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Huoxiang Zhengqi externally-applied preparation and its preparation method and application

An external preparation, the technology of Huoxiangzhengqi, is applied in the directions of medical preparations with non-active ingredients, medical preparations containing active ingredients, antifungal agents, etc., to achieve the effects of prolonging retention time, improving drug efficacy, and improving curative effect.

Inactive Publication Date: 2013-09-04
CHANGZHOU DEZE MEDICAL SCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After screening and research on medicinal polymer materials and their proportions with Huoxiang Zhengqi, etc., the inventors creatively utilized the advantages of medicinal polymer materials to solve the preparation problem of Huoxiang Zhengqi external preparations, and obtained Huoxiang Zhengqi with stable quality. Xiangzhengqi topical preparation

Method used

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  • Huoxiang Zhengqi externally-applied preparation and its preparation method and application
  • Huoxiang Zhengqi externally-applied preparation and its preparation method and application

Examples

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Effect test

preparation example 1

[0051] Preparation Example 1 The preparation of the pharmaceutical active ingredient of the present invention (hereinafter referred to as liquid medicine):

[0052] According to the proportion of Chinese Pharmacopoeia, weigh 1600g of raw materials Atractylodes atractylodis, 1600g of tangerine peel, 1600g of magnolia officinalis (made from ginger), 2400g of Angelica dahurica, 2400g of Poria cocos, 2400g of Dabupi, 1600g of raw pinellia, 200g of licorice extract, 16ml of patchouli oil, and perilla Leaf oil 8ml spare.

[0053] Magnolia bark was added with 60% ethanol and heated to reflux for 1 hour, and the magnolia bark ethanol solution was taken for later use. Add water to distill Atractylodes atractylodis, tangerine peel, and Angelica dahurica, collect the distillate, filter the distilled aqueous solution, and set aside; decoct the Dabupi skin twice with water, and filter; add water to boil the poria cocos, soak it twice at 80°C, and filter; After soaking in water until the h...

preparation example 2

[0054] Preparation Example 2 The preparation of the pharmaceutical active ingredient of the present invention:

[0055] According to the proportion of Chinese Pharmacopoeia, weigh 1600g of raw materials Atractylodes atractylodis, 1600g of tangerine peel, 1600g of Magnolia officinalis, 2400g of Angelica dahurica, 2400g of Poria cocos, 2400g of Dabupi, 1600g of raw pinellia, 200g of licorice extract, 16ml of patchouli oil, and 8ml of perilla leaf oil. .

[0056] Atractylodes atractylodes, tangerine peel, Magnolia officinalis, and Angelica dahurica were respectively infiltrated according to the liquid extract and extract in the Chinese Pharmacopoeia. Use 60% ethanol as solvent, immerse for 24 hours, carry out percolation, collect the percolation liquid, recover ethanol, and prepare the liquid medicine for later use; after poaching poria cocos, warm soak twice at 80°C, the first time is 3 hours, and the second time is 2 hours , to collect the juice; soak the raw pinellia in cold ...

preparation example 3

[0057] Preparation Example 3 The preparation of the pharmaceutical active ingredient of the present invention:

[0058] According to the proportion of Chinese Pharmacopoeia, weigh 1600g of raw materials Atractylodes atractylodis, 1600g of tangerine peel, 1600g of Magnolia officinalis, 2400g of Angelica dahurica, 2400g of Poria cocos, 2400g of Dabupi, 1600g of raw pinellia, 200g of licorice extract, 16ml of patchouli oil, and 8ml of perilla leaf oil. .

[0059] Atractylodes atractylodes, tangerine peel, magnolia officinalis, and Angelica dahurica were extracted twice with 60% ethanol, the alcohol extract was combined, concentrated to an appropriate amount, and concentrated solution 1 was obtained; Poria cocos, Dabupi were decocted twice, combined with decoction, filtered, and extracted Solution 1; raw pinellia was soaked in cold water until it penetrated the heart, and then 136g of dried ginger was added, decocted twice with water, filtered to obtain extract 2; extract 1 and ex...

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Abstract

The invention relates to a Huoxiang Zhengqi externally-applied preparation and its preparation method and application. The externally-applied preparation is a liquid or semi-solid preparation which is prepared from a Huoxiang Zhengqi medicinal active component and medicinal high-molecular materials such as chitosan, polyvinylpyrrolidone and the like according to a certain ratio. The specific dosage form is gelata, ointment, paints, spraying film. The externally-applied preparation can be used to treat diseases such as eczema, hemorrhoid, manus and tinea pedis and the like.

Description

technical field [0001] The invention relates to an external preparation of traditional Chinese medicine and its preparation method and application, in particular to an external preparation of Huoxiang Zhengqi, its preparation method and application. Background technique [0002] The prescription of Huoxiang Zhengqi comes from Huoxiang Zhengqi Powder contained in "Taiping Huimin Heji Bureau Prescription Volume II", which consists of Dabupi, Angelica dahurica, Perilla, Poria, Pinellia Qu, Atractylodes Rhizoma, Tangerine Peel, Magnolia officinalis, Platycodon grandiflorum, Composed of Huoxiang and Licorice; it has the functions of relieving exterior and removing dampness, regulating qi and neutralizing; it is mainly used to treat exogenous wind-cold and internal injury and stagnation of dampness. Modern studies have shown that this product mainly has antiemetic, analgesic, antispasmodic, enhanced cellular immune function and antibacterial effects [Lu Wei, Wu Wenjin. Pharmacolog...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K47/30A61P17/02A61P31/22A61P17/00A61P31/10A61P17/04A61P15/02A61P11/00A61P11/02A61P37/08A61P9/14
Inventor 吴巍滕厚雷
Owner CHANGZHOU DEZE MEDICAL SCI CO LTD
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