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Pharmaceutical use of compositions containing carbonaceous materials and active particles

A technology of carbonaceous materials and active particles, applied in the direction of medical preparations containing active ingredients, drug combinations, inorganic active ingredients, etc., can solve problems such as toxic side effects and drug resistance, affecting the selection of disease treatment drugs, and affecting the cure of diseases, etc. To achieve the effect of inhibiting infection

Active Publication Date: 2015-10-28
FENG CHIA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, during the entire treatment process, most patients may have toxic side effects of the drug, such as: dizziness, bitter mouth, long tongue coating, abdominal distension, dull taste, nausea, diarrhea; Easy to produce non-compliance with treatment, which affects the cure of the disease
On the other hand, long-term use of antibiotics by patients may cause Helicobacter pylori to develop drug resistance. The result of drug resistance not only affects the cure of the disease, but also affects the choice of drugs for future disease treatment
[0004] In summary, the drugs used to treat Helicobacter pylori infection have problems of side effects and drug resistance, so it is indeed necessary to develop a variety of different drugs to provide a variety of options for the treatment of Helicobacter pylori infection

Method used

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  • Pharmaceutical use of compositions containing carbonaceous materials and active particles
  • Pharmaceutical use of compositions containing carbonaceous materials and active particles
  • Pharmaceutical use of compositions containing carbonaceous materials and active particles

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0023] Provide a polyacrylonitrile activated carbon fiber cloth, its properties are as follows: cloth weight is 70g / m 2 , warp and weft density is 16 threads / in, BET specific surface area is 1,630m 2 / g, the density is 2.09g / m 3 , the carbon content is 85wt%, and the silver content is 0wt%.

[0024] Under a vacuum environment, the fiber cloth was soaked in a 0.1M silver nitrate aqueous solution (pH 3.8) for 5 hours, so that the silver ions were reduced to silver pieces attached to the fiber cloth. Dry the fiber cloth with the silver nub attached to remove any remaining moisture.

[0025] The dried fibers were placed in a high-temperature furnace with a temperature of 400° C. and filled with nitrogen for 90 minutes, so that the silver pieces were cracked into silver particles dispersed and attached to the fiber cloth.

[0026] The fiber cloth with silver particles is ground, pulverized and sieved to obtain an activated carbon fiber (such as figure 2 As shown, the overall c...

preparation example 2

[0029] In a vacuum environment, the polyacrylonitrile-based activated carbon fiber cloth used in Preparation Example 1 was soaked in a silver nitrate aqueous solution (pH3.8) with a concentration of 0.1M for 5 hours, so that the silver ions were reduced to become attached to the fiber cloth. silver nugget. Dry the fiber cloth with the silver nub attached to remove any remaining moisture.

[0030] The dried fibers were placed in a high-temperature furnace with a temperature of 400° C. and filled with nitrogen for 90 minutes, so that the silver pieces were cracked into silver particles dispersed and attached to the fiber cloth.

[0031] Wash the fiber cloth with silver particles with water at a flow rate of 4.5 liters / min for 120 hours to remove the silver particles not attached to the fiber cloth. Dry the cleaned fiber cloth.

[0032]The dried fiber cloth is ground, pulverized and sieved to obtain an activated carbon fiber loaded with silver particles (the overall structure o...

preparation example 3

[0035] Provide a phenolic activated carbon fiber felt, its properties are as follows: the felt weight is 100g / m 2 、BET specific surface area is 1,420m 2 / g, the density is 2.032g / m 3 , the carbon content is 85wt%, and the silver content is 0wt%.

[0036] Under a vacuum environment, the fiber felt was soaked in a 0.001M silver nitrate aqueous solution (pH6.4) for 5 hours, so that the silver ions were reduced to silver lumps attached to the fiber felt. Dry the fiber mat with the silver block attached to remove any residual moisture from it.

[0037] The dried fiber mat was placed in a high-temperature furnace with a temperature of 400° C. and filled with nitrogen for 90 minutes, so that the silver block was cracked into silver particles dispersed and attached to the fiber mat.

[0038] The fiber mat with silver particles is ground, pulverized and sieved to obtain an activated carbon fiber loaded with silver particles (the overall structure of silver particles and activated ca...

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Abstract

The invention provides an application of a composition used for preparing medicines used for treating or preventing Helicobacter pylori infection. The composition comprises a carbon material and active particles which is loaded on the carbon material and whose material is silver, gold, aluminum, zinc, copper or titanium dioxide.

Description

technical field [0001] The invention relates to the use of a composition containing carbonaceous material and active particles for preparing medicine. The composition has the effect of inhibiting Helicobacter pylori infection, and can be used for treating or preventing Helicobacter pylori infection. Background technique [0002] Helicobacter pylori (scientific name: Helicobacter pylori) is a Gram-negative microaerobic bacterium that mainly parasitizes various regions in the human stomach or duodenum. Since scientists such as R.Warren and B.Marshall isolated Helicobacter pylori from the patient's stomach in 1982, many literature reports have confirmed that the infection of Helicobacter pylori can cause gastroenteritis, and even more seriously cause gastric ulcers, severe Duodenal ulcer, gastric lymphoma, or gastric cancer and other diseases. The World Health Organization (WHO) declared Helicobacter pylori as a class I carcinogen for gastric cancer in 1994. [0003] At pres...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/44A23L1/29A23L2/52A61P1/04A61P31/04A61K33/38A61K33/30A61K33/34A61K33/24A61K33/06A23L33/00
Inventor 柯泽豪
Owner FENG CHIA UNIVERSITY