Feed additive produced from waste liquid and dregs in pharmaceutical factory and preparation method of feed additive

A feed additive and traditional Chinese medicine waste residue technology, applied in animal feed, animal feed, application, etc., can solve problems such as unstable effect, allergic reaction, drug residue, etc., to improve immunity, avoid negative effects, and reduce emissions.

Active Publication Date: 2013-11-27
吾方(新密市)医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) The problem of drug residues in livestock and poultry products; the human body often ingests low doses of antibiotic residues, which will gradually accumulate in the body and cause lesions in various organs, leading to allergic reactions, immunosuppression, teratogenicity, carcinogenicity, mutagenicity, etc.
Feed antibiotics substitutes that have been used in the breeding industry can be summarized into the following categories: (1) Probiotics are als

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Preparation of culture medium:

[0021] Peptone 3.7%, glucose 4%, salt 0.5%, liver ointment 0.5% kg, drinking water 90.3%. Put the above medium components (except glucose) in quantitative purified water and heat to dissolve them, add glucose, then adjust the pH to 6.5, dispense into 50ml test tubes with 1% calcium carbonate, 1000ml Erlenmeyer flask, 15000ml round In the bottom flask, aliquot 25ml for each test tube, 450ml for each Erlenmeyer flask, and 9000ml for each round-bottom flask. Sterilize at 121°C for 30 minutes, and leave to cool for later use.

[0022] (2) Preparation of liquid culture medium

[0023] The Enterococcus faecalis strain (No. 140623, Latin name: E. faecalis ) Inoculate the above-mentioned test tube culture medium, shake culture at 37°C for 24 hours, then inoculate into Erlenmeyer flask culture medium with an inoculum amount of 2%, shake culture at 39°C for 24 hours, and finally inoculate in round bottom flask culture medium, inoculate The amount ...

Embodiment 2

[0026] (1) Preparation of culture medium:

[0027] Peptone 3%, glucose 3%, salt 0.5%, liver ointment 0.5% kg, drinking water 92%. Put the above medium components (except glucose) in quantitative purified water and heat to dissolve them, add glucose, then adjust the pH to 6.5, dispense into 50ml test tubes with 1% calcium carbonate, 1000ml Erlenmeyer flask, 15000ml round In the bottom flask, aliquot 25ml for each test tube, 450ml for each Erlenmeyer flask, and 9000ml for each round-bottom flask. Sterilize at 121°C for 30 minutes, and leave to cool for later use.

[0028] (2) Preparation of liquid culture medium

[0029] The Enterococcus faecalis strain (No. 140623, Latin name: E. faecalis ) Inoculate in the above-mentioned test tube culture medium, shake culture at 39℃ for 20 hours, then inoculate into Erlenmeyer flask culture medium, the inoculation amount is 5%, shake culture at 39℃ for 24 hours, and finally inoculate into round bottom flask culture medium, inoculate The amount i...

Embodiment 3

[0032] (1) Preparation of culture medium:

[0033] Peptone 4%, glucose 4%, salt 1%, liver ointment 1% kg, drinking water 89%. Put the above medium components (except glucose) in quantitative purified water and heat to dissolve them, add glucose, then adjust the pH to 6.5, dispense into 50ml test tubes with 1% calcium carbonate, 1000ml Erlenmeyer flask, 15000ml round In the bottom flask, aliquot 25ml for each test tube, 450ml for each Erlenmeyer flask, and 9000ml for each round-bottom flask. Sterilize at 121°C for 30 minutes, and leave to cool for later use.

[0034] (2) Preparation of liquid culture medium

[0035] The Enterococcus faecalis strain (No. 140623, Latin name: E. faecalis ) Inoculate in the above-mentioned test tube culture medium, culture with shaking at 38°C for 23 hours, then inoculate into the Erlenmeyer flask culture medium, the inoculation amount is 4%, culture with shaking at 38°C for 22 hours, and finally inoculate the culture medium in a round bottom flask, Th...

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PUM

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Abstract

The invention discloses a method for producing a feed additive from waste liquid and dregs in a pharmaceutical factory. The method comprises the following steps of inoculating an enterococcus faecalis seed solution with viable count of 2.5*10<10>-3.5*10<10>/ml on waste dregs mixed with waste liquid in the pharmaceutical factory, and carrying out solid fermentation under an aseptic condition, wherein the fermentation temperature is 37-39 DEG C, and the fermentation time is 40h-48h, 0.1ml-0.3ml of waste liquid, 0.1ml-0.3ml of enterococcus faecalis seed solution and 0.006g-0.015g of calcium carbonate are added to each gram of waste dregs, the waste liquid is generated in a lactasin fermentation process, and the waste dregs are Chinese medicine waste dregs generated during the production of Xiaoshuan enteric capsules. The feed additive provided by the invention can be taken as a substitute of antibiotic to be applied to breeding industry, can be used for improving the immunity of beasts and birds and reducing the morbidity to lower medicine consumption so as to achieve the effect of reducing the breeding cost, and is capable of promoting the healthy development of breeding industry.

Description

technical field [0001] The invention belongs to the technical field of feed additive production, and in particular relates to a feed additive produced by using waste liquid and residue from a pharmaceutical factory and a preparation method thereof. Background technique [0002] CCTV’s exposure of “18 kinds of antibiotics” in KFC’s “instant chicken” incident left ordinary people dumbfounded. In the eyes of ordinary people, antibiotics are used for curing diseases and are harmful to human body, but in fact, adding antibiotics to feed is very common. matter. [0003] The use of antibiotics in farming can be traced back to the 1940s. In 1946, scholars such as Moore reported that adding antibiotics to feed could significantly increase the daily weight gain of broilers. Until today, antibiotics are still the most effective and stable growth-promoting additives, and feed antibiotics have made an indelible contribution to the rapid development of modern livestock and poultry indust...

Claims

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Application Information

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IPC IPC(8): A23K1/16A23K1/00A23K1/14
Inventor 赵占武张少少赵一品赵晓棠邹吉祥
Owner 吾方(新密市)医疗科技有限公司
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