The preparation method of acetyl-L-carnitine hydrochloride

A technology of hydrochloride and acetyl, which is applied in the field of pharmaceutical synthesis, can solve the problems such as the side reaction of glacial acetic acid-containing waste liquid in the heating time of materials, and achieve the effects of simple post-processing, good product quality and high yield.
CN103896791BActive Publication Date: 2016-12-28GUANGDONG LONGFU MEDICINE CO LTD
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
GUANGDONG LONGFU MEDICINE CO LTD
Publication Date
2016-12-28

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The present invention relates to a method for preparing (R)-acetyl carnitine hydrochloride by adopting L-carnitine hydrochloride as a raw material. According to the present invention, the problem that the high reaction temperature and the distillation operation process make the material heating time too long so as to cause side effects and produce a large amount of the glacial acetic acid-containing waste liquid in the existing process is solved, the product quality is good, and the yield is high.
Need to check novelty before this filing date? Find Prior Art

Description

(1) Technical field

[0001] The invention belongs to the field of drug synthesis (2) Technical background

[0002] Acetyl L-carnitine hydrochloride, the English name is (R)-Acetyl carnitine hydrochloride, its structural formula is:

[0003]

[0004] Acetyl-levocarnitine is an endogenous substrate for the synthesis of acetylcholine in the human brain, and has neuroprotective and mitochondrial protective effects. It can actively participate in the energy metabolism of mitochondria in cells and correct the DNA transcription of mitochondria. Acetyl-L-carnitine thus prevents the aging and degenerative processes of the nervous system. Because it can stimulate nerve cells to produce protein core cell membranes and release the nerve mediator - acetylcholine, it has the effect of promoting memory improvement and improving recognition ability. Its clinical application is mostly in the form of hydrochloride, namely: acetyl L-carnitine Tine hydrochloride.

[0005] According to rep...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More