A kind of bee venom composition with sunscreen effect

A composition and bee venom technology, applied in the directions of drug combinations, preparations for skin care, cosmetics, etc., can solve the problems of skin irritation and phototoxicity, skin dependence, easy to block pores, etc., and achieve good spreadability and reduce skin irritation. Damage, no skin irritation effect

Active Publication Date: 2014-10-29
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a safer and more efficient sunscreen cosmetics for the problems that the existing sunscreen cosmetics have strong irritation and phototoxicity to the skin, a large amount of use will cause the skin to become dependent, the skin feels greasy, has poor air permeability, and is easy to clog pores. Bee venom composition with sun protection effect

Method used

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  • A kind of bee venom composition with sunscreen effect
  • A kind of bee venom composition with sunscreen effect

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Experimental program
Comparison scheme
Effect test

Embodiment 2

[0037] The crude bee venom was collected by a bee venom collector, fully dissolved by adding 10 times the volume of water, centrifuged at 5000g for 30min, the supernatant was ultrafiltered through an ultrafiltration membrane with a molecular weight cut-off of 10000Da, and the filtrate was freeze-dried to obtain bee venom.

[0038] The bee venom composition with sunscreen effect of the present embodiment is composed of the following components according to the total mass percentage of 100%:

[0039] Phase A: 1.5% disodium salt of 2,2′-bis-(1,4-phenylene) 1H-benzimidazole-4,6-disulfonic acid, methylene bis-benzotriazolyl tetra 1% of methyl butylphenol, 0.2% of carbomer, 4% of glycerin, 3% of propylene glycol, and the balance of deionized water.

[0040] Phase B: bis-ethylhexyloxyphenol methoxyphenyl triazine 0.2%, ethylhexyl methoxycinnamate 8%, TiO 2 / Hydrated Silica / Aluminum Hydroxide / Dimethicone / Methylsiloxane Copolymer 0.5%, Ceteareth-21.5%, Cetearyl Ether-212%, Jojo...

Embodiment 3

[0046] Purchase wasp crude bee venom from Wuhan Yimin Bee Products Co., Ltd., add 30 times the volume of water to fully dissolve, centrifuge at 10,000 g for 10 minutes, and ultrafilter the supernatant through an ultrafiltration membrane with a molecular weight cut-off of 10,000 Da, then freeze-dry the filtrate to obtain bee venom .

[0047] Use a bee venom collector to collect crude bee venom, add 30 times the volume of water to fully dissolve, centrifuge at 10,000 g for 10 min, and ultrafilter the supernatant through an ultrafiltration membrane with a molecular weight cut-off of 10,000 Da, then freeze-dry the filtrate to obtain bee venom.

[0048] The bee venom composition with sunscreen effect of the present embodiment is composed of the following components according to the total mass percentage of 100%:

[0049] Phase A: methylenebis-benzotriazolyltetramethylbutylphenol 0.1%, terexylylenebiscamphorsulfonic acid 4.5%, phenylbenzimidazolesulfonic acid and its potassium, sodi...

Embodiment 4

[0055] Purchase honeybee crude bee venom from Fujian Shenfeng Technology Development Co., Ltd., add 15 times the volume of water to fully dissolve, centrifuge at 6000g for 20min, and ultrafilter the supernatant through an ultrafiltration membrane with a molecular weight cut-off of 10000Da, then freeze-dry the filtrate to obtain bee venom .

[0056] The bee venom composition with sunscreen effect of the present embodiment is composed of the following components according to the total mass percentage of 100%:

[0057] Phase A: 4.5% disodium salt of 2,2′-bis-(1,4-phenylene) 1H-benzimidazole-4,6-disulfonic acid, phenylbenzimidazole sulfonic acid and its potassium, Sodium and Triethanolamine Salt 3%, Xanthan Gum 0.4%, Acrylate / C 10-30 0.6% of alkyl acrylate crosslinked polymer, 0.1% of EDTA-2Na, 5% of glycerin, 5% of propylene glycol, 5% of butanediol, and the balance of deionized water.

[0058] Phase B: 0.5% bee venom (added in the form of a 10% bee venom solution prepared in a...

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Abstract

Disclosed is a bee venom composition with a sun-proof effect. The bee venom composition comprises a sun-proof cosmetic substrate component, and further comprises bee venom. According to the present invention, the bee venom is applied in sun-proof cosmetics for a first time, can effectively prevent ultraviolet ray from hurting skin, relieve skin inflammation caused by sunburn, and enable the skin to keep humidification, provide nutrient for the skin, prompt the rehabilitation of hurt skin, and improve the self-protecting capability of the skin. In addition, according to the invention, the bee venom, algal polysaccharides and Vc phosphate magnesium are compounded, thereby remarkably improving effects of the bee venom compound such as sun resistance, inflammation diminishment and repair after being exposed to the sun. The bee venom composition with the sun-proof effect comprises cream, emulsion, water aqua, gelatum, and gel, and is suitable for user groups with various types of skin.

Description

Technical field: [0001] The invention belongs to the field of cosmetics, in particular to a bee venom composition with sunscreen effect. Background technique: [0002] With the aggravation of environmental pollution and the degree of destruction of the atmosphere, the ultraviolet rays irradiated on the ground are also becoming more and more intense. Among them, UVB (ie UVB) has the strongest ability to act on the skin, reaching the surface of the dermis, making the blood vessels of the dermis dilate and appear red and swollen, and the nucleic acid or protein in the epidermal cells denatured. After long-term exposure, the skin will appear edema, blisters, erythema, peeling, aging, and even cause skin cancer. And UVA (that is, long-wave ultraviolet rays) has stronger penetrating power, can reach deep in the dermis, and has a cumulative effect on the skin. After long-term exposure, the skin will brown, collagen fibers will break, elasticity will decrease, and wrinkles will fo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/98A61K8/73A61P17/04A61Q19/00
CPCA61K8/987A61Q17/04A61P17/04
Inventor 陈华孙恢礼潘剑宇蔡冰娜孙小钰
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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