Sample introduction device for improving detection sensitivity of ion mobility spectrometry (IMS)

A technology of detection sensitivity and ion mobility spectrometry, which is applied in the field of thermal analysis sampling device, can solve the problems of difficult quantitative detection, unstable sample gas flow, overheating decomposition, etc., to improve detection sensitivity, improve sample injection efficiency, and fast temperature rise Effect

Inactive Publication Date: 2014-03-26
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
View PDF5 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A heating plate or heating tube is installed in front of the injection port to vaporize the sample. Usually, the volume of these injection devices is large, the sample analysis time is long, and the concentration of the sample is low. During the injection process, the sample is prone to local temperature unevenness. Losses due to instability of the sample flow, etc.
Diffic

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Sample introduction device for improving detection sensitivity of ion mobility spectrometry (IMS)
  • Sample introduction device for improving detection sensitivity of ion mobility spectrometry (IMS)
  • Sample introduction device for improving detection sensitivity of ion mobility spectrometry (IMS)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] figure 1 Schematic diagram of the device for the ion mobility spectrometry thermal desorption sampler designed in the invention, in which (1) injection septum, (2) purge gas outlet, (3) septum purge chamber, (4) total gas flow Inlet, (5) Connecting nut, (6) Thermal desorption chamber, (7) Thermal desorption chamber heating module, (8) Connecting pipe connecting the sample injector to the ion mobility tube of the ion mobility spectrometer, (9) Temperature sensor , (10) heating rod, (11) insulating cotton layer, (12) wrapping the outer packaging shell of the sampler.

[0032] Accurately measure 1-50μL, 1ppt-100ppm different sample solutions with a micro-sampling needle. The sample to be tested is sampled through a manual injection needle with an injection volume of 1-20 μL, and the needle is directly inserted into the liner through the central concave hole of the injection septum (1). The sample injected into the liner is instantly vaporized at the set higher temperature....

Embodiment 2

[0035] figure 2 In the positive ion mode, this sampler is used to detect the ion mobility spectrum of 1pg dibutyl phthalate; use a micro-syringe to accurately measure 1μL of dibutyl phthalate solution with a concentration of 1ppb, that is, 1pg sample. In the positive ion mode, the ion mobility spectrometer was used as the detection instrument, and the sample was injected manually. In the positive ion mode, the air reagent ion peak (RIP) appears at about 4.08ms. The peak migration time of dibutyl phthalate is about 7.36ms. The signal is so strong that it nearly masks the air reagent ion peak.

[0036] Compared with the solenoid valve injector designed and developed before, 1pg is almost the detection limit of those instruments. It can be seen that this specially designed thermal desorption sampler is very sensitive for testing dibutyl phthalate.

[0037] In the same way, image 3 In the positive ion mode, this sampler is used to detect the ion mobility spectrum of 1fg di...

Embodiment 3

[0040] Figure 4 It is ion mobility spectrometry in negative ion mode, and the ion mobility spectrogram of 1ng TNT detected by a solenoid valve injector; accurately measure 1 μL of TNT solution with a concentration of 1ppm with a micro-syringe needle, that is, 1ng sample. In the negative ion mode, the ion mobility spectrometer was used as the detection instrument, and the sample was injected manually. In the negative ion mode, the air reagent ion peak (RIP) appears at about 6.12ms, and the signal strength is 400mv. The peak migration time of TNT is 9.02ms, and the signal strength is about 180mv. The TNT signal was weaker than the RIP signal, and the ratio of the two signals was 0.45.

[0041] Figure 5 Ion mobility spectrometry in negative ion mode, the thermal desorption sampler designed in the invention detects the ion mobility spectrogram of 1ngTNT; accurately measure 1μL of TNT solution with a concentration of 1ppm with a micro-injection needle, that is, 1ng sample. In...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Resistanceaaaaaaaaaa
Login to view more

Abstract

The invention relates to a sample introduction device for improving detection sensitivity of ion mobility spectrometry (IMS) by improving the sample introduction efficiency of the IMS. The device comprises a sample introduction pad, a purging cavity inside the pad, a liner-containing thermal desorption chamber, an connector for the thermal desorption chamber and an ion mobility pipe, a heating rod, a temperature sensor and an external thermal insulation component. The IMS can be directly used for detection for gas phase, liquid phase or solid phase samples. The sample introduction efficiency of the sample is improved, and the sensitivity of the detected sample is improved. Compared with a traditional solenoid valve or a stepping motor sample injector, the sample introduction device has the advantages that the detection sensitivity of the IMS is greatly improved. Compared with a negative ion mode, the sensitivity for testing the TNT sample is 100 times higher, phthalic acid ester is tested in a positive ion mode, and the sensitivity for testing the dibutyl phthalate is 1000 times higher. With the designs of strict sealing structure, carrier gas preheating and the like, the detection repeatability of the tested sample is high, and qualitative and quantitative analysis test of the IMS is promoted.

Description

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2023 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap