Composition for reducing blood sugar and application thereof
A composition and blood sugar technology, which are applied in the directions of drug combinations, plant raw materials, medical preparations containing active ingredients, etc., to achieve the effects of less side effects, convenient use and simple production process
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Embodiment 1
[0025] Embodiment 1, preparation is used for the composition of lowering blood sugar
[0026] The composition (parts by weight) prepared by this embodiment is as follows:
[0027]
[0028] The preparation method of this embodiment composition is as follows:
[0029] 1. Prepare the cinnamon extract:
[0030] Take the original medicinal material of cinnamon, extract twice with 8 times the weight of water, each time for 2 hours, combine the two water extracts; at 60°C, -0.08MPa, concentrate the water extract to a relative density of 1.1 (60°C) , to obtain a concentrated solution; dry the concentrated solution under reduced pressure (-0.09MPa) to obtain a dry extract; crush the dry extract, and pass through an 80-mesh sieve to obtain a fine powder of the extract, which is the cinnamon extract.
[0031] 2. Preparation of American ginseng extract:
[0032] Take the original medicinal material of American ginseng, extract 2 times with 8 times the weight of water, each time for ...
Embodiment 2
[0056] Embodiment 2, the animal experiment of the hypoglycemic function of the product of the present invention
[0057] 1. Materials and methods
[0058] 1.1 Sample: Composition Capsule C prepared in the above examples.
[0059] 1.2 Experimental animals: 120 24-28g female SPF Kunming mice, provided by the Institute of Hygiene and Environmental Medicine, Academy of Military Medical Sciences of the Chinese People's Liberation Army, the certificate number is SCXK (Army) 2009-0030000686.
[0060] 1.3 Experimental animal room: SPF level experimental animal room. Temperature 20-25℃, relative humidity 40-70%RH, certificate number: SYXK (Jin) 2008-0004. The feed is supplied by Beijing Huafukang Biotechnology Co., Ltd., the feed certificate number: SCXK-(Beijing) 2009-0008.
[0061] 1.4 Dosage selection: The intended human dose is 3.6g / day, that is, 3.6g / 60kgBW, which is equivalent to 0.06g / kgBW. This experiment designed a control group and three groups of low, medium and high dose...
Embodiment 3
[0102] Embodiment 3, the hypoglycemic function human body test of the product of the present invention
[0103] 1. Objects and Methods
[0104] 1.1 Test sample: the composition capsule C prepared in the above examples.
[0105] 1.2 Subject Selection
[0106] 1.2.1 Subjects In this study, non-hospitalized diabetic patients with abnormal fasting blood glucose and 2-hour postprandial blood glucose were collected in the Third Central Hospital of Tianjin. After passing the physical examination and informed consent, 100 volunteers were screened for statistics.
[0107] 1.2.2 Inclusion criteria
[0108] Select adult patients with type 2 diabetes whose condition is relatively stable after diet control or oral hypoglycemic drug treatment, and who do not need to change the type and dose of drugs and only take maintenance doses: fasting blood glucose (FBG) ≥ 7.8mm01 / L or postprandial 2h blood glucose (P2hBG ) ≥ 11.1mmol / L; 7.8mmol / L ≥ FBG ≥ 6.7mmol / L (120mg / d1) or 11.1mm01 / L ≥ P2hBG ≥...
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