Biosensor test strip

Abstract

A biosensor test strip includes: a first working electrode and a second working electrode formed on a base plate, having the second working electrode circumferentially surrounding the first working electrode to define a reaction pool within the second working electrode having a biological reagent provided in the reaction pool. Upon feeding a liquid sample of a user or patient into the reaction pool, the liquid sample will be well retained in the reaction pool to be reacted with the reagent to produce a signal which is then converted to be a readable data as displayed on a measurement apparatus or meter.

Description

technical field [0001] The present invention relates to a biochemical detection test piece, especially a closed ring-shaped second working electrode, which is framed outside the first working electrode to form a biochemical detection test piece with a reaction pool; the biochemical detection Test strips are used to detect the concentration of specific substances in a sample, such as blood sugar, blood esters, uric acid, etc. Background technique [0002] At present, the blood glucose machine used to analyze blood sugar concentration mainly uses the principle of electrochemical (Amperometric electrochemistry) for testing. When the glucose in the blood sample reacts electrochemically with the biochemical test strip, a signal is output, and the current is converted by the blood glucose machine. It is the corresponding blood glucose concentration value for interpretation by users or medical personnel. [0003] Existing biochemical detection test piece 10, such as figure 1 and ...

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Problems solved by technology

[0005] However, biochemical detection test strips are currently manufactured in batch production, which will cause differences between each batch of test strips, such as the distance between the first and second working electrodes 131a and 132a formed in different batches of printing. , will be slightly different due to different batches, resulting in different volumes of the reaction zone 135, resulting in different measurement results for each batch of products

[0006] In addition, the reaction zone 135 formed between the first and second working electrodes 131a and 132a arranged parallel to each other forms a straight line. In order to obtain relatively stable and accurate measurement results, the specimen and the reaction zone 135 must have a longer distance. However, the longer the reaction contact length, in addition to occupying more space on the biochemical test strip, the required sample volume must also increase, thus causing psychological fear for users when sampling blood samples

[0007] Furthermore, the reaction area 135 has openings 135a at both ends. When blood and other specimens are dropped into the reaction area 135, they will overflow along the openings at both ends of the reaction area 135 and cannot stay in the reaction area 135, which will easily cause errors in detection. , affecting the accuracy of the test results

[0008] In the case of U.S. Patent Publication No. 2004 / 0067166A1, although a channel 114 is surrounded by a spacer layer 112 to limit the flow direction of the sample, this flow channel 114 can only guide the flow direction of the blood sample. After dripping into the inlet of the flow channel 114, it will quickly flow along the flow channel 114 to the rearmost electrode 128 due to capillary phenomenon, and the sample cannot be restricted and retained in the reaction zone 106, and the blood sample passes through the reaction zone 106 quickly. Therefore, it is easy to cause misjudgment of detection; moreover, the reaction area 106 covers the biological reaction substance on an electrode 124, and the sample must pass through the induction area 110 between the two electrodes 126 and 124 at the front end before entering the reaction area. 106 produces an electrochemical reaction, because the front electrode 126 is far away from the reaction area 106, so in addition to providing a large amount of sample collection, it will also affect the accuracy of interpretation

In addition, the spacer layer 112 is usually adhered to the substrate 102 by means of adhesive, and a gap is easily formed between the spacer layer 112 and the substrate 102, and the sample is easily leaked out through the gap, and cannot be reliably confined to the reaction zone 106. inside, and show its shortcomings

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