90 results about "Asthma copd" patented technology

The present invention relates to methods and compositions for the prevention and treatment and prevention of immune system disorders, including cancer, AIDS, asthmatic disorders, autoimmune diseases, organ transplant rejection and chronic viral diseases such as HCV or HBV infections. The therapeutic methods of the invention comprise administering molecules that modulate the activity of 8F4, thereby modulating costimulation of T cells. The present invention further provides monoclonal antibodies against the 8F4 molecule and hybridoma cells which produce said monoclonal antibodies. Pharmaceutical compositions comprising molecules that modulate the activity of 8F4 are also provided.

The invention discloses a patch for treating bronchial asthma of children. The patch comprises a medicinal composition, and the medicinal composition is prepared from the following components in part by weight: 10 to 30 parts of Chinese ephedra, 10 to 30 parts of white mustard seed, 1 to 15 parts of clove, 15 to 45 parts of Japanese ardisia, 5 to 20 parts of wild ginger and 10 to 30 parts of ginger. Clinical tests show that the patch do not cause any reverse reaction and have obvious curative effect; after patients use the patch, the bodies of the patients are obviously strengthened, which means that the product has the effect of enhancing the immunity of organisms. When the Xiangmahanchuan patch is applied to acupuncture points, the patch can achieve the effects of obviously treating asthma, enhancing the body of children suffering asthma and preventing the recurrence of asthma.

The invention relates to the technical field of loose filling materials for furniture coverings and in particular relates to a far infrared hollow tube as well as a preparation method and application of the far infrared hollow tube. The far infrared hollow tube is prepared from a resin component and a functional component, wherein the resin component is selected from polyethylene and polypropylene; the functional component is selected from far infrared ceramic powder, an antibacterial agent and negative ion powder; the adding amount of the functional component is 0.1 weight percent to 10 weight percent and the sum of the weight percent of all the components is 100 percent. Functional filling is innovatively added into polyethylene and polypropylene resin so that a prepared plastic tube can emit far infrared rays and release negative ions; the plastic tube is filled as a filling material and can be used for improving blood circulation of human bodies and improving sleep; the air permeability is good and fresh air in a pillow can keep circulating, moisture is emitted in real time and the pillow keeps dry; the plastic tube has antibacterial and mite-proof effects and is especially suitable for people with allergic rhinitis, respiratory diseases and asthma to use; the far infrared hollow tube is convenient to clean can be repeatedly washed, and the performances of the far infrared hollow tube are not influenced.

The invention relates to a medicinal composition for treating children's bronchial asthma, which is prepared from the following raw materials together with pharmaceutically acceptable carrying agents: Chinese ephedra 10g, cassia twig 15g, asarum herb 5g, safflower 15g, pinellia tuber 10g, dried orange peel 10g, tendril-leaved fritillary bulb 5g, peach kernels 10g, gecko 2 pieces, licorice root 10g, chlorpheniramine 0.12g and apozepam 10mg.

A composite medicine in the form of injection or orally taken solid or liquid for treating asthmatic chronic bronchitis, acute bronchal asthma, lung infection, pneumonia, pneumonectasis, cardiogenic asthma, pulmonary tuberculosis, silicosis, etc is prepared from indianmulberry root or its extract and picrorhiza rhizome or its extract. Its preparing process is also disclosed.

The invention relates to a drug for curing asthma, which is prepared by the following bulk drugs including 5-10g of Chinese ephedra, 5-15g of yam rhizome, 5-15g of earthworm, 5-9g of schisandra fruit and 5-15g of liquorice. The provided drug for curing asthma belongs to a traditional Chinese medicine preparation, and the pharmacological experiment and the clinical experiment show that the drug can treat both principal and secondary aspect of diseases, has the characteristics of fast effect, good therapeutic effect and no toxic side effect and is convenient for taking and carrying.

The invention relates to a medicine [Xiaoling (in pinyin) Soup 12#] for treating tracheitis, rhinitis, pharyngitis, pneumonectasis, pulmonary heart diseases and asthmatic diseases, which comprises ganoderma, ginseng, herba epimedii, radix astragali, giant knotweed, rhizoma gastrodiae, herba houttuyniae and liquorice. The medicine for treating the tracheitis, the rhinitis, the pharyngitis,the pneumonectasis, the pulmonary heart diseases and the asthmatic diseases is made of pure traditional Chinese medicines and has numerous advantages of good curative effect, small side effect, short course of treatment, and the like; at the same time, the formula of the medicine can be simultaneously used for treating a plurality of diseases, has the effects of being antibacterial and antiphlogistic, relieving a cough, stopping asthma, decreasing blood pressure and blood sugar, calming, soothing nerves, promoting blood circulation, alleviating pain, killing viruses and improving the immunity of a human body, and further has the actions of treating tumors, pronging life and preventing ageing. The medicine has the characteristics of quick effect and high cure rate for the treatment of bronchitis, bronchiectasis, allergic rhinitis, nasosinusitis, the pharyngitis, the pneumonectasis, the pulmonary heart diseases and the asthmatic diseases.

The invention relates to a traditional Chinese medicine patch for the prevention and early-stage curing of bronchial asthma, and the treatment of a plurality of respiratory diseases and megrims, characterized in that the traditional Chinese medicine patch comprises, based on the weight percentage, 57 to 70 % of peach seed, 12 to 25 % of cape jasmine, 6 to 8 % of almond, and 5 to 10% of pepper. The invention has the advantages that the traditional Chinese medicine patch is mainly used for treating bronchial asthma, can cure the bronchial asthma of children at the age of below 12, and can be used in the outbreaking or catabatic period. The traditional Chinese medicine patch has the efficacy of diminishing inflammation, invigorating blood circulation, removing blood stasis, clearing away cold, relieving cough and calming panting. The traditional Chinese medicine patch can promote the synthesis of the alveolar surfactant, protect the pulmonary function to improve the lesion tissues, and can stimulate the proliferation of blood vessel endothelial cells to restore the endangium. The traditional Chinese medicine patch has the antiallergic effect, can inhibit the antiserum reaction of allergic antibody of the skin, reduce the pigment seepage and alleviate the airway obstruction. The traditional Chinese medicine patch can enhance the proliferation and conversion of T lymphocyte of spleen of a body, and improve the autoimmunity.

The invention relates to the application of title total saponins of Rehmannia glutinosa in preparing medicinal composition for treating and preventing asthma and allergic diseases. The title total saponins of Rehmannia glutinosa have anti-inflammatory and anti-allergic effect with low toxicity and adverse effect. The invention also discloses the method for preparing title total saponins of Rehmannia glutinosa. The method comprises subjecting the aqueous solution of Rehmannia glutinosa extract to active carbon adsorption, washing with water or organic solvent with low concentration to remove sugar and other impurity, eluting with organic solvent with high concentration, collecting eluate, and concentrating till dry.

A health-care beverage for the patients of bronchitis and asthma is prepared from water melon, ginger and jujube, vinegar, honey, citric acid and essence through proportional mixing and sterilizing.

The invention discloses a Chinese herbal compound volatile oil part for treating asthma and a preparation method thereof. The Chinese herbal compound volatile oil part is extracted by steam distillation from a crude drug which is made from licorice, Chinese ephedra, bitter apricot kernel, pinellia tuber, gypsum, tea bust and Chinese magnolivine fruit according to certain weight proportion by parts with the yield of 0.17%. The Chinese herbal compound volatile oil part has the advantages of simple preparation process, good reproducibility and low cost. Pharmacological tests prove that the Chinese herbal compound volatile oil part of the invention can obviously prolong the incubation period of asthma in animals, reduce the responsiveness of asthma airway, improve the ethological sign of asthma, obviously decrease EOS in BALF, inhibit the aggregation of main inflammatory cells EOS in lung tissues, obviously inhibit the level of inflammatory factors IL-4 and IL-5 in serum, improve the level of IFN-Gamma in serum, and regulate the balance relationship of Th1 / Th2, therefore, the Chinese herbal compound volatile oil part of the invention is ideal for preparing the medicine for treating asthma.

The invention provides a use of a slug protein in preparing medicines for treating asthma and belongs to the technical field of the medicines. In order to solve the problems of the existing medicines for treating asthma, the slug protein is combined with appropriate medical accessories in use. The invention provides a new use of the slug protein in preparing the medicines for treating the asthma. Designed for special asthma symptoms, the content of the extracted and purified slug protein is 92-99%, and then the slug protein of the purity is prepared into medicines in various forms; the medicines are clear in ingredients, good in consistency, controllable in quality, good in curative effect on asthma symptoms and convenient to use.

The invention relates to the technical field of drugs for treating an asthma disease and relates to a drug for treating the asthma disease and a preparation method thereof. The drug for treating the asthma disease is prepared according to the method which comprises the following steps of: uniformly mixing sorbus tianchanica extractum powder and an auxiliary material in a weight ratio of 1:1 to 3:1 to obtain a mixed material; adding 85-95vol% of ethanol as a wetting agent to the mixed material. The drug disclosed by the invention is based on the abundant resources of a folk peculiar natural plant drug-sorbus tianchanica with definite asthma treatment pharmacological action in Sinkiang, takes the advantages of national traditional medicines and folk traditional medicines especially, is prepared according to a modern advanced pharmaceutical technology by steps of adding the wetting agent to the sorbus tianchanica extractum powder and the auxiliary material, granulating through a wet method, drying and refining granules. The drug has definite treatment effect, stable and controllable quality, high safety and low toxicity, is convenient to use, and can be put into industrial production so as to reduce the production cost.

The invention relates to one natural therapy, relates to the field of traditional Chinese medicine science, and particularly relates to an externally-applied method of a traditional Chinese medicine capable of treating pediatric asthma. The externally-applied method comprises the steps of selecting 30 g of high-quality semen brassicae, 30 g of rhizoma corydalis, 15 g of gansui root, 15 g of herba asari and 9 g of earthworm, making the above raw materials into medicine cakes; incorporating 6 g of clove and 6 g of cortex cinnamomi; applying the medicine at three pairs of points of Dingchuan, Feishu and Gaomang; applying the medicine for 2 hours every time; during a diseased period, applying the medicine one time ever other five days and applying the medicine for 3 times in total; and during a remission period, applying the medicine one time ever other seven days and applying the medicine for 5 times in total. The externally-applied method is simple and practical in treating the pediatric asthma, causes small pains, has the advantages of wide application symptoms, good curative effect, low cost and few side effects, and is a promising method of the natural therapies. Therefore, the externally-applied method has prospects of entering in homes, moving toward the world and benefiting the humanity.

The present invention relates generally to compositions and their use in the treatment and / or prophylaxis of inflammatory conditions in an animal such as a mammal, including a human. More particularly, the compositions of the present invention comprise agents which modulate the level of expression of genes or the level of activity of gene products involved in eliciting an inflammatory response and in particular an asthmatic condition. The present invention also provides methods for identifying additional agents which interact with selected target genes or target gene products, the regulation of which, provide useful means for treating and / or preventing the development of an inflammatory condition such as asthma. Furthermore, methods of treatment and / or prophylaxis in an animal such as a mammal including a human, by the administration of a composition of the present invention, are provided.

A composite medicine in the form of injection or orally taken solid or liquid for treating asthmatic chronic bronchitis, acute bronchal asthma, lung infection, pneumonia, pneumonectasis, cardiogenic asthma, pulmonary tuberculosis, silicosis, etc is prepared from epimedium or its extract, picrorhiza rhizome or its extract, and houttuynia or its extract. Its preparing process is also disclosed.

The invention relates to an oral compound pharmaceutic preparation for treating asthma, which contains tranilast shown as the formula (I) and salbutamol sulfate shown as the formula (II) or other pharmaceutically allowed active ingredients. The invention also relates to the application of compounds shown as formulas (I) and (II) or pharmaceutically allowed salts thereof in the preparation of an oral therapeutical agent for treating asthma.

The invention provides a wheat germ agglutinin modified salmeterol xinafoate chitosan nanoparticle preparation and a preparation method thereof, relating to the technical field of medicines. In the invention, an ion cross-linking method is used for preparing salmeterol xinafoate chitosan nanoparticles; and by utilizing the characteristic that the alveolar epithelium has specific sugar receptor N-acetyl glucosamine, wheat germ agglutinin modified salmeterol xinafoate chitosan nanoparticles are prepared, so that the specific sugar receptor N-acetyl glucosamine of the alveolar epithelium can be combined through the wheat germ agglutinin to enable the salmeterol xinafoate chitosan nanoparticles to have the targeting property of guiding the alveolar membrane. In-vitro sugar-binding test results show that the wheat germ agglutinin modified salmeterol xinafoate chitosan nanoparticles have the advantage of guiding the alveolar membrane, thus the administration dosage can be lowered, and the toxic side effect can be reduced; and by the slow release of the medicament, the effective concentration maintaining time of the medicament in the lung is long, thereby enhancing the treatment effect. The preparation provided by the invention can be used for preparing medicaments for treating asthma, chronic bronchitis or chronic obstructive pulmonary disease.

The invention discloses a traditional Chinese medicine preparation for treating bronchitis and asthma. The traditional Chinese medicine preparation is characterized by being prepared from the following raw material medicines in parts by weight: 6-15 parts of dried tangerine or orange peel, 5-10 parts of peucedanum praeruptorum, 9-12 parts of ark shell, 10-15 parts of liquorice, 6-9 parts of silkworm larvae, 5-10 parts of oyster plant inflorescence, 8-12 parts of honey-fried ephedra, 6-15 parts of rhizoma nelumbinis and 5-10 parts of gallnut. The traditional Chinese medicine preparation has notable curative effect on trachitis and asthma caused by insufficiency of both the spleen and the kidney and has the effects of clearing lung and eliminating phlegm as well as relieving cough and asthma, at the same time improves the functions of tonifying qi and kidney as well as soothing the liver and activating the blood, and is free of toxic or side effect as the materials are all traditional Chinese medicinal materials; the medicines are easy to obtain, the medicines are low in cost, and the burden of patients can be alleviated.

The invention discloses a method for preparing a medicament for treating asthma. The method is implemented by the following technical scheme of: shelling gingko, and frying the gingko until brown; slicing pinellia tuber, decocting, and removing decoction dregs; adding alum into the decoction, decocting for 1 hour, and airing; refining common coltsfoot flower with cooked honey and water, stirring uniformly, sealing for 2 hours, and frying over low fire until the fried components are not sticky; refining the root bark of white mulberry with cooked honey and water, stirring uniformly, sealing for 30 minutes, and frying the components over low fire until brown; and boiling the components together with ephedr, liquorice and water for 15 minutes; filtering off the liquor, boiling the liquor with water for 20 minutes; removing decoction dregs; and blending the two liquors uniformly, and taking the combined liquor for several times. By adopting the method, the curative effect of the medicament can be improved remarkably.

The invention relates to a traditional Chinese medicine composition for treating asthma and an application of the traditional Chinese medicine composition. The traditional Chinese medicine compositionconsists of the following raw material medicines in parts by weight: 4.5 parts of tortoise-plastron glue, 4.5 parts of turtle shell glue, 3 parts of deer-horn glue, 6 parts of aconitum carmichaeli, 15 parts of negundo chastetree fruits, 9 parts of prepared rehmannia roots, 6 parts of cocklebur fruits, 15 parts of raw milkvetch roots, 7.5 parts of fried codonopsis pilosula, 9 parts of herba epimedii, 6 parts of curculigo orchioides, 4.5 parts of spina gleditsiae, 15 parts of radix rehmanniae recen, 15 parts of pearl shell, 15 parts of dandelions, 15 parts of oldenlandia diffusa, 7.5 parts of plaster, 6 parts of baked ginger and 4.5 parts of honey-fried licorice roots. The formula not only has the functions of warming yang, diffusing lung, dispelling cold, tonifying Yin and Yuan Yang, and strengthening Yuan and consolidating asthma due to lung-kidney deficiency, but also can regulate the immune function of a human body, warm Yang, replenish essence, and strengthen healthy qi to help eliminate pathogenic factors. The traditional Chinese medicine composition has the advantages that the curative effect is exact, medication is safe, and experimental results show that obvious abnormity is not found through monitoring of etiologic examinations, liver and kidney functions and electrocardiogram.

The invention provides a theophylline sustained-release tablet and a preparation method thereof, which relate to the technical field of medicine and consist of a tablet core and a coating layer; the preparation method comprises the following steps: ultrafinely pulverize tangerine peel, licorice, and almonds, mix them uniformly, add Prepare suspension A with sterile water; add suspension A to the wet granulator, add animal fat to the wet granulator, stir and shear at room temperature, and process for 5-12 minutes; add tea to the wet granulator Alkali, after mixing for 50-60min, the tablet core is obtained; the polymer of titanium dioxide and polyethylene glycol, beeswax, carnauba wax, and sucrose are added to purified water to make a coating solution; the granules are dried, and the coating solution is added. Coating and drying are performed to obtain theophylline sustained-release tablets. The theophylline sustained-release tablet of the present invention can be released at a constant rate, stable in quality, safe, effective and stable to solve the ailments of asthmatic patients, avoid the toxic and side effects caused by the increased release of theophylline, and better improve the use value of theophylline sustained-release tablet , help to solve the patient's pain.

The invention relates to a special-effect drug for treating asthma, which is composed of a drug I, a drug II and a drug III; the drug I comprises the following components by weight: 0.016g of dead bacillus calmette guerin vaccine, 1.071g of potato starch, 0.3g of aminophylline, 0.001g of ketotifen, 0.005g of dioxopromethazine, 0.025g of levomisole, 0.03g of bromhexine and 0.8g of green tea; the drug II comprises the following components by weight: 1.4g of fructus schisandrae, 1.4g of astragalus and 0.3g of cinnamon; and the drug IIT comprises the following components by weight: 1.2g of radix codonopsis, 1.2g of astragalus, 0.3g of epimedium and 0.4g of gypsum. The special-effect drug disclosed by the invention is prepared on the basis of combination of Chinese and western medicine sciences, has remarkable treatment effect, and treats both symptoms and root causes.

The invention provides a spray inhaler mouthpiece for asthma treatment. The spray inhaler mouthpiece comprises a buccal nozzle and a spherical flow guide cavity, wherein the spherical flow guide cavity comprises an outer spherical wall and a flow guide wall; a return wall toward the inner side of the flow guide wall extends out of the joint of the outer spherical wall and the buccal nozzle; the flow guide wall is self-enclosed to form a main circulation channel; an airflow sandwich channel is formed between the outer spherical wall and the flow guide wall; and a convection channel is formed between the return wall and the flow guide wall. The main circulation channel, the airflow sandwich channel and the convection channel are matched to guide medicine mist, so that the medicine mist discharged from the buccal nozzle is closer to the external temperature, the stimulation of low-temperature medicine mist in temperature is reduced, the condition that the medicine mist is condensed into liquid drops is completely avoided and the mouthfeel is improved. The medicine mist discharged from the airflow sandwich channel is guided into the main circulation channel in the convection channel and meets with a small amount of medicine mist circulating in the main circulation channel to counteract partial impact force, so that the stimulation of the medicine mist in speed is reduced.

The present invention is directed to the identification of a novel repressor located between ˜1.2 kb to ˜1.6 kb from the translation start site of the IFN-λ1 promoter. The present invention provides a method of using siRNAs against ZEB1 (binds to the repressor region) and BLIMP-1 (binds outside the repressor region) and increases the promoter activity of IFN-λ1 (i.e., increases the production of IFN-λ1 protein). siRNAs against ZEB1 mRNA or BLIMP-1 mRNA increase IFN-λ1 gene activity. There is provided a therapeutic application of siRNAs against ZEB1 and BLIMP-1 mRNAs in treating a mammal (including a human) by increasing the production of IFN-λ1 protein that promotes an anti-viral response as well as treats asthma diseases and colon diseases.

The invention discloses a reagent and reagent kit for detecting children asthma based on a GLCCI1 gene rs37969 site and an application. The reagent comprises a PCR reaction system, an SAP reaction system and an iPLEX extension system. The reagent kit comprises the reagent. The reagent is applied to preparation of the reagent kit for predicting the risk that children suffer from the asthma through the steps of performing PCR amplification, performing an SAP reaction, performing iPLEX extension, and performing gene sequencing, wherein if a genotype at the GLCCI1 gene rs37969 site is GG, the risk that the children generate asthma before 6 years old is small, if the genotype is TT, the children are susceptible crowds of the asthma and the risk that the children before 6 years old generate the asthma is increased, after ICS treatment, MMEF improvement or PD20 improvement is small, if the genotype is GT, the risk that the children before 6 years old generate the asthma is increased, and after ICS treatment, MMEF improvement or PD20 improvement is small. The reagent disclosed by the invention can be used for performing early genetics prediction on the generation of the asthma.

The invention provides a Chinese medicinal preparation for treating bronchitis and asthma, wherein the constituents include campanumaea pilosula 35-70g, prepared rhizome of rehmannia 35-70g,ophiopogon root 10-35g, poria cocos wolf 10-35 g, achyranthes and cyathula root 10-35g, wolfberry fruit 10-35g, white atractylodes rhizome 10-35g, schisandra fruit 10-35g.

The invention relates to the technical field of traditional Chinese medicine, and discloses a pharmaceutical composition for treating asthma, the pharmaceutical composition comprises the following components by weight: 2-8 g of ginkgo, 3-12 g of perilla leaf, 6-20 g of ginger, 4-14 g of Poria cocos, 1-9 g of balloonflower root, 8-20 g of dried ginger, 4-14 g of apricot kernel, 2-9 g of dried orange peel, 2-9 g of honey-fried licorice root, 2-18 g of mustard seed, and 10-40 g of Chinese yam. , 3-18 g of cordate houttuynia, and 6-20 g of fried walnut kernel. The traditional Chinese medicine composition has no side effect after being used, embodies whole-body regulation, can enhance the function of each visceral organ after being taken by a patient, has the effects of dispelling wind and eliminating evil, ventilating the lung and promoting the circulation of qi, preventing phlegm from forming and stopping coughing, moistening the lung and relieving asthma, fundamentally treats the asthma, has a remarkable treatment effect on the asthma, is short in treatment course and quick in effect, prevents asthmatic attack or relieves symptoms during acute attack, and has no toxic or side effect. The medicine is exact in curative effect, stable and controllable in quality, safe, low in toxicity, convenient to use and applicable to industrial production, so that the production cost is reduced.

The invention relates to a pharmaceutical composition for treating chronic bronchitis and asthma and a preparation method thereof. The pharmaceutical composition is prepared from Chinese medicine components and Western medicine components, wherein the Chinese medicine components comprise the following active pharmaceutical ingredients in parts by weight: 18-34 parts of Chinese eaglewood, 18-34 parts of common hogfennei root, 12-20 parts of wolfberry fruit, 12-20 parts of radix isatidis, 12-20 parts of exuviae, 15-24 parts of heartleaf houttuynia herb and 15-24 parts of radix ophiopogonis; theWestern medicine components comprise the following active pharmaceutical ingredients in parts by weight: 2.3-3.3 parts of paracetamol and 2.3-3.3 parts of benproperine phosphate. According to the pharmaceutical composition provided by the invention, by adding the reasonable components of Chinese medicines into a Western medicine formula, the toxic and side effects of Western medicines can be suppressed while giving full play to the treatment effect of the Western medicines; the medicinal properties of the medicines are effective and mild, and a contradiction that adopting pure Western medicinecomponents to treat chronic bronchitis and asthma according to an idea of combating poison with poison leads to an adverse result is solved.