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Traditional Chinese medicine micropowder for treating swine streptococcosis and preparation method thereof

A technology of Streptococcus suis and micropowder, which can be used in pharmaceutical formulations, antibacterial drugs, non-central analgesics, etc., can solve problems such as multi-drug resistant strains, achieve simple preparation method, convenient use, and solve drug residues and pathogenic bacteria resistance. Effects of medication problems

Inactive Publication Date: 2014-06-04
ANHUI AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the wide application of antibacterial drugs and improper use of antibiotics, under the pressure of drug selection, Streptococcus suis has developed serious drug resistance to antibacterial drugs, and even multi-drug resistant strains have appeared. Anti-inflammation, heat-clearing and detoxification may be a more effective way to treat Streptococcus suis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] 1. Formula ingredients

[0017] By weight, 4 parts of Bupleurum bupleuri, 5 parts of comfrey, 4 parts of Andrographis paniculata, 3 parts of honeysuckle, 3 parts of coptis, 4 parts of pomegranate peel and 3 parts of licorice.

[0018] 2. Preparation method

[0019] (1) Preliminary crushing: weigh the medicinal materials according to the above formula ratio, crush each medicinal material into coarse powder, and mix;

[0020] (2) Superfine pulverization: Utilize a superfine pulverizer to further pulverize the mixed coarse powder in step (1) into a fine powder with a fineness of 500 meshes, that is, to obtain a medicine for treating streptococcus suis of the present invention. Micropowder of traditional Chinese medicine.

[0021] 3. Clinical verification

[0022] Select the clinical manifestations of heating, arthritis, lameness, endocarditis, 41 sick pigs suffering from streptococcus suis disease with decreased appetite, the Chinese medicine micropowder prepared above ...

Embodiment 2

[0024] 1. Formula ingredients

[0025] By weight, 5 parts of bupleurum, 6 parts of comfrey, 4 parts of andrographis paniculata, 4 parts of honeysuckle, 3 parts of berberine, 5 parts of pomegranate peel and 3 parts of licorice.

[0026] 2. Preparation method

[0027] (1) Preliminary crushing: weigh the medicinal materials according to the above formula ratio, crush each medicinal material into coarse powder, and mix;

[0028] (2) Superfine pulverization: Utilize a superfine pulverizer to further pulverize the mixed coarse powder in step (1) into a fine powder with a fineness of 500 meshes, that is, to obtain another method for treating streptococcus suis of the present invention. traditional Chinese medicine micropowder.

[0029] 3. Clinical verification

[0030] Select the clinical manifestations of heating, arthritis, lameness, endocarditis, 51 sick pigs suffering from streptococcus suis disease with decreased appetite, the Chinese medicine micropowder prepared above is mi...

Embodiment 3

[0032] 1. Formula ingredients

[0033] By weight, take 7 parts of Bupleurum bupleurum, 10 parts of comfrey, 8 parts of Andrographis paniculata, 6 parts of honeysuckle, 7 parts of coptis, 7 parts of pomegranate peel and 6 parts of licorice.

[0034] 2. Preparation method

[0035] (1) Preliminary crushing: weigh the medicinal materials according to the above formula ratio, crush each medicinal material into coarse powder, and mix;

[0036] (2) Superfine pulverization: Utilize a superfine pulverizer to further pulverize the mixed coarse powder in step (1) into a fine powder with a fineness of 500 meshes, that is, to obtain another method for treating streptococcus suis of the present invention. traditional Chinese medicine micropowder.

[0037] 3. Clinical verification

[0038] Select the clinical manifestations of heating, arthritis, lameness, endocarditis, 43 sick pigs suffering from streptococcus suis disease with decreased appetite, the Chinese medicine micropowder prepare...

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Abstract

The invention discloses traditional Chinese medicine micropowder for treating swine streptococcosis and a preparation method thereof. The formula of the traditional Chinese medicine micropowder comprises the following components: 4 to 7 parts of radix bupleuri, 5 to 10 parts of lithospermum, 4 to 8 parts of common andrographis herb, 3 to 6 parts of honeysuckle, 3 to 7 parts of coptis chinensis, 4 to 7 parts of pomegranate peel and 3 to 6 parts of licorice root. The traditional Chinese medicine micropowder is prepared into superfine powder through a superfine grinding technology, so that the components in the medicinal materials are easily absorbed. Thus, the superfine powder can effectively perform antibacterial, antiphlogistic, antipyretic and analgesic functions, and can promote the immunity of a swine so as to rapidly recover the body functions. Therefore, the cure rate of the swine streptococcosis can reach more than 90%; and the problems of the medicine residue and the medicine resistance of pathogenic bacteria in meat products are solved. The traditional Chinese medicine micropowder is an oral preparation which can be directly taken in a mixing and feeding manner, thereby being convenient to use. In addition, the traditional Chinese medicine micropowder is simple in preparation method and low in cost, thereby being suitable for industrialized mass production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine micropowder for treating Streptococcus suis and a preparation method thereof. Background technique [0002] Streptococcus suis is a zoonotic infectious disease caused by a variety of hemolytic streptococci, which is prevalent worldwide. Streptococcus suis is one of the important pathogenic bacteria of pigs, which can cause various diseases of pigs and attack pigs of all ages. It is usually characterized by sepsis, meningitis, arthritis, and lymphadenitis. It can also cause meningitis, sepsis, etc. in humans, leading to serious illness and even death. In recent years, streptococcal suis has been widely prevalent in my country, and the morbidity and mortality are high, causing great economic losses to the pig industry. [0003] The antigenic structure of Streptococcus suis is relatively complex. According to the capsular polysaccharide a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/14A61P31/04A61P29/00A61P37/04
Inventor 韩春杨刘翠艳张运海
Owner ANHUI AGRICULTURAL UNIVERSITY
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