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Medicinal food formula and medicinal edible preparation for preventing and treating hyperuricemia and gout

A technology for hyperuricemia and dual use of medicine and food, which is applied to a dual-use medicine and food formulation for preventing and treating hyperuricemia and gout, a preparation method and the field of dual use of medicine and food in the prevention and treatment of hyperuricemia and gout , which can solve problems such as damage, many adverse reactions, and the existence of adverse reactions

Inactive Publication Date: 2013-01-30
张清仲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs have many adverse reactions, and benzbromarone can cause severe liver damage and adverse reactions to the nervous system
([5] Zhang Kaida. One case of serious adverse reaction of the nervous system caused by gout and Lixian. Chinese Journal of Hospital Pharmacy, 2000; 20: 639.) Allopurinol is the only xanthine oxidase inhibitor used clinically, which can inhibit Xanthine oxidase inhibits the production of uric acid, but its existence can cause skin allergies, liver damage, life-threatening hypersensitivity allergic syndrome and other toxic side effects
Uric acid-lowering western medicine, due to the single variety and adverse reactions, limits the clinical application

Method used

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  • Medicinal food formula and medicinal edible preparation for preventing and treating hyperuricemia and gout
  • Medicinal food formula and medicinal edible preparation for preventing and treating hyperuricemia and gout
  • Medicinal food formula and medicinal edible preparation for preventing and treating hyperuricemia and gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Embodiment 1: formula of the present invention makes capsule dosage form

[0053] 1) Weigh 60g of plantain seed and 60g of dodder seed

[0054] 2) Add 10 times the amount of 60% ethanol to the raw material and reflux extract twice, each time for 1.5 hours, recover the ethanol solution under reduced pressure, and centrifuge the concentrated solution at high speed to obtain filtrate 1. Add 10 times the amount of purified water to the residue, decoct twice, 2 hours each time, concentrate the decoction to the amount of medicinal materials, and centrifuge at high speed to obtain filtrate 2, combine filtrates 1 and 2, concentrate in vacuum, vacuum dry or spray dry to obtain fine powder, Granulated and packed in capsules.

Embodiment 2

[0055] Embodiment 2: the formula of the present invention makes tablet dosage form

[0056] 1) Weigh 30g of psyllium and 20g of dodder

[0057] 2) Add 10 times the amount of 60% ethanol to the raw material and reflux extract twice, each time for 1.5 hours, recover the ethanol solution under reduced pressure, and centrifuge the concentrated solution at high speed to obtain filtrate 1. Add 10 times the amount of purified water to the residue, decoct twice, 2 hours each time, concentrate the decoction to the amount of medicinal materials, and centrifuge at high speed to obtain filtrate 2, combine filtrates 1 and 2, concentrate in vacuum, vacuum dry or spray dry to obtain fine powder, Add 100 ml of 15% PVP (polyvidone) ethanol solution, granulate, dry, and compress into tablets.

Embodiment 3

[0058] Embodiment 3: the formula of the present invention makes oral liquid dosage form

[0059] 1) Weigh 50g of psyllium and 100g of dodder

[0060] 2) Add 10 times the amount of 60% ethanol to the raw material and reflux extract twice, each time for 1.5 hours, recover the ethanol solution under reduced pressure, and centrifuge the concentrated solution at high speed to obtain filtrate 1. Add 10 times the amount of purified water to the residue, decoct twice for 2 hours each time, concentrate the decoction to the amount of medicinal materials, centrifuge at high speed to obtain filtrate 2, and combine filtrates 1 and 2. Dilute the extract to a relative density of 1.2, and bottle it to make oral liquid.

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Abstract

The invention belongs to the field of traditional Chinese medicines, relates to traditional Chinese medicines and health care preparations, and especially relates to a medicinal food formula and a medicinal edible preparation for preventing and treating hyperuricemia and gout. The medicinal edible preparation comprises traditional Chinese medicines or active ingredients of 10 to 80 parts of plantain seed and 10 to 80 parts of semen cuscutae. The medicinal edible preparation is prepared from extract of plantain seed and semen cuscutae, and auxiliary materials, and can be processed into tablets, pills, electuary, an oral liquid, a tea bag and a health-care food additive. An animal acute toxicity test and a sub-chronic toxicity test prove that the medicinal edible preparation is safe and has no toxic or side effect. A pharmacodynamic animal test proves that the medicinal edible preparation can obviously reduce blood uric acid and improve kidney uric acid crystallization and injuries. The medicinal edible preparation as a treatment drug or a health-care product can be used for patients suffering from hyperuricemia and gout, can obviously reduce a blood uric acid level and relieve gouty arthritis symptoms, and has good safety.

Description

technical field [0001] The invention relates to the fields of health food and traditional Chinese medicine. In particular, it is a medicine and food dual-purpose formula preparation for preventing and treating hyperuricemia and gout. Specifically, the Chinese patent medicine or health food is prepared by using the dual-purpose traditional Chinese medicine as a raw material. The invention also relates to a preparation method of the formula and its dual use of medicine and food in preventing and treating hyperuricemia and gout. Background technique [0002] After the 1980s, with the improvement of economic living standards, dietary structure and living habits have changed, making the incidence of hyperuricemia and gout increase year by year. Scholars at home and abroad have conducted a lot of research on it. In terms of epidemiology, the incidence of hyperuricemia varies with race and region, and reports from various countries are inconsistent. The incidence of gout in my cou...

Claims

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Application Information

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IPC IPC(8): A61K36/68A61P19/06A23F3/14
Inventor 全金花张清仲
Owner 张清仲
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