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Textile multicomponent enhancement structure-gradually degradable ureteral stent tube and preparation method thereof

A technology for ureteral stents and reinforced structures, which is applied in stents, medical science, surgery, etc., can solve the problems of sparse structure and single weaving process, and achieve simple preparation, increased smoothness, excellent axial stretching and flexibility. Effect

Active Publication Date: 2013-07-24
DONGHUA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, the weaving process adopted at home and abroad is single, and the structure is sparse, and it is limited to be used as a fiber reinforcement in combination with other preparation methods.

Method used

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  • Textile multicomponent enhancement structure-gradually degradable ureteral stent tube and preparation method thereof
  • Textile multicomponent enhancement structure-gradually degradable ureteral stent tube and preparation method thereof
  • Textile multicomponent enhancement structure-gradually degradable ureteral stent tube and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Firstly, a PLLA fiber 21 and a PDS fiber 22 are merged into yarn 2 on the doubling machine, and a PGLA fiber is yarn 3, and the two yarns of yarn 2 and yarn 3 are distributed one by one. Pour it onto the spindle of a 16-spindle braiding machine, and weave it in a diamond shape. The take-up ratio of the braiding machine is 5. The yarn is braided on a mandrel with a diameter of 0.60 mm. The total length of the braided tube is 16.0 cm. Figure 2a It is a schematic diagram of the surface of the braided structure; after the braided tube is heat-treated at 120°C for 10.0 minutes, the braided layer is removed from the mandrel to form a bracket tube; Figure 2b for Figure 2a The schematic diagram of the surface of the braided structure after heat treatment, wherein the PDS fibers 22 are fused together to become a PDS film 220 .

[0044] The obtained stent tube had an inner diameter of 0.6 mm, a total length of 16.0 cm, and a tube wall thickness of 0.085 mm. The strength when...

Embodiment 2

[0047] First, a PGLA fiber 41 and a PGA fiber 42 are combined into yarn 4 on the doubling machine, and the yarn 4 is evenly distributed and poured onto the spindles of the 24-spindle knitting machine respectively, and the regular structure is used for weaving. The ratio is 5.4, the yarn is braided on a mandrel with a diameter of 1.64mm, and the total length of the braided tube is 28.0cm. Figure 3a It is a schematic diagram of the surface of the braided structure; after the braided tube is heat-treated at 210°C for 0.3min, the braided layer is removed from the mandrel to form a stent tube; Figure 3b for Figure 3a The schematic diagram of the surface of the braided structure after heat treatment, in which the PGLA fibers 41 are fused together to become a PGLA film 410 .

[0048] The obtained stent tube had an inner diameter of 1.64 mm, a total length of 28.0 cm, and a tube wall thickness of 0.089 mm. The strength when compressing 50% of the diameter of the stent tube is 436...

Embodiment 3

[0051] First, on the doubling machine, a PGLA fiber 52 and a PDS fiber 51 are combined into a yarn 5, and then a PGA fiber 61 and a PDS fiber 51 are combined into a yarn 6, and the yarn 5 and the yarn 6 are two The yarns are poured into the spindles of the 32-spindle braiding machine according to the two-by-one distribution (two yarns 5 and one yarn 6 alternately), and the rhombus structure is used for braiding. The take-up ratio of the braiding machine is 5.8, and the yarn Braided on a mandrel with a diameter of 2.68mm, the total length of the braided tube is 40.0cm, Figure 4a It is a schematic diagram of the surface of the braided structure; after the braided tube is heat-treated at 130°C for 8.0 minutes, the braided layer is removed from the mandrel to form a bracket tube; Figure 4b for Figure 4a The schematic diagram of the surface of the braided structure after heat treatment, wherein the PDS fibers 51 are fused together to become a PDS film 510 .

[0052] The obtain...

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Abstract

The invention relates to a textile multicomponent enhancement structure-gradually gradable ureteral stent tube and a preparation method thereof. The textile-based ureteral stent tube is characterized by comprising a film phase and a fiber phase containing different components, wherein the film phase and the fiber phase are mutually mixed, the mechanical property is enhanced, and the two phases are gradually degraded. The preparation method is characterized by comprising the following steps of: weaving at least two degradable fibrous raw materials with different melting temperatures on a core mold by a weaving structure mixed by different configuration, and melting the components with low melting point in the tube wall fiber materials into film by virtue of temperature in a thermal treatment technology, so that the other fiber components in the tube wall can be tightly and evenly combined to enhance the tube wall of the weaving tube. The ureteral stent tube is simple to prepare, has the excellent axial tensile property and flexibility of a fiber stent, and the excellent mechanical supporting performance of a film material stent tube, and can realize the gradual degraded steps of the film and the fiber successively; and a degradation product is less than 0.1mm<3>.

Description

technical field [0001] The invention relates to a textile multi-component reinforced structure gradually degradable ureteral stent tube and a preparation method thereof, and belongs to the technical field of degradable ureteral stent tube and its preparation. Background technique [0002] In 1967, Zimskind et al. first applied intraluminal technology to retrogradely implant a silicone rubber ureteral stent through a cystoscope, successfully alleviating ureteral obstruction. With a history of more than 40 years, ureteral stents are widely used in urological operations such as upper urinary tract obstructive lesions, nephroureteral calculus, urinary system trauma, and upper urinary tract reconstruction. The main function of a ureteral stent is to keep the ureter open and drain urine into the bladder. The main components of the currently used ureteral stents are non-absorbable polyurethane, silicone rubber, and metal materials, which need to be taken out again after surgery, h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90A61L31/06
Inventor 王璐邹婷黄轶晨尚亚峰王富军谢华林婧周君梅王文祖陈方
Owner DONGHUA UNIV
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