Efficient painless drug for treating local tumor ablation

Abstract

The invention discloses an efficient painless drug for treating local tumor ablation. The efficient painless drug is mixed solution of absolute ethyl alcohol and lauromacrogol, wherein the ratio of lauromacrogol is 0.1-99.9%, and the ratio of absolute ethyl alcohol is 99.9%-0.1% according to the volume fraction. The efficient painless drug for treating local tumor ablation, which is injected into local tumor under guide of an ultrasonic imaging technique, is the mixed solution of absolute ethyl alcohol and lauromacrogol according to the volume ratio of 19 / 1 to 99 / 1; and volume ratio of absolute ethyl alcohol to lauromacrogol preferably is 99 / 1 or 19 / 1; the efficient painless drug for treating local tumor ablation is applied to preparation of the drug for treating ablation by being injected to the tumor under guide of the ultrasonic imaging technique; the sufferer has no adverse reaction such as pain in an operation; and the postoperation color Doppler ultrasonic review finds out that the tumor echo is increased, blood flow signals are obviously reduced, and the indexes of a part of patients with rising alpha fetal protein are obviously reduced by review.

Description

technical field [0001] The invention relates to a drug for local ablation of tumors, which uses absolute ethanol to directly kill tumors and lauromacrogol to destroy tumor blood vessels and induce local immune responses to achieve multi-channel anti-tumor effects, and has no adverse reactions such as pain during the injection process, and is highly effective. Painless anti-tumor advantage. Background technique [0002] Tumor chemical ablation has the advantages of simple operation, mild adverse reactions, and low cost, among which percutaneous ethanol injection (PEI) is the most representative. The main mechanism of PEI treatment is that high-concentration ethanol is injected into the tumor to cause rapid dehydration of tumor cells, protein coagulation, denaturation and necrosis of cancer cells. However, due to the uneven diffusion of the drug after intratumoral injection of pure anhydrous ethanol, multiple injections are required, and some large tumors are difficult to be ...

AI Technical Summary

Problems solved by technology

In some studies, intratumoral injection of lauromacrogol injection has a certain effect on the treatment of uterine fibroids, but the overall curative effect is not good, and there is no report on intratumoral injection of lauromacrogol injection in the treatment of malignant tumors.

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