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Natural oregano oil emulsion and preparation process thereof

An oil emulsion and emulsifier technology, applied in the field of natural oregano oil emulsion and its preparation technology, can solve the problems of inconvenient application, high irritation, volatile and unstable oregano oil, etc., and achieve small emulsion droplets and thermal stability. Good performance and uniform dispersion

Inactive Publication Date: 2013-02-13
QINGDAO VLAND BIOTECH INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The main purpose of the present invention is to solve the shortcomings of oregano oil that is volatile, unstable, highly irritating, and inconvenient to use, and provide the market with a stable, high-quality, green, safe, five-drug resistance, no residue, and easy to use New drug preparations for animals

Method used

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  • Natural oregano oil emulsion and preparation process thereof
  • Natural oregano oil emulsion and preparation process thereof
  • Natural oregano oil emulsion and preparation process thereof

Examples

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Effect test

Embodiment 1

[0044] oregano oil

[0045] Preparation method and steps: Dissolve benzyl alcohol in purified water, add Span 80, Tween 80 and propylene glycol, stir and dissolve to form solution A, add solution A to the colloid mill, adjust the speed to 2000 rpm, stir and mix for 5 minutes ; Dissolve oil-soluble antioxidants BHA and BHT in ethanol, add to oregano oil to become solution B, slowly add liquid B to liquid A in the colloid mill, emulsify for 30 minutes; then filter and pack to obtain 2% Oregano Oil Emulsion.

Embodiment 2

[0047] oregano oil

[0048]Preparation method and steps: dissolve benzyl alcohol in purified water, add Span 80, Tween 80 and glycerol, stir and dissolve to form solution A, add solution A to the colloid mill, adjust the speed to 4000 rpm; Soluble antioxidants BHA and BHT are dissolved in ethanol and added to oregano oil to form solution B. Slowly add liquid B to liquid A in the colloid mill and emulsify for 40 minutes; then filter and pack to obtain 5% oregano oil emulsion.

Embodiment 3

[0050] oregano oil

[0051] Preparation method and steps: Dissolve oil-soluble antioxidants BHA and BHT in ethanol, add to oregano oil, then add Span 80, Tween 80 and glycerin, stir and mix evenly to form solution C, add solution C to Colloid mill, adjust the speed to 5000 rpm, stir and mix for 5-10 minutes; dissolve phenol in purified water to become solution D, add solution D to solution C in the colloid mill, and emulsify for 60 minutes; then filter and pack , That is, 8% oregano oil emulsion.

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Abstract

The invention discloses a composition of a natural oregano oil emulsion and a preparation process thereof. The emulsion is a medicine for animals, oregano oil extracted from natural oregano is used as a raw material, a nonionic surface active agent is used as an emulsifying agent, low-carbon fatty alcohol is used as an auxiliary emulsifying agent, purified water is used as an aqueous phase, appropriate quantities of antiseptic agents and antioxidant agents are added, and by means of the emulsifying process of a colloid mill, the oregano oil emulsion is prepared. The natural oregano oil emulsion and the preparation process thereof have the advantages that the process is simple, the product is stable, the natural oregano oil emulsion is nonirritating during clinical usage, the mass production is facilitated, and excellent popularization and application values are achieved.

Description

technical field [0001] The invention relates to an animal medicine oregano oil emulsion for antibacterial, antidiarrheal and growth promoting for livestock and poultry and its preparation process. Background technique [0002] Oregano oil, the extract of natural plant oregano, is a natural antibiotic. Oil of oregano is not pure, but rather a mixture of compounds that contribute to the aroma. The chemical constituents of oregano oil are mainly thymol, carvacrol, γ-terpinene and ρ-cymene. Its thymol and carvacrol have the greatest antibacterial activity, and are the precursors of biosynthesis of thymol and carvacrol, both of which have antimicrobial activity. [0003] Oregano oil has antibacterial and bactericidal functions, and its antibacterial activity is mainly realized through the denaturation and coagulation of bacterial cell wall structural proteins. Dispersion leads to blockage of key intracellular processes, resulting in leakage of cellular components, loss of wate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61K9/107A61P1/12A61P31/04
Inventor 郝智慧栾明娜贾德强刘元元冯培生张瑞丽沈巍
Owner QINGDAO VLAND BIOTECH INC
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