Drug for treating the asthma disease and preparation method thereof

A technology for asthma and medicine, applied in the field of medicine for the treatment of asthma and its preparation, can solve the problems of weakening labor ability, difficult to obtain a radical cure, and lowering the quality of life, and achieves stable and controllable quality, reduced production cost, and convenient use. Effect

Inactive Publication Date: 2013-11-20
XINJIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease is prone to recurrent attacks, which can lead to complications such as chronic obstructive pulmonary disease, emphysema, pulmonary heart disease, heart failure, respiratory failure, etc., seriously endangering people's health, weakening labor ability, reducing quality of life, and difficult to be cured
Because antibiotics have no therapeutic effect on asthma, repeated use of antibiotics is likely to cause drug resistance. At present, hormones and theophylline drugs, which are mainly used to inhibit inflammation, are commonly used to control asthma symptoms. Although they have certain curative effects, long-term use will cause bone Quality loose, high blood pressure, diabetes and other side effects

Method used

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  • Drug for treating the asthma disease and preparation method thereof
  • Drug for treating the asthma disease and preparation method thereof

Examples

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Effect test

Embodiment 1

[0014] Example 1, the medicine for treating asthma is obtained by the following method, the extract powder of Sorbus tianshanensis and auxiliary materials are mixed in a weight ratio of 1:1 to 3:1 to obtain a mixed material, and the volume percentage is added to the mixed material 85% to 95% ethanol is used as a wetting agent, and the amount of the wetting agent added is 1 milliliter to 3 milliliters of wetting agent per gram of the mixed material to bond the mixed material and the wetting agent together to obtain a soft material. The soft material is extruded and granulated through a 20-mesh sieve, and after granulation, it is vacuum-dried at 50°C to 60°C until the moisture content in mass percent is less than 2%, and then granulated through a 20-mesh sieve to 80-mesh sieve to obtain a drug for treating asthma .

Embodiment 2

[0015] Example 2, the medicine for the treatment of asthma is obtained as follows, the Sorbus tianshanensis extract powder and auxiliary materials are mixed in a weight ratio of 1:1 or 3:1 to obtain a mixed material, and the volume percentage is added to the mixed material 85% or 95% ethanol is used as a wetting agent, and the amount of the wetting agent added is 1 milliliter or 3 milliliters of wetting agent per gram of the mixed material to bond the mixed material and the wetting agent together to obtain a soft material. The soft material is extruded and granulated through a 20-mesh sieve, and after granulation, it is vacuum-dried at 50°C or 60°C until the moisture content in mass percent is less than 2%, and then granulated through a 20-mesh or 80-mesh sieve to obtain a drug for treating asthma .

Embodiment 3

[0016] Embodiment 3, as the optimization of the above-mentioned embodiment, the extract powder of Sorbus tianshanensis of embodiment 3 is obtained according to the following steps: the first step, the branches and leaves of Sorbus chinensis and Sorbus tianshanensis fruit are 1:1 to 3 by weight : 1 mixed to obtain mixed medicinal materials, adding volume percentage to the mixed medicinal materials is 40% to 50% ethanol to extract 3 times, the time of each extraction is 2 hours to 4 hours, and the temperature of each extraction is 40 ℃ to 100 ℃ , the addition of ethanol in the mixed medicinal materials during each extraction is that 10 liters to 20 liters of ethanol with a volume percentage of 40% to 50% is added in every kilogram of mixed medicinal materials; the second step is to obtain the extract by filtering after each extraction is completed. The extracts obtained each time are combined to obtain a blended solution, and the blended solution is concentrated to 8% to 15%...

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Abstract

The invention relates to the technical field of drugs for treating an asthma disease and relates to a drug for treating the asthma disease and a preparation method thereof. The drug for treating the asthma disease is prepared according to the method which comprises the following steps of: uniformly mixing sorbus tianchanica extractum powder and an auxiliary material in a weight ratio of 1:1 to 3:1 to obtain a mixed material; adding 85-95vol% of ethanol as a wetting agent to the mixed material. The drug disclosed by the invention is based on the abundant resources of a folk peculiar natural plant drug-sorbus tianchanica with definite asthma treatment pharmacological action in Sinkiang, takes the advantages of national traditional medicines and folk traditional medicines especially, is prepared according to a modern advanced pharmaceutical technology by steps of adding the wetting agent to the sorbus tianchanica extractum powder and the auxiliary material, granulating through a wet method, drying and refining granules. The drug has definite treatment effect, stable and controllable quality, high safety and low toxicity, is convenient to use, and can be put into industrial production so as to reduce the production cost.

Description

technical field [0001] The invention relates to the technical field of drugs for treating asthma, and relates to a drug for treating asthma and a preparation method thereof. Background technique [0002] Asthma is a common disease of the respiratory tract, which refers to chronic airway inflammation involving a variety of degenerated cells, such as eosinophils, mast cells, T cells, airway epithelial cells, and cell components. The clinical manifestations of asthma patients are paroxysmal wheezing, shortness of breath, chest tightness or coughing and other symptoms. A small number of patients may also have chest pain as the main manifestation. The disease has a high incidence worldwide. There are about 300 million asthma patients worldwide. About 30 million patients. The disease is prone to recurrent attacks, which can lead to complications such as chronic obstructive pulmonary disease, emphysema, pulmonary heart disease, heart failure, respiratory failure, etc., seriously e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P11/06A61K127/00A61K131/00A61K135/00
Inventor 常军民刘玉花何家伟向阳
Owner XINJIANG MEDICAL UNIV
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