Bent optical fiber ATR (attenuated total reflectance) glucose sensor reinforced on basis of silver nanoparticles

Abstract

The invention discloses a bent optical fiber ATR (attenuated total reflectance) glucose sensor reinforced on the basis of silver nanoparticles. The bent optical fiber ATR glucose sensor comprises an optical fiber. The optical fiber comprises an optical fiber core and optical fiber cladding, the optical fiber cladding wraps the outer periphery of the optical fiber core, optical fiber connectors which are used for being connected with external components are respectively connected to two ends of the optical fiber, a bent sensitive area is formed in the middle of the optical fiber, and the silver nanoparticles grow on the outer surface of the portion, which is positioned in the sensitive area, of the optical fiber. The optical fiber is a multi-mode optical fiber. The optical fiber core and the optical fiber cladding are made of silver halide materials, and light with the wavelength ranging from 4 micrometers to 18 micrometers can be transmitted through the optical fiber core and the optical fiber cladding. The portion, which is positioned in the sensitive area, of the optical fiber is of a U-shaped structure or a single-ring structure or a structure with two or more rings. The diameter of each silver nanoparticle ranges from 20 nanometers to 100 nanometers. The bent optical fiber ATR glucose sensor has the advantages that the bent optical fiber ATR glucose sensor is simple in structure and operation, small in size, easy to process and low in cost, and can be subcutaneously implanted into a human body, so that the blood glucose concentration of the human body can be continuously monitored in an online manner and can be directly measured in vivo, and the requirement on continuously monitoring the blood glucose concentration of the human body in real time can be met.

Description

technical field [0001] The present invention relates to a glucose sensor. In particular, it relates to a curved fiber-optic ATR glucose sensor based on silver nanoparticle enhancement. Background technique [0002] Diabetes is a chronic disease that seriously endangers human health, second only to tumors and cardiovascular and cerebrovascular diseases. The traditional method of using biochemical analysis to detect diabetes is traumatic, the measurement speed is slow, improper handling of reagents and related consumables may cause pollution, and continuous measurement cannot be achieved. Minimally invasive blood glucose concentration detection technology is a continuous blood glucose detection technology for measuring glucose concentration in interstitial fluid, which has the characteristics of painless, more realizable and fast measurement speed. Among the current minimally invasive blood glucose detection technologies, the most widely used clinically is the enzyme electro...

AI Technical Summary

Problems solved by technology

Optical fiber is not resistant to high temperature, it is easy to melt if the temperature is too high

Moreover, the above two methods have complex equipment, are not easy to operate continuously, and are expensive

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