Amino acid zwitter ion hydrogel material and preparation method thereof

A zwitterion and amino acid technology, applied in the field of functional polymer materials, can solve the problems of high price of zwitterion monomers, complicated preparation methods, expensive phosphorylcholine monomers, etc.
CN103435746BInactive Publication Date: 2015-07-15SOUTHEAST UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTHEAST UNIV
Publication Date
2015-07-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an amino acid zwitter ion hydrogel material and a preparation method thereof. The amino acid zwitter ion hydrogel material is a product of an epoxy ring-opening reaction of a crosslinked polymer containing epoxy groups and amino acid, amino-acid ester or polypeptide containing primary amine groups or secondary amine groups, and has characteristics of zwitter ions when the pH value is about 7. The preparation method comprises the step of performing the epoxy ring-opening reaction on the crosslinked polymer containing the epoxy groups and the amino acid, amino-acid ester or polypeptide containing the primary amine groups or secondary amine groups under an alkaline condition that the temperature is 30-150 DEG C and the pH value is 8-14. The amino acid zwitter ion hydrogel material has the characteristics of hydrophilic property and bio-adhesion resistance, and can be used as a contact lens, a wound covering material, a tissue repair material, a drug carrier or water absorbent.
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Description

technical field

[0001] The invention belongs to the technical field of functional polymer materials, and in particular relates to an amino acid zwitterionic hydrogel material, a preparation method and an application thereof. Background technique

[0002] Hydrogels are three-dimensional crosslinked network polymer materials containing a large number of water molecules. Polymethacrylate-β-hydroxyethyl methacrylate is the earliest hydrogel material used in medicine. It is mainly used as a contact lens material and has good mechanical properties, optical properties and biocompatibility. However, this material has a low water content of about 38%, has a certain degree of bioadhesion, and is prone to protein and lipid deposition during wearing.

[0003] Hydrogel materials can also be used as wound covering materials to maintain a certain degree of humidity in the wound, which is beneficial to wound healing. There are many types of hydrogel wound covering products at home and abr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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