85 results about "Solvent polarity" patented technology

The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

A method of manufacturing a chemical-mechanical polishing (CMP) pad comprises the steps of (a) forming a layer of a polymer resin liquid solution (i.e., a polymer resin dissolved in a solvent); (b) inducing a phase separation in the layer of polymer solution to produce an interpenetrating polymeric network comprising a continuous polymer-rich phase interspersed with a continuous polymer-depleted phase in which the polymer-depleted phase constitutes about 20 to about 90 percent of the combined volume of the phases; (c) solidifying the continuous polymer-rich phase to form a porous polymer sheet; (d) removing at least a portion of the polymer-depleted phase from the porous polymer sheet; and (e) forming a CMP pad therefrom. The method provides for microporous CMP pads having a porosity and pore size that can be readily controlled by selecting the concentration polymer resin in the polymer solution, selecting the solvent based on the solubility parameters of the polymer in the solvent polarity of solvent, selecting the conditions for phase separation, and the like.

The invention relates to a copper ion/mercury ion fluorescence molecular probe, and a preparation method and application thereof. The invention mainly aims to solve the problem of single detection ion in the fluorescence molecular probe for detecting copper ions or mercury ions in the prior art, and the problems of low sensitivity, poor selectivity, high sensitivity to pH value, and the like in most fluorescence molecular probes. The preparation method of the fluorescence molecular probe comprises the following steps: (1) dissolving 1 part of rhodamine B in ethanol, adding 2-5 parts of hydrazine hydrate at room temperature, stirring under reflux for 1-2 hours, cooling, and filtering to obtain a precipitate; and (2) adding 1 part of precipitate into 50-500 parts of mixed solvent composed of methanol and dichloromethane in a volume ratio of 3:1, adding 2-6 parts of 40-60wt% formalin, stirring at room temperature in a nitrogen atmosphere for 6-8 hours, evaporating under reduced pressure to remove the solvent, and carrying out silica gel chromatographic separation to obtain the fluorescence molecular probe. The invention has the advantages of high fluorescence quantum yield, low sensitivity to solvent polarity, high chemical/light stability and the like.

The invention provides a purification method of lithium bis(fluorosulfonyl)imide. The method comprises the following steps of (1) dissolving a lithium bis(fluorosulfonyl)imide crude product in an organic solvent; filtering to remove insoluble substances and obtain filter liquid; (2) mixing the filter liquid and organic acid anhydride and then heating to obtain mixed liquid, wherein the organic acid anhydride has a structure shown as a formula I, and in the formula I, R1 and R2 are independently selected from C1-C5 alkyls or C1-C5 halogen alkyls; (3) performing evaporation treatment on the mixed liquid to remove the organic solvent and obtain an intermediate product; (4) crystallizing the intermediate product in a low-polarity organic solvent to obtain a lithium bis(fluorosulfonyl)imide pure product, wherein the polarity of the low-polarity organic solvent is lower than 4. The purification method provided by the invention has the advantages that the organic acid anhydride is used for removing moisture in the lithium bis(fluorosulfonyl)imide crude product; other impurities are not introduced; the recrystallization is performed through solvent polarity regulation. The purification method provided by the invention has the advantages that the process is simple; the obtained lithium bis(fluorosulfonyl)imide has high purity.

The invention discloses monodisperse superparamagnetic nano crystal colloidal core-shell composite particles, which are monodisperse superparamagnetic nano cluster particles which are gathered by ferroferric oxide nanocrystalline. The surfaces of the particles are coated by polyvinylpyrrolidone. The preparation method of the composite particles comprises the following steps: adding trivalent iron salt to polyol mixture solution of polyvinylpyrrolidone and polyhydroxy compounds; agitating until the trivalent iron salt is completely dissolved; adjusting the pH value to 8.0-10.0, then carrying out enclosed heating to 180-240 DEG C, and carrying out heat preservation for 6-48 hours. The monodisperse superparamagnetic nano crystal colloidal core-shell composite particles disclosed by the invention can be assembled into different colors of photonic crystal in a magnetic control manner; the dependency level of the magnetic photonic crystal on the solvent polarity, the ion strength and the pH value can be reduced.

The invention discloses a method for extracting sialic acid from bird nests by means of crystallization. The method comprises the steps of soaking the bird nests with deionized water and removing impurities; then pulping and crushing, heating under a high pressure, centrifuging, drying, dissolving and crystallizing to obtain the sialic acid. According to the method disclosed by the invention, hydrolysis of the glycoproteins of the bird nests is accelerated through serious heating by means of high-pressure heating, and the combined-state sialic acid is converted to a free-state sialic acid; the high-pressure heating avoids the introduction of other ingredients, thereby simplifying the subsequent separation and purification steps; the sialic acid crude product obtained by freeze-drying is prepared into alcohol-saturated solution by virtue of the property that the sialic acid is slightly dissolved in alcohol but proteins and polysaccharides are insoluble in alcohol, and therefore on one hand, the impurities such as alcohol-insoluble proteins and polysaccharides are removed, on the other hand, the solvent polarity is changed by adding a non-polar solvent, and sialic acid crystals are obtained according to the different seperation sequences of the sialic acid and the impurities. According to the method disclosed by the invention, sialic acid extraction steps are simplified, and industrial pollution is reduced.

The invention provides a molecular blot absorbent of a SiO2 particle surface in a water phase system and a preparation method thereof, which overcomes the defects of low identification ability and low service life caused by mismatched solvent polarity or by using toxic organic solvent in synthesis in the prior art. The preparation method is provided with the following steps: firstly, activating treatment is adopted to SiO2 particles, and the particles react with a functional monomer and target phenolic pollutants such as one of chlorophenols or nitrophenol to form a complex type precursor body; the molecular blot absorbent of the SiO2 particle surface is obtained through polymerization and post treatment after the re-oxidation. The molecular blot absorbent of the invention is simple in preparation technique and low in cost; the absorbent has high selectivity in target molecules, a fast balancing speed in absorption and de-sorption and can be repeatedly used.

The invention provides a fluorescent probe for detecting the polarity of a lipid droplet. The chemical name is 3-(4-(2,2-dicyanylvinyl)phenyl)-9-ethylcarbazole, and the structural formula is as shownin the specification. Due to the intramolecular distorted electron transfer effect (TICT) of the probe, a good response to solvent polarity is achieved. The fluorescent probe of the invention is electrically neutral, and can be well positioned in lipid droplets in cells. The probe can be accurately located in lipid droplets, has high sensitivity, good optical stability and specific response to polarity, and achieves detection of polarity of lipid droplets in cells. A method for synthesizing the probe has the advantages of simple steps, convenient purification and high yield.

A process for preparing the refined palmatine from general fibraurea alkaloid faetures that the principle that different kinds of alkaloid have the difference in pH value and solvent polarity is used for separation or the column photography is used for separation, and the relative refining technique is also used to make its purity be 99.0% or more.

The invention discloses application of a sulfydryl silver cluster coordination polymer in organic solvent detection, and belongs to the cross field of nanometer materials and coordination chemistry. The polymer is a silver/sulfur cluster-based porous coordination polymer with the 12-core silver/sulfur cluster as the node and bridged with a bi-toothed organic ligand. The chemical formula of the compound is [(Ag12(SBu(i)t(/i))8(CF3COO)4(bpy)4)](i)n(/i). The material has amphiphilic ducts and has high capacity for adsorbing small solvent molecules. The solvent molecules in the ducts interact with the ligand to affect the excited state energy level of the material, so that the fluorescent performance of the material changes in different polar solvents. Excellent linear relation exists between the solvent polarity and the fluorescence maximum emission peak wavelength of the material. Therefore, organic solvents can be recognized and detected according to fluorescence spectra. The silver/sulfur cluster-based porous coordination polymer has the advantages of being free of invasion and high in sensitivity and safety and has good application prospects in organic solvent recognition and detection.

Apparatus and process for removing and/or converting contaminants in water-miscible organic solvent mixtures by surface interaction effects to forms less objectionable with lesser metabolic impacts for humans. The process both changes distillation entrapped contaminant compounds in-situ and effects removal of the compounds and their reaction products. In what follows, water-miscible-organic-solvent and water mixtures can be substituted for alcohols. The alcohol to be treated is placed in a ventilated vessel leaving room for head space. Contaminant free air or a specific organic-contaminant-free gas is injected into or otherwise placed in contact with the alcohol. A vacuum is pulled within the vessel, which draws the gas through the alcohol into the head space creating gas bubbles. Energy within a specified range of frequencies is imparted to the fluid causing cavitation and reaction. Wetting, solvent polarity characteristics and pressure are fixed or varied dynamically during processing, and inert or reactive gases are added. Reacted and unreacted contaminants enter the bubble cavities and are swept from solution.

The invention discloses an extraction purification process of teasel root saponin. The technical scheme includes that: teasel medicinal material coarse powder is subject to rough extraction process toobtain teasel saponins; the teasel saponins is added with water to be dissolved, temperature or solvent polarity is reduced until the teasel saponin VI is fully sedimented, the sediment is obtained by filtering or centrifugation, and the operations are repeated for 1-3 times to obtain teasel saponin VI monomer. The invention has the beneficial effects that: the process is lower in cost compared with that macroporous resin is adopted, thus environmental pollution is avoided; water is taken as mother solution for precipitation purification, thus the influence of other glycosides in the saponinson the purity of teasel saponin VI is effectively eliminated; and an amount of organic solvent is added into precipitation mother solution, thus educt quantity can be increased while hydrolysis of saponin is avoided.

The invention discloses a synthesis method and size selective catalytic application of a hollow porous polymer nanosphere composite material encapsulated by noble metal nanoparticles. Firstly, a porous polymer nanosphere network material with a hollow structure is synthesized by a reversible addition-fracture chain transfer polymerization and friedel-crafts overcrosslinking one-pot reaction. Then,the material is used as a main carrier, various guest noble metal nanoparticles are encapsulated respectively into hollow cavities through an impregnation-reduction method, and the final hollow porous polymer nanosphere composite material encapsulated by the noble metal nanoparticles is formed. The synthesis method and size selective catalytic application of the hollow porous polymer nanosphere composite material encapsulated by the noble metal nanoparticles further focus on taking the hollow porous polymer nanosphere composite material encapsulated by palladium metal nanoparticles as a heterogeneous catalyst, and solvent polarity-induced catalytic hydrogenation application with adjustable size selectivity is provided.

The invention provides a method of measuring residual liquid hydrocarbon content in shale via low-field nuclear magnetic resonance. A shale sample of any shape is used to saturate manganese chloride solution of sufficient concentration; low-field nuclear magnetic resonance is then performed to obtain a nuclear magnetic T2 spectrum in the shale sample; the shale sample is subjected to dewatering prior to dealkylation; a T2 spectrum signal is measured again; amplitude integral difference delta S of the T2 spectral signal is introduced into a calibration relationship (namely, a marking equation)of hydrocarbon content and the signal, built in the method, so as to calculate hydrocarbon volume in shale of unit volume; the result is that the hydrocarbon volume in shale of unit volume is presented by percentage, which is considered as residual liquid hydrocarbon content in shale. The problems are effectively avoided that samples experience light hydrocarbon loss due to crushing pretreatment and that insufficiency of solvent polarity leads to incomplete extraction of heavy hydrocarbons; the method is suitable for precisely measuring residual hydrocarbon content in shale and is an effectiveand quick measuring method.

A preparation method of wet-white leather comprises the following steps: regulating pH of naked leather to a value which is close to an isoelectric point of the leather, and then squeezing water; adding the leather after water is squeezed in a sealing device, adding anhydrous ethanol of which the weight is 2-4 times that of the leather and dehydrating, rotating for 5-240 min and then recycling bath lotion; repeating dehydrating operation for 2-4 times; then preparing a mixed solution of which the polarity is higher than ethanol, dehydrating for 1-3 times, rotating for 30-600 min and then recycling the bath lotion, wherein the use amount of the mixed solution every time is 100-400% of the weight of the leather; and finally, adding an acetone solution of which the weight is 100-400% of the weight of the leather, rotating for 5-240 min and then taking out the leather so as to obtain the wet-white leather, wherein the water content of the leather is lower than 10%. A solvent polarity increasing step-by-step dehydrating mode is adopted, the preparation method is not affected by the original state or thickness of the naked leather, water on the surface of the naked leather and water in the naked leather can be slowly and uniformly replaced out, and therefore, the wet-white leather which has a porous fiber structure and is good in physical and mechanical properties is obtained.

The invention discloses a polarity-sensitive fluorescence probe and a preparation method and application thereof. A structural formula of the probe is as shown in the specification, wherein R1 is H, CH3, CH3CH2 or COOH; and R2 is CH3, CH3CH2 or CH3CH2CH2. The preparation method comprises the following steps: reacting a reactant 1 and a reactant 2 at a low temperature in an anhydrous anoxic reactor; and adding a reactant 3, reacting at a room temperature, and carrying out treatment such as skimming and purification, so as to obtain the probe. The probe has the specific fluorescence response on the solvent polarity, and is fast in response; the fluorescence wavelength is relatively large during response; the preparation method is simple; and the response detection on the solvent polarity is convenient.

The invention discloses a 9,10-diphenyl anthracene derivative as reactive luminescent agent, a preparation method thereof and a high-efficiency weak light upconversion system prepared from the reactive luminescent agent 9,10-diphenyl anthracene derivative. Reactive upconversion luminescent agents are obtained by introducing reactive groups (such as benzaldehyde and decyl alcohol) into the 9,10-position of the anthracene ring; meanwhile, by introducing an aldehyde group and hydroxyl formaldehyde into different positions (such as ortho-, meta-, and para-), energy level difference (DEST) of singlet state (ES) and triplet state (ET) of the reactive luminescent agent is changed, and a plurality of novel luminescent agents with higher upconversion efficiency than that of a current star luminescent agent DPA are obtained. The luminescent agent has selective upconversion response characteristic to solvent polarity, and the upconversion efficiency obtained by a binary system prepared from the luminescent agent and a photosensitizer exceeds the highest value reported in the prior art.

The invention belongs to the field of organic light-emitting materials, and particularly relates to a di(4-benzoindole)sulfone derivative and a preparation method and application thereof. The di(4-benzoindole)sulfone derivative refers to an intramolecular charge transfer compound formed by using an indole derivative as the electron donor and diphenyl sulfone as the electron acceptor. Since the compound has two excited states including a localized state and a charge transfer state, the compound achieves fluorescence-delayed fluorescence dual emission; along with the increasing of solvent polarity, fluorescence emission peak displacement and lifetime are constant basically, and delayed fluorescence has distinct red shift while decay lifetime is shortened. Therefore, the derivative can serveas a novel fluorescence polarity sensor which utilizes self-fluorescence emission peak as the internal standard and detects polarity change in environments and organisms according to the simultaneouschange of delayed fluorescence emission and lifetime, and can be used for solution polarity tests.

The invention discloses a carbon quantum dot which is prepared by taking silkworm excrement as a carbon source. The doping atom percentages of N and O are respectively 0.01 to 30 percent and 0.05 to 5percent and the particle size is 3 to 4 nm. A preparation method of the carbon quantum dot comprises the following steps: firstly, mixing the silkworm excrement with a carbonizer and carrying out microwave reaction (100 to 1000W, 2 to 60 minutes) to obtain a reaction solution; secondly, dialyzing the reaction solution in which insoluble impurities are removed and carrying out freeze drying, thusobtaining a finished product. The mass-volume ratio of the silkworm excrement to the carbonizer is (1 g to 1 mL) to (1 g to 30 mL) in the first step; in addition, the microwave reaction needs to be carried out in a state of stirring or rotating. The carbon quantum dot disclosed by the invention has the advantages of nitrogen modification, good water solubility and good light stability; besides, the carbon quantum dot can be stored at room temperature for one year or above, and can be used as a fluorescent probe which has significant response characteristics to the change of excitation wavelength, pH, metal ion concentration, temperature and solvent polarity; the carbon quantum dot provides a broad application prospect for the field of biological detection and imaging in the future.

The invention relates to oligomers of cholic acid, cholate derivatives and amino acids called “foldamers” that undergo conformational changes in response to changes in temperature, solvent polarity, small molecules, metal ions, and pH. The foldamers can be used in self-assembling monolayers, or as environmental probes to detect changes in the environment, or as protective agents useful for protecting labile materials from the environment, or as a controlled delivery system for delivering drugs and other useful agents to specific in vivo or in vitro sites.

The invention relates to a triglyceride and diglyceride fractionation method. The method comprises the steps: with a triglyceride and diglyceride mixed structure lipid as a substrate, adsorbing on Florisil, adding an analytically pure organic solvent, stirring at normal temperature, to obtain high-purity triglyceride, then adjusting the solvent polarity to remove a mixture of triglyceride and diglyceride, and finally utilizing ethyl ether for extracting diglyceride adsorbed on the Florisil and having the purity of more than or equal to 96 mol%. The method has the characteristics of simple process, low stirring temperature during elution, short elution time, less used absorption dosage, high product purity and the like.

The invention belongs to the technical field of natural component extraction and preparation, and relates to a periplaneta americana polypeptide extraction method. The method comprises the following steps of removing most of grease by adopting a solvent polarity progressive increase extraction method, and then removing a small amount of residual grease, solvent residues and pigments by adopting aresin adsorption method. In an obtained polypeptide product, the grease residues and organic solvent residues used in the technological process cannot be detected, the fishy smell in the product is eliminated, the content of the product is increased, and the product quality is greatly improved. The method has relatively good market application prospects and economic benefits.

The invention relates to a method that quadratic general revolving regression and response surface methodology combined with enzymatic reaction to synthesize ferulic monoglyceride. The steps include: (1) selecting three reaction medium solvent according to the solvent polarity; (2) designing different proportions of the reaction media of the three solvent and establishing objective functions according to the quadratic general revolving regression; (3) analyzing the objective functions through the response surface methodology to obtain fourteen reaction media combinations with different proportions; (4) implementing the enzymatic reaction in the different media combinations; (5) comparing the conversion rate of the transesterification reaction and the selective predictive value with the actual measured value and detecting the analysis results. The method can systematically, rapidly and effectively prepare the ferulic monoglyceride and greatly improve the selectivity of the reaction while improving the yield.