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81 results about "Drug factories" patented technology

Preparation method by using Chinese medicine residue as cultivation material of edible mushroom pleurotus ostreatus

The invention relates to a preparation method by using Chinese medicine residue as a cultivation material of edible mushroom pleurotus ostreatus, which uses the Chinese medicine residue, banana peels, bran, sawdust and lime as raw materials, and is prepared by crushing, insolating, proportioning the materials and sterilizing; specific steps are as follows: respectively crushing the banana peels, the bran and the sawdust into granules; placing the bran, the sawdust and the Chinese medicine residue outdoors to expose to the sun for sterilizing and dewatering; mixing the insolated bran, sawdust and Chinese medicine residue with the crushed banana peels, and then adding water and mixing with the lime sufficiently and uniformly, sterilizing at high temperature to obtain the cultivation material. The preparation method has advantages as follows: the waste Chinese medicine residue from medicine factories and the banana peels are used for culturing high-quality edible mushrooms, the waste is changed into things of value, the production cost is saved, the cultivation period is shortened, the yield is increased, the mushroom contamination rate is reduced with no poison or harm, the eating is safe, the waste treatment difficulty is resolved without causing pollution, both the environmental purpose and the economic purpose are achieved, the operation is simple, and the industrial production is easy to achieve.
Owner:AOWEI TIANJIN ENVIRONMENTAL PROTECTION TECH

Method and device for treating low-concentration acetic acid wastewater

The invention relates to a method and a device for treating and recovering low-concentration acetic acid wastewater generated in a pharmaceutical factory. Equipment of the whole technical flow mainly comprises a two-stage extraction tower, a stripping tower, an acetic acid treating column and corresponding auxiliary equipment thereof. The method comprises the following steps of: adding the acetic acid wastewater from the top of the two-stage extraction tower, and adding an extracting agent from the bottom of a primary extraction tower at a certain flow velocity to pass through the two-stage extraction tower; making the acetic acid-enriched extraction raffinate obtained by two-stage extraction enter the acetic acid treating column for separation, and obtaining high-purity acetic acid at the bottom of the tower, wherein the extracting agent recovered on the top of the tower can be added into an extracting agent system for recycling; making the aqueous solution which is subjected to two-stage extraction and contains a small amount of extracting agent enter the stripping tower, directly discharging the treated wastewater from the bottom of the tower, and recycling an oil phase of a phase splitter, namely the extracting agent on the top of the tower. Due to the technical treatment, the acetic acid content in the wastewater is less than 100ppm, the purity of the acetic acid is over 99.0 weight percent, and the recovery rate is over 98.0 percent.
Owner:天津市天大北洋化工设备有限公司

Method for preparing sapogenin through chenopodium quinoa willdL seed coat and separation and quantification method of sapogenin

The invention provides a method for preparing sapogenin through chenopodium quinoa willdL seed coat and a separation and quantification method of the sapogenin, and belongs to the technical field of biological product processing. The method for preparing the sapogenin through the chenopodium quinoa willdL seed coat comprises the following steps that firstly, the chenopodium quinoa willdL seed coat, complex enzyme and deionized water are mixed and enzymolyzed to obtain enzymatic hydrolysate; then the enzymatic hydrolysate and ethyl alcohol are mixed, chenopodium quinoa willdL saponin in the enzymatic hydrolysate is extracted through ultrasonic waves, solid-liquid separation is conducted, and a chenopodium quinoa willdL saponin extracting solution is obtained; then the chenopodium quinoa willdL saponin extracting solution and hydrochloric acid are mixed and subjected to acidolysis to obtain acidolysis liquid; and finally, the acidolysis liquid is extracted through petroleum ether to obtain extract liquor, and a solvent in the extract liquor is removed through evaporation, and the sapogenin is obtained. According to the method, the chenopodium quinoa willdL seed coat serves as a raw material to prepare the sapogenin, the natural sapogenin raw material can be provided for a professional pharmaceutical factory, the comprehensive utilization rate and the economic added value of chenopodium quinoa willdL can further be increased, and reuse and sustainable development of resources are facilitated. The invention further provides a method for simultaneous separation and quantification of oleanolic acid and hederagenin in the chenopodium quinoa willdL seed coat through UPLC-MS.
Owner:QINGHAI NORMAL UNIV

GPA planting method of Lycoris aurea

The invention discloses a GPA planting method of Lycoris aurea. Harvested flowers of the Lycoris aurea can be used as raw medicinal materials for extracting galanthamine. The method includes the six main steps of plantation building, propagation method implementation, planting, field management, pest control, and harvesting, processing and storage. By replacing wild resources with artificially-cultivated Lycoris aurea resources, the ecological environment can be effectively projected, water and soil loss can be prevented, and market supply of raw medicinal materials of the galanthamine and clinical medication safety of the galanthamine can be guaranteed as well. Because the overground flowers of the Lycoris aurea are used as the raw medicinal materials for extracting the galanthamine, labor intensity is small, the proportion of labor cost is small, and production cost is low. The standard operating procedure of each production link is worked out for the first time. The content of the galanthamine in the dried flowers, used as the raw medicinal materials, of the Lycoris aurea produced through the method is much higher than that in bulbs used as raw medicinal materials for producing galanthamine in a pharmaceutical factory in the prior art. Lycoris aurea industrialization and GAP standardized artificial cultivation are achieved through the method.
Owner:HUNAN UNIV OF CHINESE MEDICINE

Preparation method of compound organic fertilizer for saline and alkaline land

The invention provides a preparation method of a compound organic fertilizer for a saline and alkaline land, relates to the field of fertilizers, and solves the problems that the water retention capacity is poor, the action time is short, and and long-acting and long-lasting treatment cannot be realized in the conventional organic fertilizer for a saline and alkaline land. The organic fertilizer includes 20-25 parts of excrements of people and livestocks, 35-40 parts of plant straws, 6-8 parts of bentonite, 5-8 parts of potassium fulvic acid, 8-10 parts of humic acid, 7-10 parts of porous light-weight volcanic rock, 10-15 parts of pharmacy leftovers from a pharmaceutical factory, 9-12 parts of a compound water-retaining agent, 3-5 parts of a sandy soil adhesive, 1-2 parts of bacillus subtilis, 1-2 parts of arbuscular mycorrhizal, 1-2 parts of trichoderma harzianum, 1-2 parts of salt-tolerance rhodopseudomonas capsulata, 1-2 parts of jelly bacillus, 1-2 parts of phosphate solubilizing bacteria, 1-2 parts of potassium bacteria and 1-2 parts of saccharomycetes. According to the invention, the soil structure of the saline and alkaline land is effectively improved, the fertility is improved, the saline and alkaline is reduced, the soil water retention capacity is improved, accumulation of salt is prevented, and the action is long-lasting.
Owner:吉林省新农科生态农业科技有限公司

Cement kiln harmless pharmaceutical factory waste residue co-processing method

The invention discloses a cement kiln harmless pharmaceutical factory waste residue co-processing method, and relates to the technical field of waste water and waste residue processing. The method comprises the following steps: waste residues are injected into airtight waste residue storage tanks; bulk calcined lime in a storage shed is broken and stored; the broken calcined lime and the waste residue are added into a digestion device for digestion to obtain a digestion object, wherein the moisture content of the digestion object is smaller than or equal to 20%; the digestion object is placed into an airtight digestion object storage tank for storage and standby use; the waste residue storage tanks and the digestion object storage tank are provided with gas collection devices; the digestion object and raw materials for cement production are mixed for compounding, wherein the mass fraction of the digestion object is 20-80%, and the mass fraction of the raw materials for cement production is 80-20%; and the materials and gases collected by the storage tanks are fired into cement clinkers which conform to national standards under the temperature of 1350-1500 DEG C by using a cement production line, and exhaust gases after processing the waste residues by a cement kiln conform to the national standards. The cement kiln harmless pharmaceutical factory waste residue co-processing method is simple, low in cost and environment-friendly.
Owner:HEBEI BUILDING MATERIALS IND DESIGN & RES INST

Acid-resistant, hydrogen-sulfide-resistant and wear-resistant flexible corrosion prevention coating and preparation method thereof

The invention discloses an acid-resistant, hydrogen-sulfide-resistant and wear-resistant flexible corrosion prevention coating which comprises a component A and a component B. The component A comprises, by weight, 20-50 parts of resin, 5-20 parts of polyvinyl butyral, 20-30 parts of mixed solvent, 2-20 parts of ethyl alcohol, 1-5 parts of inorganic-organic anti-rust pigment, 1-5 parts of methyl oleate, 1-5 parts of a wetting agent, 5-20 parts of zinc phosphate and 6-25 parts of hollow ceramic; the component B is composed of triethylene diamine, H1 and H2 according to the mass ratio of (8-10): 1: 2, wherein the H1 and the H2 are from waste liquid of a pharmaceutical factory, and the mass ratio of the component A to the component B is 20: (1-20): 2. By means of the acid-resistant, hydrogen-sulfide-resistant and wear-resistant flexible corrosion prevention coating, the problem of hydrogen sulfide corrosion is effectively solved, the H1 and the H2 from waste liquid of the pharmaceutical factory are added, excellent effects of resisting to naphthenic acid, resisting to hydrogen sulfide corrosion and resisting to water corrosion are achieved, the coating can have acid-resistant, wear-resistant and corrosion-resistant performance, organic inhibitor is combined to the surface of an inorganic material, release of corrosion inhibitor is controlled, and the effect of long-term effectiveness is achieved.
Owner:DAQING CITY HUAYU PETROLEUM MASCH MFG CO LTD

Preparation method of environment-friendly odorless organic fertilizer

The invention discloses a preparation method of an environment-friendly odorless organic fertilizer. The raw materials of the organic fertilizer comprise 30-40 parts of corn straw, 20 to 30 parts of corn coating, 10-20 parts of peanut shells, 10-20 parts of soybean shells, 5-10 parts of waste mushroom cultivation soil, 5-10 parts of sugarcane peels, 5-10 parts of pineapple peels, 5-10 parts of shaddock peels, 5-10 parts of astragalus membranaceus decoction dregs, 2-8 parts of chicken manure, 20-30 parts of kaolin, 20-30 parts of straw ash, 5-10 parts of urea and 20-30 parts of water. The proportion of each component is strictly controlled; nutrients in the organic fertilizer can be improved; astragalus membranaceus decoction dregs are waste decoction dregs produced in pharmaceutical factories; the sugarcane peels, the pineapple peels and the shaddock peels are used as the raw materials, so that the growth of plants is facilitated; a large number of organic substance environment-friendly raw materials are adopted, the production cost is relatively low; and deodorization treatment is performed in a fermentation process, so that the organic fertilizer is odorless and more environment-friendly on the premise of ensuring nutritional ingredients.
Owner:安徽荣丰生物能源科技有限公司

Mechanical type refrigerating cold trap system for sewage source of pharmaceutical factory

The invention discloses a mechanical type refrigerating cold trap system for a sewage source of a pharmaceutical factory, and relates to the technical field of pharmaceutical factory cold trap separation. The system mainly comprises a sewage source refrigerating cold trap system, a jacket type ice melting system and an excessive cold recycling system, wherein a refrigerant working medium loop in the sewage source refrigerating cold trap system and a circulating water loop in the jacket type ice melting system separately define a closed-type cycle; an ice melting cold water pipeline in an excessive cold recycler is connected to a cold trap and a pharmaceutical factory sewage tank; and a condensing gas pipeline of the excessive cold recycling system is connected to the cold trap and the excessive cold recycler. The sewage source refrigerating cold trap system adopts pharmaceutical factory sewage with relatively stable flow as a condenser coiled tube side heat exchange medium, and can improve system operation stability and operation efficiency; a refrigerating system adopts two-stage compression, and can meet gas trap temperature requirements of different gases; the jacket type ice melting system recycles heat at the high-temperature condenser coiled tube side for removing ice blockage for the cold trap; and the excessive cold recycler can effectively recycle cold amount of condensed gas and ice molten water.
Owner:EAST CHINA JIAOTONG UNIVERSITY

Adoptive-immunity cell for expressing recombinant T alpha 1 and preparation method and application of adoptive-immunity cell

InactiveCN107034196ASolve the disadvantages of short half-lifeAvoid allergiesDigestive systemAntinoxious agentsHalf-lifeGenetic engineering
The invention discloses an adoptive-immunity cell for expressing recombinant thymosin alpha 1 and a preparation method and application of the adoptive-immunity cell. The adoptive-immunity cell is a human-derived immune cell, and the recombinant thymosin alpha 1 expressed by the adoptive-immunity cell comprises a signal peptide and thymosin alpha 1. The human-derived secreting signal peptide is connected to the amino terminal of the recombinant thymosin alpha 1, the encoding gene of the recombinant thymosin alpha 1 is used to transfect the adoptive-immunity cell through the genetic engineering technology, the recombinant thymosin alpha 1 can be continuously and stably expressed after the adoptive-immunity cell is transfused back into the body of a user, and a 'miniature cell pharmaceutical factory' effect is achieved. Accordingly, the recombinant thymosin alpha 1 can be stably expressed in the body of the user for a long time by using the adoptive-immunity cell as the carrier cell, and the defects that the thymosin alpha 1 is short in half-life period and high in preparation purity requirement, needs frequent injection causing inconvenience of patients, and the like are overcome.
Owner:新钥(南京)生物科技有限公司

Sales prediction method and system capable of elastically adapting to noise

PendingCN111445969AReduce inventory management costsAccurate sales forecast resultsMedical data miningCharacter and pattern recognitionDispensaryFeature extraction
The invention discloses a sales prediction method and system capable of elastically adapting to noise. The method comprises the steps: obtaining historical sales data of a to-be-predicted product, andcarrying out preprocessing; carrying out feature extraction and feature selection on the preprocessed historical sales data; carrying out elastic error calculation on the selected features, wherein the elastic error calculation comprises error function and piecewise error calculation of a machine learning model; introducing the elastic error calculation into the machine learning model, and training the machine learning model by using the preprocessed historical sales data; and inputting related data for predicting future sales of the product into the trained machine learning model to generatea prediction result. According to the method, an accurate sales prediction result can be output, and the inventory management cost of enterprise departments such as hospitals and medicinestores can be reduced according to the sales prediction result; and suppliers such as pharmaceutical factories can perform effective production arrangement according to reasonable prediction, so that the purchasing achievement rate is increased.
Owner:中电药明数据科技(成都)有限公司

Shipborne method for preparing organic fertilizer and coproducing antibacterial building material by utilizing sludge

The invention relates to a shipborne method for preparing an organic fertilizer and coproducing an antibacterial building material by using sludge. The method comprises the following steps: exploring,designing and sucking sludge, carrying out primary solid-liquid separation to lower the water content to 80% or below, stirring, carrying out air floatation to separate heavy metals, organic mattersand mud sand, sucking the organic matters from the upper layer of a separation tank, and carrying out fermentation compounding to obtain the organic fertilizer. The silt sediment is dehydrated for thesecond time to enable the water content to reach 20%-50%, the special cementing material is added according to 5%-30% of the silt dry basis, and the building block, the water permeable brick and thebuilding antibacterial building material with the antibacterial function can be obtained through stirring and forming. According to the technical method, land acquisition is not needed, secondary pollution is avoided, the method is environmentally friendly, the developed antibacterial veneer board is particularly suitable for public places of high-risk groups and sterile wards, food factories, pharmaceutical factories and high-end residences of the public places in a wide range, and good news is brought to health of people.
Owner:雷志刚 +1

Block making method of plant medicinal materials and formula medicinal materials

The invention discloses a block making method of plant medicinal materials and formula medicinal materials. The block making method serves as a new method for processing medicinal materials. The block making method is characterized by processing plant medicinal materials and formula medicinal materials into blocks. The block making method adopts the well-known block pressing technology and can process plant medicinal materials, medicinal materials for osteopathic external formulas and medicinal materials for health-care medicated bath formulas into blocks through manual operation or small machines or large machines. Compressed blocks of medicinal materials can keep drug properties stable for a long time, interior microorganism cannot enter the compressed blocks easily, the compressed blocks are unlikely to mildew and rot, quality of medicinal materials is ensured, and like brick tea, the longer the compressed blocks of medicinal materials are stored, the more gentile quality the compressed blocks of medicinal materials have. The block making method has huge economic significance and practical significance in greatly reducing package, storage and transport cost, making it convenient for pharmaceutical factories, hospitals and drugstores to use medicinal materials and making it convenient for doctors to make a prescription and dispense medicines and patients to use medicinal materials. The block making method has wide application prospect in the medicinal materials processing field.
Owner:吴建华 +1

Creatine phosphate sodium oral solid preparation and preparation method thereof

The invention discloses a creatine phosphate sodium oral solid preparation and a preparation method thereof, relating to an oral solid preparation and a preparation method thereof. The invention solves the problem that the existing pharmaceutical factories can not produce the creatine phosphate sodium oral solid preparation at home and abroad. The creatine phosphate sodium oral solid preparation consists of creatine phosphate sodium, starch, carboxymethyl starch sodium, microcrystalline cellulose and absorbefacient. The method comprises the steps of: weighing raw materials, drying and screening, mixing and filling to obtain an enteric capsule. The creatine phosphate sodium oral solid preparation consists of creatine phosphate sodium, absorbefacient, microcrystalline cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose solution, magnesium stearate, acrylic resin II, ethanol, twain-80, castor oil and phthalic acid diethyl ester. The method comprises the steps of: weighing raw materials, screening, preparing wet granule, tabletting, spraying casing liquid to obtain an enteric coated tablet. The invention realizes the preparation of the creatine phosphate sodium oral solid preparation, and can protect cardiac muscle and skeletal muscle.
Owner:哈尔滨博莱制药有限公司

Traditional Chinese medicine ice agent

The invention is named as a traditional Chinese medicine ice agent, belongs to the fields of preparation and application of traditional Chinese medicines, particularly relate to preparation, transportation, storage and application of the traditional Chinese medicine ice agent, and is mainly used for solving the problems that a current traditional Chinese medicine decoction is individual in medicine decoction, troublesome in medicine decoction and inopportune in medication. The traditional Chinese medicine ice agent is prepared in the manner that a preparation link of the traditional Chinese medicine decoction is preset to a pharmaceutical factory, various traditional Chinese medicines are separately extracted in the pharmaceutical factory, a principle that water is solidified to obtain iceat low temperature is used for making a corresponding traditional Chinese medicine ice agent product for clinical use by doctors and patients. During clinical use, the patients can compound various corresponding traditional Chinese medicine ice agent products by a recipe, and after mixing and melting are performed, the traditional Chinese medicine ice agent is immediately used or taken to the home for refrigeration for standby application. The traditional Chinese medicine ice agent which can be used when being taken can solve the problems that the traditional Chinese medicine decoction is individual in medicine decoction, troublesome in medicine decoction and inopportune in medication, clinical characteristics of the traditional Chinese medicine decoction are reserved, the medication according to a clinical recipe by the doctors is not influenced, and the patients can easily accept treatment with traditional Chinese medicines.
Owner:蒲红旭
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