Preparation method of eucommia bark superfine powder

A technology of ultra-fine powder and bark of Eucommia, which is applied to medical preparations containing active ingredients, powder delivery, and pharmaceutical formulations, etc. It can solve the problems of low absorption utilization rate, low utilization rate of medicinal materials, and low yield of active ingredients. , to achieve the effects of high extraction rate and dissolution rate, moderate particle size, and simple preparation process

Inactive Publication Date: 2015-04-08
JINGGANGSHAN UNIVERSITY
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AI Technical Summary

Problems solved by technology

[0003] Traditional Eucommia decoctions, pills, etc. have low absorption and utilization rates, and the yield of active ingredients in conventional extraction methods is also low, and the utilization rate of medicinal materials is not high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Peel the eucommia tree that has grown for 10-20 years, and dry it naturally for 10-20 days at an ambient temperature of 15-30°C, fully dry, and control the moisture content at 3-8%. Under room temperature, use a pulverizer for conventional pulverization, and pass through a 30-100 mesh sieve to obtain ordinary powder (particle size 75-78 μm);

[0020] In the process of ultrafine powder preparation, the particle size of the powder is mainly controlled by adjusting the fan frequency. The fan frequency of the ultrafine pulverizer is set to 40-60Hz, the sampling speed is 2 kg / h, and the output is 1-2 kg / h for pulverization. , collect the powder that flies out from the discharge port, and obtain the ultrafine powder of Eucommia bark.

[0021] (1) Determination of powder particle size

[0022] The particle size of each sample powder was measured by Malvern 2000 laser particle size analyzer, and the particle size frequency distribution diagram and cumulative distribution diagr...

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Abstract

The invention provides a preparation method of eucommia bark superfine powder, and relates to the field of traditional Chinese medicine preparation. The eucommia bark superfine powder disclosed by the invention is prepared from eucommia bark by virtue of a superfine grinding technology. The grain size of the superfine powder is 20-25 microns, the cell-wall breaking ratio is above 75%, the extracting rates of active ingredients, namely chlorogenic acid and pinoresinol diglucoside, are 20% and 18% higher than that of normal powder, and the dissolution rates in water, gastric juice and intestinal juice are significantly higher than that of the normal powder. The preparation method of the superfine powder disclosed by the invention is simple to operate, and the problem in the preparation of the traditional Chinese medicine superfine powder is solved, so that the traditional Chinese medicine superfine powder can be directly applied to preparation, and the superfine powder is broad in application prospect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine pharmacy, in particular to a preparation method of ultrafine powder of eucommia bark. Background technique [0002] Eucommia ulmoides is a plant of Eucommia ulmoides ( Eucommia ulmoides Oliv.) dry bark is a valuable tonic medicinal material in China. Its function cures mainly: invigorating the liver and kidney, strengthening bones and muscles, anti-abortion. For deficiency of liver and kidney, soreness of waist and knees, weakness of muscles and bones, dizziness, hemorrhage during pregnancy, restless fetal movement. Eucommia ulmoides is a precious nourishing medicinal material. Its active ingredients contain not only a large number of known active medicinal ingredients, but also a variety of nutrients. Nutrients are the important material basis for the health care of eucommia. [0003] Traditional Eucommia decoctions, pills, etc. have low absorption and utilization rates, and the yie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46
CPCA61K36/46A61K9/14
Inventor 褚洪标周秋贵熊磊阳李庆耀曾红梁生林梁兆昌黄玉珊
Owner JINGGANGSHAN UNIVERSITY
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