Antrodia cinnamomea effervescent tablet and preparation method thereof
A technology of effervescent tablets and Antrodia cintrodia, which is applied in medical formulas, medical preparations of non-active ingredients, drug delivery, etc., can solve problems such as restrictions on the utilization of Antrodia cinnamomea, low utilization rate of active ingredients in Antrodia cintrodia, inconvenient taking and carrying, etc., to achieve Increase solubility, safe and convenient food, and enhance stability
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Example Embodiment
[0016] The embodiment of the present invention also provides a preparation method of Antrodia cinnamomea effervescent tablets, which includes the following steps:
[0017] Mix the Antrodia cinnamomea extract, filler, and sweetener evenly to make a mixture;
[0018] Mixing the mixture with an alkali source and a lubricant to prepare alkali particles;
[0019] Mixing the mixture with an acid source and a lubricant to prepare acid particles;
[0020] The acidic granules and the basic granules are compressed into tablets to obtain the Antrodia camphorata effervescent tablets.
[0021] Specifically, the Antrodia cinnamomea extract includes an Antrodia cinnamomea water extract and / or an alcohol extract of Antrodia cinnamomea encapsulated with cyclodextrin. Among them, the preparation method of the Antrodia cinnamomea water extract is: take the Antrodia cinnamomea raw materials and water in a weight ratio of 1: (5-15), extract at 80-95°C for 30-60 minutes, filter, and take the filtrate; repea...
Example Embodiment
[0027] Example 1
[0028] Take the Antrodia cinnamomea fruiting bodies obtained by the basswood culture method, wash and chop them. Add Antrodia cinnamomea raw materials and water in a volume ratio of 1:10, extract at 80°C for 60 minutes, filter, and take the filtrate; repeat twice; combine the filtrate obtained three times to obtain an Antrodia cinnamomea water extract. Concentrate in a vacuum at 80°C into a paste, then use microwave vacuum drying, pulverize, and pass through an 80-mesh sieve to obtain a powdered Antrodia camphorata water extract.
[0029] Add 8 times the weight of the Antrodia camphorata raw material to the above-mentioned Antrodia camphorata raw material, reflux at 90°C for 1 hour, filter, and take the filtrate; repeat three times and combine the obtained filtrate three times to obtain the Antrodia camphorata ethanol extract. According to the volume ratio of β-cyclodextrin:purified water=1:20, add β-cyclodextrin and pure water to mix, where the weight of β-cycl...
Example Embodiment
[0032] Example 2
[0033] An Antrodia cinnamomea mycelium obtained by a liquid submerged fermentation method is taken, washed and crushed. Add Antrodia cinnamomea raw materials and water in a volume ratio of 1:10, extract at 80°C for 60 minutes, filter, and take the filtrate; repeat twice; combine the filtrate obtained three times to obtain an Antrodia cinnamomea water extract. Concentrate in a vacuum at 80°C into a paste, then use microwave vacuum drying, pulverize, and pass through an 80-mesh sieve to obtain a powdered Antrodia camphorata water extract.
[0034] Add 8 times the weight of the Antrodia camphorata raw material to the above-mentioned Antrodia camphorata raw material, reflux at 90°C for 1 hour, filter, and take the filtrate; repeat three times and combine the obtained filtrate three times to obtain the Antrodia camphorata ethanol extract. According to the volume ratio of β-cyclodextrin:purified water=1:20, add β-cyclodextrin and pure water to mix, where the weight of...
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