchi core:

[0021] Crush the lychee pits into a coarse powder. Take 100g of lychee seed powder, add 1000ml of 70v / v% ethanol for the first time, soak for 0.5 hours, then ultrasonically extract for 1 hour, pour the extract into the container for later use; hour, pour out the extract and combine it with the first extract; the extract is decompressed to recover ethanol until it has no alcohol smell, the extract is diluted with distilled water to 250ml, and left to stand overnight; The flow rate of the column bed volume is passed through the treated AB-8 macroporous resin column, and then eluted with 3 times the amount of pure water of the resin at a flow rate of 2 times the column bed volume per hour, discarding the water washing solution, and then 5 times the amount of pure water 75v / v% ethanol in the amount of medicinal materials elutes the effective substances on the resin at a flow rate of 2 times the column bed vol...

Embodiment 2

[0026] Step 1: Prepare the extract of effective parts of litchi core:

[0027] Crush the lychee pits into a coarse powder. Take 100g of lychee seed powder, add 800ml of 70v / v% ethanol for the first time, soak for 0.5 hours, then ultrasonically extract for 1 hour, pour the extract into the container for later use; hour, pour out the extract and combine it with the first extract; the extract is decompressed to recover ethanol until it has no alcohol smell, the extract is diluted with distilled water to 250ml, and left to stand overnight; The flow rate of the column bed volume is passed through the treated AB-8 macroporous resin column, and then eluted with 3 times the amount of pure water of the resin at a flow rate of 2 times the column bed volume per hour, discarding the water washing solution, and then 5 times the amount of pure water 75v / v% ethanol in the amount of medicinal materials elutes the effective substances on the resin at a flow rate of 2 times the column bed volu...

Embodiment 3

[0032] Step 1: Prepare the extract of effective parts of litchi core:

[0033] Crush the lychee pits into a coarse powder. Take 100g of lychee seed powder, add 900ml of 70v / v% ethanol for the first time, soak for 0.5 hours, then ultrasonically extract for 1 hour, pour the extract into the container for later use; hour, pour out the extract and combine it with the first extract; the extract is decompressed to recover ethanol until it has no alcohol smell, the extract is diluted with distilled water to 250ml, and left to stand overnight; The flow rate of the column bed volume is passed through the treated AB-8 macroporous resin column, and then eluted with 3 times the amount of pure water of the resin at a flow rate of 2 times the column bed volume per hour, discarding the water washing solution, and then 5 times the amount of pure water 75v / v% ethanol in the amount of medicinal materials elutes the effective substances on the resin at a flow rate of 2 times the column bed volu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a litchi seed dropping pill. The dropping pill comprises 1 part of litchi seed extracts and 3-5 parts of matrix by weight, wherein the matrix is the mixture of polyethylene glycol 4000 and polyethylene glycol 6000 in a weight ratio of (1:1) to (1:2); the litchi seed extracts are obtained by carrying out ultrasonic extraction on litchi seed drugs twice with 70v / v% of ethanol and vacuum-drying the extracts at room temperature after purifying the extracts with AB-8 macroporous resins and contain litchi seed total flavonoids, total saponins and tannins; and the total content of the litchi seed total flavonoids, total saponins and tannins is above 70%. The invention also provides a method for preparing the litchi seed dropping pill. Compared with the prior art, the litchi seed dropping pill has the advantages of stable physicochemical property, suitability for long-time storage, high bioavailability, quality controllability, simplicity of process and convenience for clinical application.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine extraction, and in particular relates to a litchi seed dropping pill and a method for preparing the litchi seed dropping pill. Background technique [0002] Lychee Seed, Litchi Seed, is the dry mature seed of Sapindaceae plant Litchi (Litchi Chinensis). Warm, sweet in taste, slightly bitter, has the effects of promoting qi and dispelling stagnation, dispelling cold and relieving pain. "Compendium of Materia Medica" records that lychee cores "quench thirst, benefit people's color, and eat them to relieve polydipsia" (polydipsia, modern medicine is called diabetes). Studies have shown that lychee core has the functions of lowering blood sugar, regulating blood lipids, improving anti-oxidation, and inhibiting the surface antigen of hepatitis B virus. The ingredients contained in lychee kernels have been well studied. The main ingredients are saponins, flavonoids and anthocyanins, phytost...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/77A61K47/34A61K9/20A61P3/10A61P29/00A61P3/06A61P39/06A61P31/20A61P3/00A61K131/00
Inventor 郭洁文钟世顺叶碧波
Owner GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE