Ceftiofur hydrochloride breast injection for dairy cow in dry period and preparation method thereof
A technology for ceftiofur hydrochloride and breast injection, which is applied in the directions of medical preparations containing active ingredients, pharmaceutical formulations, and emulsion delivery, etc., can solve problems such as short action time, achieve slow drug release, simple production process, The effect of avoiding cross infection
Active Publication Date: 2015-04-29
FEED RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES
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The invention discloses a ceftiofur hydrochloride breast injection for dairy cow in dry period and a preparation method thereof. The injection is prepared from the following raw and auxiliary materials: 2.5-10g of ceftiofur hydrochloride, 0.5-5g of glyceryl monostearate, 0.5-5g of a suspending agent and the balance of vegetable oil which is added until the total amount is 100ml. The preparation method comprises the following steps: mixing a proper amount of vegetable oil and glyceryl monostearate, heating and melting; then adding the suspending agent and ceftiofur hydrochloride, and adding the vegetable oil until total amount; and uniformly grinding to prepare the ceftiofur hydrochloride breast injection. The breast injection has the advantages of low drug release speed, high bioavailability and small irritation to local tissues; each lactation region of each dairy cow is independently administrated, so that cross infection is avoided; the injection is injected through breast and is convenient to use, so that animal stress reaction caused by parenteral administration can be avoided, and convenience is brought to clinical administration; the injection has a remarkable curative effect and extremely high popularization value.
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Property | Measurement | Unit |
Particle size | 5.0 ~ 10.0 | µm |
tensile | MPa | |
Particle size | Pa | |
strength | 10 |
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