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Traditional Chinese medicine preparation for treating bacterial vaginitis and preparation method of traditional Chinese medicine preparation

A technology of traditional Chinese medicine preparations and vaginitis, which is applied in the field of traditional Chinese medicine preparations for the treatment of bacterial vaginosis and its preparation, which can solve problems such as inability to adhere to treatment, unacceptable patient acceptance, and large gastrointestinal reactions, so as to achieve less recurrence and less toxic side effects , the exact curative effect

Inactive Publication Date: 2014-12-17
孙霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The most effective treatment is the first choice of oral metronidazole, but due to the large gastrointestinal reactions of oral metronidazole, patients should not accept or cannot adhere to the treatment. In recent years, they tend to use vaginal topical drugs. The effect can also reduce side effects, but there are still some side effects

Method used

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Examples

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preparation example Construction

[0040]The present invention also provides a preparation method of the above-mentioned Chinese medicine preparation, wherein the dosage form of the Chinese medicine preparation is a suppository, and the preparation method comprises the following steps:

[0041] Step 1: Soak the raw materials in water for 45 minutes to 1 hour, heat and boil for 1 to 2 hours, filter, and use the filtrate for later use; add water to the filter residue for a second heating, boil for 40 to 60 minutes, filter, and use the filtrate for later use; add water to the filter residue, Heating and boiling for the third time for 30-40 minutes, filtering; combining the three filtrates together, heating and concentrating to a paste, drying in an oven at 80°C, cooling, and grinding into fine powder.

[0042] Step 2: Take one or more equal proportions of semi-synthetic fatty acid glycerides, lanolin, polyethylene glycol and poloxamer as a base; heat the base at a temperature of 50°C to 60°C Melt, add the fine pow...

Embodiment 1

[0048] Embodiment 1 suppository

[0049] Take 340g of tomb head, 80g of bitter bark, 70g of pine grass, 110g of Polygonum arbuscularis, 180g of Pulsatilla chinensis, 60g of red hat top, 90g of bitter grass, 240g of fennel, 210g of snow mountain forest, 160g of water lilac, 190g of dawanhua , 120g sticky grass, 140g pipmeat, 70g clam grass and 110g lacquer grass;

[0050] Prepare as follows:

[0051] Step 1: Soak the raw materials in water for 1 hour, heat and boil for 2 hours, filter, and use the filtrate for later use; add water to the filter residue and heat for the second time, boil for 60 minutes, filter, and use the filtrate for later use; add water to the filter residue, and heat and boil for the third time for 40 minutes , filtered; the three filtrates were combined, heated and concentrated to a paste, dried in an oven at 80°C, cooled, and ground into a fine powder.

[0052] The second step: Take polyethylene glycol and poloxamer as the matrix at a ratio of 1:1; heat ...

Embodiment 2

[0053] Example 2 Lotion

[0054] Take 310g of tomb head, 60g of bitter bark, 80g of pine grass, 140g of Polygonum arbuscularis, 160g of Pulsatilla chinensis, 70g of red hat top, 80g of bitter grass, 220g of spinach, 240g of snow mountain forest, 180g of water lilac, 160g of dawanhua , 140g sticky grass, 110g pipmeat, 60g clam grass and 140g lacquer grass;

[0055] Prepare as follows:

[0056] Step 1: Mix the raw medicinal materials in proportion, put them into an ultrafine pulverizer and pulverize them into a mixture consisting of micron-sized particles with a volume average particle size of 0.1-10 μm and nano-sized particles with a volume-average particle size of less than 0.1 μm Powder, the powder yield of the mixed powder is at least 95%;

[0057] The second step: in the mixed powder obtained in the first step, add ethanol with an alcohol concentration of 95% relative to the quality of the mixed powder that is 4 times the mass of the mixed powder, stir and dissolve to obt...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating bacterial vaginitis and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following raw materials including patrinia heterophylla, bitter bark, thalicturm foetidum, polygonum caespitosum, pulsatilla chinensis, bearded mallotus leaf, tape grass, galium verum, Japanese pachysandra herb, ludwigia octovalvis, calystegia hederacea, desmodiumgangeticum(L.)DC., alate senna leaf, pilea mollis and sagina japonica. The traditional Chinese medicine preparation has the effect of clearing away heat and toxicity, eliminating dampness, stopping leucorrhea, sterilizing and relieving itching, has the exact curative effect on the bacterial vaginitis, is small in toxic and side effects and ensures that the bacterial vaginitis is not easy to relapse.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating bacterial vaginosis and a preparation method thereof. Background technique [0002] Bacterial vaginosis (BV) is a mixed infection caused by Gardnerella, various anaerobic bacteria and mycoplasma due to the imbalance of micro-ecological balance in the vagina, and it is easy to recur. It is one of the common diseases in women of childbearing age. Many other adverse outcomes can result. It is closely related to infertility and miscarriage, endometritis, pelvic inflammatory disease and cervical cancer. [0003] BV is characterized by changes in the vaginal environment, that is, the dominant lactobacilli are replaced by a large number of pathogenic anaerobic bacteria, so metronidrone, which is effective against anaerobic bacteria, is usually used for clinical treatment. The...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P31/04A61P15/02
Inventor 孙霞
Owner 孙霞