Method of refining plamatine from herba fibranreae recisae total ulkuloid and its application

Abstract

A process for preparing the refined palmatine from general fibraurea alkaloid faetures that the principle that different kinds of alkaloid have the difference in pH value and solvent polarity is used for separation or the column photography is used for separation, and the relative refining technique is also used to make its purity be 99.0% or more.

Description

technical field

[0001] The invention relates to a method for refining palmatine, in particular to a method for refining palmatine from total alkaloids of vine vine. Background technique

[0002] Palmatine is also known as Palmatine, African Tetrandine, and Palmatine, and its English name is Palmatine. ) quinozine structure. This is an alkaloid widely found in Berberis genus plants.

[0003] Pharmacological studies have confirmed that palmatine has a broad-spectrum antibacterial effect, and has inhibitory effects on bacteria such as Gram-positive bacteria and Gram-negative bacteria, 12 common pathogenic molds and various viruses including cold viruses. Moreover, palmatine can enhance the phagocytic ability of white blood cells in the body. Clinically, it can be used to treat upper respiratory tract infection, tonsillitis, enteritis, dysentery, genitourinary infection, surgical and gynecological infectious inflammation, leukopenia caused by chemotherapy and radiotherapy, in...