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Contrast agent for detecting gastrointestinal diseases by ultrasonic wave and preparation method thereof

A technology for gastrointestinal diseases and ultrasound detection, applied in the direction of echo/ultrasound imaging agents, etc., can solve problems such as the impact of ultrasound and ultrasound contrast agent market growth, and achieve the effects of no toxic side effects, convenient use, and clear images

Inactive Publication Date: 2015-03-25
王鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If these market regulatory hurdles are cleared, it will have a significant impact on the market growth of ultrasound and ultrasound contrast media

Method used

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  • Contrast agent for detecting gastrointestinal diseases by ultrasonic wave and preparation method thereof
  • Contrast agent for detecting gastrointestinal diseases by ultrasonic wave and preparation method thereof
  • Contrast agent for detecting gastrointestinal diseases by ultrasonic wave and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 A contrast medium for detecting gastrointestinal diseases by ultrasound, which is prepared from the main raw materials in the following weight ratio (10 g for each part): 3 parts of rock horns, 5 parts of corrugated seeds, 4 parts of Centella asiatica, 10 parts of Divine Comedy, 8 parts of cuttlefish bone, 8 parts of potassium iodide, 5 parts of tragacanth gum, 10 parts of Arabic gum, and 8 parts of silicone oil defoamer.

[0042] The preparation method of the above-mentioned contrast agent, the steps are as follows:

[0043] (1) Beat rock horns, corrugated seeds, and squid bones into fingernail-sized pieces, put them in a suitable container, and heat them in a smokeless fire until they are crispy, take them out and let them cool, crush them, and pass them through an 80-mesh sieve;

[0044] (2) Put Centella asiatica and Divine Comedy in a non-iron container, add warm water at 30°C to soak for 30 minutes, the amount of water is 1 times the amount of Centella As...

Embodiment 2

[0050] Example 2 A contrast agent for detecting gastrointestinal diseases by ultrasound, which is prepared from the following main raw materials in the following weight ratio (5g per part): 9 parts of rock horns, 15 parts of corrugated seeds, 8 parts of Centella asiatica, 20 parts of Divine Comedy, 12 parts of cuttlefish bone, 12 parts of potassium iodide, 10 parts of tragacanth gum, 20 parts of gum arabic, and 16 parts of silicone oil defoamer.

[0051] The preparation method of the above-mentioned contrast agent, the steps are as follows:

[0052] (1) Beat rock horns, corrugated seeds, and squid bones into fingernail-sized pieces, put them in a suitable container, and heat them in a smokeless fire until they are crispy, take them out and let them cool, crush them, and pass them through a 120-mesh sieve;

[0053] (2) Put Centella Asiatica and Divine Comedy in a non-iron container, soak in warm water at 40°C for 50 minutes, the amount of water is 5 times the amount of Centella...

Embodiment 3

[0057] Example 3 A contrast agent for detecting gastrointestinal diseases by ultrasound, which is prepared from the following main raw materials in the following weight ratio (15 g per part): 5 parts of rock horns, 8 parts of corrugated seeds, 5 parts of Centella asiatica, 13 parts of Divine Comedy, 9 parts of cuttlefish bone, 9 parts of potassium iodide, 7 parts of tragacanth gum, 13 parts of Arabic gum, and 10 parts of silicone oil defoamer.

[0058] The preparation method of the above-mentioned contrast agent, the steps are as follows:

[0059] (1) Beat rock horns, corrugated seeds, and squid bones into fingernail-sized pieces, put them in a suitable container, and heat them in a smokeless fire until they are crispy, take them out and let them cool, crush them, and pass them through a 90-mesh sieve;

[0060] (2) Put Centella asiatica and Divine Comedy in a non-iron container, soak in warm water at 33°C for 35 minutes, the amount of water is twice the amount of Centella Asia...

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Abstract

The invention discloses a contrast agent for detecting gastrointestinal diseases by an ultrasonic wave. The contrast agent is prepared from the following main raw materials in parts by weight: 3-9 parts of bharal horn, 5-15 parts of concha arcae, 4-8 parts of centella, 10-20 parts of medicated leaven, 8-12 parts of cuttle bone, 8-12 parts of potassium iodide, 5-10 parts of tragacanth, 10-20 parts of Arabic gum and 8-16 parts of silicone oil defoaming agent. The contrast agent arrives at or passes through the terminal ileum after being orally taken for 30 minutes, as well as is uniform in distribution in the intestinal tracts, ideal in contrast density value, clear in development, artefact-free, and capable of effectively improving the detection rate of the early lesions of the gastrointestinal tracts and the staging accuracy of the malignant tumours of the gastrointestinal tracts. The contrast agent is an ideal ultrasonic examination oral contrast agent for the gastrointestinal tracts, and suitable for clinical popularization and use.

Description

technical field [0001] The invention relates to the technical field of medical ultrasound diagnosis, in particular to a contrast agent for detecting gastrointestinal diseases by ultrasound and a preparation method thereof. Background technique [0002] Gastrointestinal disease refers to the inflammation of the intestinal and gastric mucosa, which can be caused by a variety of factors. With this disease, various symptoms will appear, such as nausea, vomiting, diarrhea, etc., and there may also be severe symptoms such as fever and dehydration. Treat early. [0003] Severe gastroenteritis is most harmful to newborns under 18 months of age. The frequent bouts of diarrhea, which cause dehydration and loss of a certain all-important salt, upset the physiochemical balance and, if left unchecked, may lead to shock. For a healthy person, vomiting and diarrhea several times is just like catching a cold, and there will be no major adverse effects. But if vomiting and diarrhea are ac...

Claims

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Application Information

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IPC IPC(8): A61K49/22
Inventor 王鹏
Owner 王鹏
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