A strain of selenium-enriched Cordyceps militaris and its application

Abstract

The invention belongs to the field of microbial fungi, and relates to a selenium-rich cordyceps militaris strain CM001; the wild cordyceps militaris strain which is newly separated in the nature is selected as an original strain; the original strain is subjected to ultraviolet mutation, and the strain can be obtained by separating and screening; the selenium-rich cordyceps militaris strain is preserved in China General Microbiological Culture Collection Center (CGMCC) on July 18, 2014 with the preservation registration number of CGMCC No.9460, is named as CM001 and is named as cordyceps militaris in a classified way. Under the artificial culture conditions, the cordyceps militaris strain has the tolerance for high-concentration selenium, and can carry out biotransformation in a body; the hyphae yeast, the growth matrix or the sporocarp of the selenium-rich cordyceps militaris strain can be used as raw materials of medicines, foods and drinks, or can be prepared into powder, tablets, freeze-drying powder, capsules or electuary.

Description

technical field [0001] The invention belongs to the field of microbial fungi, and relates to a selenium-enriched Cordyceps militaris strain and application thereof. Background technique [0002] Selenium is an essential trace element for the human body, which can remove free radicals in the body, effectively prevent the damage of free radicals to cells, and enhance the body's immunity. The Chinese Nutrition Society lists selenium as one of the 15 daily dietary nutrients, and each person should consume 50-250 micrograms of selenium per day. Moreover, studies have found that daily intake of 200-400 micrograms of selenium can also inhibit tumors. Therefore, selenium is called "the king of anti-cancer" and is an internationally recognized anti-cancer agent. In 2003, the U.S. Food and Drug Administration (FDA) stated: "Selenium can reduce the risk of cancer" and "Selenium can produce anti-cancer effects in the human body", and recognized selenium as a tumor suppressor, and allow...

AI Technical Summary

Problems solved by technology

After the selenium in fungi is transformed in the body, most of it exists in the form of organic selenium, such as selenium polysaccharides and selenoproteins. It has high antioxidant and biological activity, and is very easy to absorb and utilize by the human body. It can be used as the best food for selenium supplementation , but the selenium content in the fruiting bodies of common Cordyceps militaris is low, about 0.1-20mg / kg, and its tolerance to selenium and biotransformation rate are low. In the medium with selenium concentration> 20mg / kg, bacteria The growth of silk and fruiting bodies are severely inhibited, even dead

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