Drug for preventing and treating pigeon paramyxovirus type I (PPMV-I) and preparation method thereof

A virus disease, type I technology, applied in the field of medicine and its preparation for the prevention and treatment of pigeon type I paramyxovirus disease, can solve the problem of no specific treatment medicine, achieve the effect of improving the taste of medicine, easy operation and improving effect

Active Publication Date: 2014-03-26

合浦和润农业有限公司

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AI-Extracted Technical Summary

Problems solved by technology

At present, there is still no specific treatment drug, and there is no formal inactivated vaccine for pigeo...

Method used

The medicine that the present embodiment is obtained is mixed in the feed of pigeon, selects 100 sick pigeons at random, by every sick pigeon 20g amount, 2 days is a course for the treatment of, after 2 days of this medicine treatment, sick pigeon enteritis, The symptoms of diarrhea were obviously alleviated, the neurological symptoms were relieved, and the right amount obviously increased. On the 6th day after the medication, 95 of the treated pigeons were cured, 5 died, and the cure rat...

Abstract

The invention discloses a drug for preventing and treating pigeon paramyxovirus type I (PPMV-I). The drug is mainly prepared from the following raw materials in parts by weight: 20-40 parts of honeysuckle, 40-60 parts of scullcap, 50-70 parts of goldthread, 50-80 parts of weeping forsythia, 40-60 parts of dyer woad leaves, 30-50 parts of felwort, 45-60 parts of common andrographis herb, 32-43 parts of wild chrysanthemum flower, 35-52 parts of poria with hostwood, 34-50 parts of agaric, 30-45 parts of liquorice, 10-20 parts of realgar, 5-10 parts of dried ginger, 5-10 parts of herba schizonepetae, 1-5 parts of kudzuvine root, 1-5 parts of akebia stem, 40-50 parts of wheat, 20-30 parts of carthamus fruit, 40-50 parts of sorghum, 4-10 parts of enrofloxacin, 2-5 parts of neomycin, 30-50 parts of vitamin, 13-26 parts of glucose and 20-30 parts of kidney swollen antidote. The drug is prepared through the steps of material selection, mixing, pelleting and drying. According to the invention, drug particles are prepared by mixing traditional Chinese medicines and western medicines; the drug is a result summarized and explored from practices in breeding pigeons for a long time; the drug has a good effect in preventing and treating PPMV-I and is worthy of popularization and application.

Application Domain

Organic active ingredientsInorganic active ingredients +3

Technology Topic

HoneysuckleAkebia Stem +24

Examples

Experimental program(3)

Example Embodiment

[0018] Example 1

[0019] A medicine for preventing and treating type I paramyxovirus disease of pigeons, which is mainly composed of the following raw materials by weight: honeysuckle 35g, Huangling 20g, Coptis chinensis 35g, Forsythia 40g, Daqingye 45g, Gentiana 40g, Andrographis paniculata 50g, Wild Chrysanthemum 35g, Fushen 45g, Polyporus 43g, Licorice 38g, Realgar 10g, Dried Ginger 6g, Nepeta 8g, Pueraria Root 3g, Mutong 3g, Wheat 40g, Baihuazi 25g, Sorghum 45g, Enrofloxacin 5g , 4g of neomycin, 40g of vitamins, 20g of glucose and 25g of antidote for nephrosis.

[0020] Prepared by the following methods:

[0021] 1) Material selection: honeysuckle, Huangling, Coptidis, Forsythia, Daqingye, Gentiancao, Andrographis, Wild Chrysanthemum, Poria, Polyporus, Licorice, Realgar, Ginger, Nepeta, Pueraria, Mutong, Wheat, Baihuazi and sorghum were screened, removed impurities, washed and dried, and then pulverized into 100-mesh fine powder using a pulverizer for use;

[0022] 2) Mixing: the various raw material fine powders obtained in step 1) are mixed by weight to obtain a premix, and then enrofloxacin, neomycin, vitamins, glucose, and nephropathy antidote are mixed with premix according to weight. The mixture is mixed evenly;

[0023] 3) Granulation: put the mixture obtained in step 2) into a granulator, set the pressure to 1Mpa, and granulate at a rotational speed of 30 rpm to obtain a finished product with a particle size of 2mm.

[0024] 4) Drying: put the finished product in a dryer for drying, the temperature of the dryer is set to 100 ° C, and dry for 30 minutes, so that the moisture content of the finished product is less than 5%.

[0025] The medicine obtained in this example was mixed in the feed of pigeons, and 100 sick pigeons were randomly selected, and 2 days were a course of treatment by the amount of 20 g of each sick pigeon. Relief, the neurological symptoms are relieved, and the appropriate amount is significantly increased. On the 6th day after the treatment, 95 pigeons were cured and 5 died, and the cure rate was 95%.

Example Embodiment

[0026] Example 2

[0027] A medicine for preventing and treating type I paramyxovirus disease of pigeons, which is mainly composed of the following raw materials by weight: honeysuckle 35g, Huangling 20g, Coptis chinensis 35g, Forsythia 40g, Daqingye 45g, Gentiana 40g, Andrographis paniculata 50g, Wild Chrysanthemum 35g, Fushen 45g, Polyporus 43g, Licorice 38g, Dried Ginger 6g, Nepeta 8g, Pueraria Root 3g, Wheat 40g, Baihuazi 25g, Sorghum 45g, Enrofloxacin 5g, Neomycin 4g, Vitamins 40g, glucose 20g and nephropathy antidote 25g.

[0028] Prepared by the following methods:

[0029] 1) Material selection: honeysuckle, Huangling, Coptidis, Forsythia, Daqingye, Gentiancao, Andrographis, Wild Chrysanthemum, Poria, Polyporus, Licorice, Realgar, Ginger, Nepeta, Pueraria, Mutong, Wheat, Baihuazi, sorghum, enrofloxacin, neomycin, vitamin, glucose and nephropathy antidote were screened, removed impurities, washed and dried, and then pulverized into 150-mesh fine powder with a pulverizer for use;

[0030] 2) Mixing: the various raw material fine powders obtained in step 1) are mixed by weight to obtain a premix, and then enrofloxacin, neomycin, vitamins, glucose, and nephropathy antidote are mixed with premix according to weight. The mixture is mixed evenly;

[0031] 3) Granulation: put the mixture obtained in step 2) into a granulator, set the pressure to 1.5Mpa, and granulate at a rotational speed of 50 rpm to obtain a finished product with a particle size of 3mm.

[0032] 4) Drying: put the finished product in a dryer for drying, the temperature of the dryer is set to 120°C, and dry for 20 minutes, so that the moisture content of the finished product is less than 5%.

[0033] The medicine obtained in this example was mixed in the feed of pigeons, and 100 sick pigeons were randomly selected, and 2 days were a course of treatment by the amount of 25 g of each sick pigeon. Relief, the neurological symptoms are relieved, and the appropriate amount is significantly increased. On the 6th day after the treatment, 93 pigeons were cured and 7 died. The cure rate is 93%.

Example Embodiment

[0034] Example 3

[0035] A medicine for preventing and treating type I paramyxovirus disease of pigeons, which is mainly composed of the following raw materials by weight: honeysuckle 40g, Coptis chinensis 70g, Forsythia 80g, Daqingye 60g, Gentiana 50g, Andrographis paniculata 60g, wild chrysanthemum 43g, Licorice 45g, Realgar 20g, Nepeta 10g, Mutong 5g, Wheat 50g, Baihuazi 30g, Sorghum 50g, Enrofloxacin 10g, Neomycin 5g, Vitamin 50g, Glucose 26g, and Nephropathy Antidote 30g.

[0036] Prepared by the following methods:

[0037] 1) Material selection: Honeysuckle, Coptis, Forsythia, Daqingye, Gentian, Andrographis, Wild Chrysanthemum, Licorice, Realgar, Nepeta, Mutong, Wheat, Baihuazi, Sorghum, Enrofloxacin, New Mold Supplements, vitamins, glucose and antidote for nephrosis were screened, removed impurities, washed and dried, and then pulverized into 200-mesh fine powder by a pulverizer for use;

[0038] 2) Mixing: the various raw material fine powders obtained in step 1) are mixed by weight to obtain a premix, and then enrofloxacin, neomycin, vitamins, glucose, and nephropathy antidote are mixed with premix according to weight. The mixture is mixed evenly;

[0039] 3) Granulation: put the mixture obtained in step 2) into a granulator, set the pressure to 2Mpa, and granulate at a rotational speed of 80 rpm to obtain a finished product with a particle size of 4mm.

[0040] 4) Drying: put the finished product in a dryer for drying, the temperature of the dryer is set to 150°C, and dry for 10 minutes, so that the moisture content of the finished product is less than 5%.

[0041] The medicine obtained by the present embodiment was mixed in the feed of pigeons, and 100 sick pigeons were randomly selected. According to the 15g amount of each sick pigeon, 2 days were a course of treatment. After 2 days of treatment with this medicine, the symptoms of enteritis and diarrhea of sick pigeons were obvious. Relief, the neurological symptoms are relieved, and the appropriate amount is significantly increased. On the 6th day after the treatment, 90 pigeons were cured and 10 died. The cure rate is 90%.

PUM

Property	Measurement	Unit
Particle size	2.0 ~ 4.0	mm
Particle size	2.0	mm
Particle size	3.0	mm

Description & Claims & Application Information

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Classification and recommendation of technical efficacy words

Improve drug taste
Improve the effect

Molnupiravir taste-masking particles and preparation method thereof

PendingCN114306284AGuaranteed stabilityImprove drug taste

Owner:ZENJI RES LAB

Drug for preventing and treating pigeon paramyxovirus type I (PPMV-I) and preparation method thereof

AI-Extracted Technical Summary

Problems solved by technology

Method used

Abstract

Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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