Capsule for treating alcoholic cardiomyopathy and preparation method thereof
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A technology for alcoholic cardiomyopathy and capsules, which is used in capsule delivery, cardiovascular system diseases, pharmaceutical formulations, etc., to achieve the effect of long medication cycle, reduced drug types and dosages, and good compliance.
Inactive Publication Date: 2015-06-10
邹建峰
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Abstract
Description
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Problems solved by technology
However, the current clinical treatment is mostly based on the treatment of deficiency syndromes, and those with excess syndromes should be rehabilitated, resulting in twice the result with half the effort.
Method used
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Examples
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Embodiment 1
[0035] Example 1, the weight ratio of raw materials: 20 parts of Selaginella, 10 parts of ragweed, 6 parts of iron rice, 10 parts of Hovenia trifoliata, 6 parts of Sophora flavescens, 10 parts of sage, 10 parts of bobbins, 10 parts of cat's claw 10 parts of mint, 2 parts of gecko, 6 parts of Ganfengchai, 20 parts of Jiaoguya.
[0036]The preparation method of Example 1 is: mix Selaginella chinensis, rag grass, iron rice, Hovenia aurantium, Sophora flavescens, sage, bobbin, cat's claw, mountain mint, gecko, chamomile, burnt grain buds, add water and decoct, Take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide into two parts and take it in the morning and evening.
Embodiment 2
[0037] Example 2, the weight ratio of raw materials: 10 parts of Selaginella, 6 parts of ragwort, 3 parts of iron rice, 6 parts of Hovenia trifoliata, 3 parts of Sophora flavescens, 6 parts of sage, 6 parts of bobbin, 6 parts of cat's claw 6 parts of mint, 1 part of gecko, 3 parts of chai feng chai, 10 parts of burnt grain buds.
Embodiment 3
[0038] Example 3, raw material drug weight ratio: 20 parts of Selaginella, 10 parts of ragweed, 6 parts of iron rice, 10 parts of Hovenia trifoliata, 6 parts of Sophora flavescens, 10 parts of sage, 10 parts of bobbin, 10 parts of cat's claw 10 parts of mint, 2 parts of gecko, 6 parts of Ganfengchai, 20 parts of Jiaoguya.
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Abstract
The invention discloses a capsule for treating alcoholic cardiomyopathy and a preparation method thereof. The capsule is applied to the therapy of alcoholic cardiomyopathy. The preparation method is characterized by comprising the steps of (1) distilling Gastrodia elata Bl., Stachys kouyangensis (Van.) Dunn and Sophora flavescens Ait. by water vapor, so as to extract volatile oil for later use, and enabling dregs to be standby; (2) crushing Gekko gecko Linnaeus and Setaria italica (L.) Beauv. into fine powder for later use; (3) uniformly mixing Selaginella tamariscina (Beauv.) Spring, Begonia handelii Irmsch., Poncirus tuifoliata (L.) Raf., Polygonum aviculare L., Ranunculus ternatus Thunb., Dracocephalum moldavica L., Callicarpa nudiflora Hook. Et Arn. and the dregs obtained in the step (1), carrying out ethanol extraction twice, merging two alcohol extracts, filtrating, recovering ethanol, and carrying out depressurized concentration, so as to form an extract; (4) adding the fine powder obtained in the step (2) into the extract obtained in the step (3), uniformly mixing, drying at the temperature of 60 DEG C, crushing into fine powder, adding polysorbate-80, granulating, drying, finishing, spraying the volatile oil obtained in the step (1), uniformly mixing, and encapsulating, thereby obtaining the capsule. Proved by clinical trials, the capsule has the characteristics of good treatment effect and relatively high safety in the therapy of alcoholic cardiomyopathy, so that the capsule is worthy of clinical application and popularization.
Description
technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a capsule for treating alcoholic cardiomyopathy and a preparation method thereof. Background technique [0002] The onset of alcoholic cardiomyopathy (ACM) is closely related to long-term heavy alcohol intake, and it mostly occurs in men aged 30 to 55, usually with a history of excessive drinking for more than 10 years, with diverse clinical manifestations, the main manifestations Cardiac insufficiency and arrhythmia, including heart enlargement, congestive heart failure, arrhythmia, chest pain, blood pressure changes and other main symptoms. [0003] Alcoholic cardiomyopathy is the result of direct toxicity of ethanol and its metabolite acetaldehyde to the myocardium. The direct toxic effect of alcohol on cardiomyocytes is mainly manifested in the following aspects: ①Ethanol damages the integrity of the myocardial cell membrane, increases the permeability of the cel...
Claims
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Application Information
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