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Medical instrument with slidable coating layer, and syringe

A technology of medical appliances and covering layers, which is applied in the field of medical appliances, can solve the problems of liquid medicine deterioration, difficult prefilling, etc., and achieve the effect of forming good and good sliding properties

Active Publication Date: 2015-04-22
TERUMO KK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, there are also medicines that are filled with the medicine and stored for a long time, and the interaction between the medicine and the lubricant deteriorates the medicine, so it is difficult to prefill.

Method used

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  • Medical instrument with slidable coating layer, and syringe
  • Medical instrument with slidable coating layer, and syringe
  • Medical instrument with slidable coating layer, and syringe

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] (ingredient 1a)

[0104] 43g of 1,5-divinyl-3,3-bis[(vinyldimethylsilyl)oxy]-1,1,5,5-tetramethylpentanetrisiloxane, octamethyl 445 g of cyclotetrasiloxane and 1.5 g of trifluoromethanesulfonic acid were weighed into a 1 L eggplant-shaped flask, and reacted at 80° C. for 6 hours while stirring. The reaction product was returned to room temperature, 1.2 g of calcium carbonate was added and stirred for 3 hours, the calcium carbonate was removed by filtration to complete the polymerization, and the reaction product was removed under reduced pressure (3 kPa) at 150° C. for 2 hours. Polysiloxane with a branched structure is obtained through polymerization. The obtained polysiloxane had a viscosity of 53 mPa·s and a vinyl content of 2.2 wt%. The resulting product was used as component 1a.

[0105] (ingredient 1b)

[0106] Polymethylhydrogensiloxane (100 mol % of hydrogen groups bonded to silicon atoms, viscosity of 30 mPa·s, molecular weight of 2,100) having trimethylsilyl...

Embodiment 2

[0114] (ingredient 1a)

[0115] 22g of 1,5-divinyl-3,3-bis[(vinyldimethylsilyl)oxy]-1,1,5,5-tetramethylpentanetrisiloxane, octamethyl 593 g of cyclotetrasiloxane and 1.5 g of trifluoromethanesulfonic acid were weighed into a 1 L eggplant-shaped flask, and reacted at 80° C. for 6 hours while stirring. The reaction product was returned to room temperature, 1.2 g of calcium carbonate was added and stirred for 3 hours, the calcium carbonate was removed by filtration to complete the polymerization, and the reaction product was removed under reduced pressure (3 kPa) at 150° C. for 2 hours. Polysiloxane with a branched structure is obtained through polymerization. The obtained polysiloxane had a viscosity of 168 mPa·s and a vinyl content of 0.9 wt%. The resulting product was used as component 1a.

[0116] (ingredient 1b)

[0117] Using a methylhydrogensiloxane-dimethylsiloxane copolymer with trimethylsilyl groups at both ends (content of hydrogen groups bonded to silicon atoms: 3...

Embodiment 3

[0125] (ingredient 1a)

[0126] 43g of 1,5-divinyl-3,3-bis[(vinyldimethylsilyl)oxy]-1,1,5,5-tetramethylpentanetrisiloxane, 1,3 , 18g of 5,7-tetravinyltetramethylcyclotetrasiloxane, 445g of octamethylcyclotetrasiloxane, and 1.5g of trifluoromethanesulfonic acid were weighed into a 1L eggplant-shaped flask, and carried out at 80°C under stirring for 6 hour response. The reaction product was returned to room temperature, 1.2 g of calcium carbonate was added and stirred for 3 hours, the calcium carbonate was removed by filtration to complete the polymerization, and the reaction product was removed under reduced pressure (3 kPa) at 150° C. for 2 hours. Polysiloxane with a branched structure is obtained through polymerization. The obtained polysiloxane had a viscosity of 136 mPa·s and a vinyl content of 3.2 wt%. The resulting product was used as component 1a.

[0127] (ingredient 1b)

[0128] Polymethylhydrogensiloxane (100 mol % of hydrogen groups bonded to silicon atoms, visc...

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Abstract

The medical appliance with a sliding covering layer which is in contact with and moves on the inner surface of a medical member or the inner surface of a body cavity of the present invention has a sliding covering layer provided on a part in contact with a medical member or a body cavity, and the sliding covering layer Consists of a composition containing a solvent-free curable silicone-based resin.

Description

technical field [0001] The present invention relates to a medical device having a slidable film having stable slidability, and relates to, for example, a spacer for a syringe and a syringe in which the spacer of the syringe has stable slidability. Background technique [0002] Conventionally, prefilled syringes prefilled with medical solutions have been used for reasons such as taking wrong medicines, preventing nosocomial infections, disposability, and efficiency of hospital work. No matter what kind of syringe is used for the prefilled syringe, the syringe is generally composed of an outer cylinder, a spacer slidable in the syringe, and a plunger that operates the spacer to move. In most syringes, in order to improve the slidability of the gasket and obtain high flow accuracy without serious spraying when the liquid is sprayed out, silicone oil or the like is coated on the sliding part of the outer surface of the gasket or the syringe as a lubricant. on the inner surface ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L29/00A61L31/00A61M5/315F16J15/32
CPCA61M5/31513F16J15/3284A61M2205/0222A61M2005/3104A61M2025/0046A61M2025/09133A61L29/14A61L29/085C08L83/04
Inventor 阿部吉彦渡边英二
Owner TERUMO KK
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