Cosmetic compositions comprising ficus serum fraction and methods to reduce the appearance of skin hyperpigmentation

A cosmetic composition, fig technology, applied in the field of reducing the appearance of skin hyperpigmentation, topical skin lightening composition, can solve the problems of environmental hazards, inability to present the full picture of active substances, toxic chemical waste, etc.

Active Publication Date: 2013-05-08
PROCTER & GAMBLE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, traditional extraction methods often fail to present a complete picture of active substances present in plant cells and thus fail to realize the full potential of plant-based cosmetic formulations
Additionally, many traditional extraction methods use strong chemical solvents, which are not 'natural' and are therefore substances that consumers wish to avoid applying to their skin
Additionally, these solvent-based processes generate toxic chemical waste that can harm the environment if not properly treated and destroyed as hazardous waste

Method used

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  • Cosmetic compositions comprising ficus serum fraction and methods to reduce the appearance of skin hyperpigmentation
  • Cosmetic compositions comprising ficus serum fraction and methods to reduce the appearance of skin hyperpigmentation
  • Cosmetic compositions comprising ficus serum fraction and methods to reduce the appearance of skin hyperpigmentation

Examples

Experimental program
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Effect test

preparation example Construction

[0048] Preparation of Fig Serum Fraction

[0049] The method used to isolate compounds from plant material, eg, by extraction with a solvent, determines which compounds are isolated. Consistent with the general principle of "like dissolves like", the choice of extraction solvent essentially determines the type and amount of compounds obtained by any particular extraction technique. For example, polar compounds are extracted by using polar solvents, and non-polar compounds are extracted by using non-polar solvents. This allows for the isolation of only a small range of compounds that may be present. The correlation between solvent polarity and the type of species isolated using conventional solvent extraction is depicted in the diagram below (Houghton & Raman, Laboratory Handbook for the Fractionation of Natural Extracts (1998)).

[0050]

[0051] The fig serum fraction of the present invention is not prepared by solvent extraction, but by separating the fresh cell juice...

example 5

[0091] Proteins, including those in plants such as figs, can cause contact dermatitis in allergic individuals. Shortly after exposure to the pathogenic proteinaceous material, such individuals may experience symptoms such as acute urticaria or a vesicular eruption of the skin, often with itching, burning, and / or stinging. (V. Janssens et al., "Protein contact dermatitis: myth or reality?", British Journal of Dermatology, 1995; 132:1-6) It is therefore highly desirable that skin care substances contain as little protein as possible.

[0092] The total protein content of FSF was determined by the Kjeldahl method (Example 1, Table 3). No protein was detected in FSF. As used herein, "essentially protein-free" means less than 1% (0% to 1%) total protein as determined by the Kjeldahl method. In some embodiments, the protein content of FSF is 0% to 1%, in other embodiments 0% to 0.5%, and in other embodiments 0% to 0.25%.

[0093] Chromaticity / Chromaticity Stability

[0094] ...

example 1

[0181] Preparation of Bioactive Serum Fractions Derived from Fresh Ficus Bengal Leaves .

[0182] figure 1 As a schematic, one example of a method of preparing a bioactive serum fraction from fresh fig leaves is shown.

[0183] Collect enough fresh Ficus bengal leaves to obtain about 100 kg dry matter. The dry matter content in the fresh leaves was measured to be 32.01%, and about 312.4 kg of fresh plant leaves need to be harvested to obtain 100 kg of dry matter. Care is taken to maintain the inherent moisture content in fresh leaves and to avoid wilting due to moisture loss. Collection is carried out in such a way as to avoid or minimize any damage to the collected fresh leaves. All steps are performed in the shortest possible period of time to minimize exposure of the fresh leaves to sunlight, heat, and other adverse environmental factors.

[0184] Then within ≤5 minutes and ≤1kg / cm 2The collected leaves are washed under water pressure to remove dirt particles and ot...

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Abstract

The present invention provides cosmetic compositions comprising Ficus serum fraction derived from fresh Ficus cell juice of fresh Ficus leaves. The cosmetic composition also comprises a cosmetically acceptable carrier. The Ficus serum fraction is present in the composition at a cosmetically effective amount for achieving the desired skin lightening result.

Description

technical field [0001] The present invention relates to the field of skin lightening by topical application of cosmetic compositions to the skin. The present invention also relates to topical skin lightening compositions comprising a fig serum component. The present invention also relates to a method of reducing the appearance of hyperpigmented skin by topically applying said cosmetic composition to a hyperpigmented area to disrupt one or more steps of melanin synthesis. Background technique [0002] Human skin consists of three main layers: the epidermis, dermis, and subcutaneous fat layer. The epidermis consists of four layers (from top to bottom): stratum corneum, stratum granulosa, stratum spinosum, and stratum basal. A separate fifth transparent layer may exist between the stratum corneum and the granular layer. The basal layer produces cells that gradually migrate upward to form the other epidermal layers. As these cells migrate upward, they lose their central nucl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02
CPCA61K2236/31A61K8/97A61K36/60A61Q19/02A61K8/9789
Inventor C·L·斯旺森M·科加诺夫S·惠特克L·T·劳林二世箱崎智洋L·R·罗宾森J·C·柏曼J·M·普莱斯K·G·克隆霍姆
Owner PROCTER & GAMBLE CO
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