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Plant capsule composition of seaweed colloid and preparation method thereof

A plant capsule and composition technology, which is applied in the direction of capsule delivery, medical preparations of non-active ingredients, pharmaceutical formulas, etc., can solve the problems of high cost of capsules, avoid the risk of disease, low moisture content, and avoid microorganisms pollution effect

Active Publication Date: 2014-05-07
漳州市新明生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The high cost of capsules due to the use of gellan gum is the main problem of this invention

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Preparation of Vegetable Capsules of Seaweed Colloid.

[0039] Sol—>Heating—>Plant Cellulose—>Dipping Glue to Make Embryo—>Drying—>Hulling—>Product.

[0040] Sol: Weigh 20.3g of λ-type carrageenan, add 49g of water, add 8.1g of glycerin, stir continuously to make it fully absorb water and swell and dissolve, let stand at room temperature for 8 hours to remove foam, and make the glue clear.

[0041] Heating: Heat the clarified liquid to 80°C, add 89g of hydroxypropyl cellulose and 2g of starch, and keep stirring to fully dissolve the plant cellulose and starch.

[0042] Glue dipping to make embryos: use a capsule mold, dip the mold rod into the glue solution to make capsule embryos. First select the mold rod of 3# specification and fix it on the template, and lubricate it with an appropriate amount of lubricant. Dip the upper end of the mold rod downwards into the glue solution, wait for the glue liquid to fully submerge the mold rod for 6 seconds, then slowly lift the...

Embodiment 2

[0046] Preparation of Vegetable Capsules of Seaweed Colloid.

[0047] Sol—>Heating—>Plant Cellulose—>Dipping Glue to Make Embryo—>Drying—>Hulling—>Product.

[0048] Sol: Weigh 15kg of mixed carrageenan, the ratio of λ type to κ type is 1:1, add 61kg of water, add 8.1kg of ethanol, stir continuously to make it fully absorb water and swell and dissolve, let stand at room temperature for 8 hours to remove foam, and make the glue clarify.

[0049] Heating: Heat the clarified liquid to 86°C, add 92kg of hypromellose and 1.5kg of starch, and keep stirring to fully dissolve the plant cellulose and starch.

[0050] Glue dipping to make embryos: use a capsule mold, dip the mold rod into the glue solution to make capsule embryos. First select the mold rod of 3# specification and fix it on the template, and lubricate it with an appropriate amount of lubricant. Dip the upper end of the mold rod downward into the glue solution, wait for the glue liquid to fully submerge the mold rod for...

Embodiment 3

[0054] Effects of the fraction of algal colloids on the viscosity and film-forming properties of sol liquids.

[0055] (1) Using the same technological process as in Example 1, weigh seaweed colloid and hydroxypropyl cellulose in different proportions, and prepare capsules respectively.

[0056] (2) Measure the viscosity with a precision digital viscometer.

[0057] (3) Measure its thickness with a precision thickness gauge.

[0058] Table 1 The effect of the number of seaweed colloids on the viscosity and film-forming properties of sol

[0059] Numbering Seaweed colloid (g) Vegetable cellulose (g) Viscosity (mPs·s) Film formation Thickness (0.01mm) 1 5.0 89 2370.2 Difficult to shape, thin 5.4±0.5 2 10.0 89 2300.4 Good film formation 8.3±0.4 3 15.0 89 2261.0 Good film formation 9.1±0.3 4 20.3 89 2330.7 Good film formation 9.5±0.5 5 22.0 89 2439.0 Good film formation 10.4±0.6 6 25.0 89 2309.3 Thick ...

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PUM

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Abstract

The invention discloses a plant capsule composition of seaweed colloid and a preparation method thereof. The composition comprises the following components in parts by weight: 1-30 parts of lambda carrageenan, 50-120 parts of plant cellulose, 1-15 parts of alcohols, 0.5-10 parts of starch, and 30-90 parts of water. The plant capsule can be used as auxiliary materials of medicines and functional foods, and the raw materials are from plants and safe to use, so that potential pathogenic risks of animal source materials can be avoided; the plant capsule composition is good in stability, does not deform in high-temperature high-humidity environment, and is not fragile in a cold and dry environment; the plant capsule is wider in application range, and is suitable for Muslim, Judaism areas and vegetarians.

Description

technical field [0001] The invention relates to a plant capsule as an auxiliary material for medicine and functional food, more specifically, the invention relates to a plant capsule composition containing λ-type carrageenan and a preparation method thereof. Background technique [0002] Capsules are one of the most commonly used pharmaceutical filling materials for modern pharmaceuticals and functional foods. With their unique advantages, they play an indispensable role in the production and manufacture of pharmaceuticals and functional foods. Capsules have the following characteristics: smooth and beautiful appearance, which can cover up the inappropriate bitterness and odor of raw materials, making it easy for consumers to accept; high bioavailability of functional factors, small amount of excipients, rapid disintegration in the gastrointestinal tract, and general administration. After 3-10 minutes, it can disintegrate and release functional substances; compared with pill...

Claims

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Application Information

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IPC IPC(8): A61K47/38A61K47/36A61K9/48
Inventor 不公告发明人
Owner 漳州市新明生物科技有限公司
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