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Chinese herbal compound tablet for treating allergic rhinitis and preparation method of Chinese herbal compound

A technology for allergic rhinitis and rhinitis tablets, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., can solve problems such as nephrotoxicity, and achieve the effects of reducing infiltration and reducing histamine content.

Inactive Publication Date: 2015-04-29
THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese patent medicine Xinqin Granules and Xinqin Tablets prepared on the basis of Xinqin Recipe have good curative effect in clinical treatment of allergic rhinitis, but Xinqin Recipe contains Asarum medicinal material, and Asarum contains aristolochic acid , long-term use can cause nephrotoxicity

Method used

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  • Chinese herbal compound tablet for treating allergic rhinitis and preparation method of Chinese herbal compound
  • Chinese herbal compound tablet for treating allergic rhinitis and preparation method of Chinese herbal compound
  • Chinese herbal compound tablet for treating allergic rhinitis and preparation method of Chinese herbal compound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Weigh 240g each of Scutellaria baicalensis, Astragalus membranaceus, Schizonepeta, Angelica dahurica, Xanthium, Guizhi, Shi Cangpu, Atractylodes macrocephala and Fangfeng, add 10 times the amount of water, decoct twice, the first time for 1.5 hours, the second time for 1 hours, combine the decoction liquid, concentrate to a density of 1.1-1.2, and vacuum-dry to obtain the active ingredient extract powder in the preparation. 420 g of the obtained extract powder, 120 g of microcrystalline cellulose sodium, 36 g of sodium carboxymethyl starch, 18 g of povidone, and an appropriate amount of 90% ethanol are granulated, mixed with 6 g of magnesium stearate, and compressed into tablets to obtain 1000 tablets medicine.

Embodiment 2

[0053] The same method of embodiment 1 prepares active ingredient of medicinal extract, prepares 100 tablets according to following prescription: medicinal extract powder 42g, microcrystalline cellulose 12g, sodium carboxymethyl starch 3.6g, sodium carboxymethyl cellulose 1.8g , appropriate amount of 90% ethanol granulation, 0.6g magnesium stearate.

Embodiment 3

[0055] Prepare the active ingredient of the extractum in the same way as in Example 1, prepare 100 tablets according to the following prescription: extract powder 42g, starch 12g, sodium carboxymethyl starch 3.6g, sodium carboxymethylcellulose 1.8g, an amount of 90% Ethanol granulation, 0.6g magnesium stearate.

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PUM

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Abstract

The invention discloses a tablet for treating allergic rhinitis and a preparation method of the tablet. The tablet is prepared from 70% of a traditional Chinese medicine extract effective component and 30% of an excipient, wherein the effective component is a water extract prepared from scutellaria baicalensis, astragalus membranaceus, schizonepeta, radix angelicae dahuricae, fructus xanthii, cassia twig, rhizoma acori graminei, rhizoma atractylodis macrocephalae and divaricate saposhnikovia root which are equal in amount and are used as raw materials; the excipient comprises a filler, a disintegrating agent, a lubricant and a coating auxiliary material; and the specification of the tablet is 0.6g; and five pieces of tablets are taken each time. According to the technical scheme disclosed by the invention, the effect of treating allergic rhinitis can be obtained when potential toxicity is reduced; and the Chinese herbal compound is widely and safely applied to clinical practice.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation, in particular to a compound preparation for treating allergic rhinitis and a preparation method thereof. Background technique [0002] Allergic rhinitis is a common disease in otolaryngology, affecting 30% of the world's population. Clinically, nasal itching, sneezing, runny nose, and nasal congestion are the main manifestations, accompanied by conjunctival congestion, pharyngeal discomfort, and even asthma induction, and may cause anosmia, which has recurrent attacks and is not suitable for radical treatment. The treatment of allergic rhinitis with traditional Chinese medicine has the characteristics of improving the immune function of antibodies and reducing the hypersensitivity state of the body. The Chinese patent medicine Xinqin Granules and Xinqin Tablets prepared on the basis of Xinqin Recipe have good curative effect in clinical treatment of allergic rhinitis, but Xi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P11/02A61P37/08
CPCA61K9/2054A61K9/2059A61K9/2866A61K36/232A61K36/238A61K36/28A61K36/284A61K36/481A61K36/538A61K36/539A61K36/54A61K36/888A61K2236/331A61K2236/39A61K2300/00
Inventor 张蓉唐勤黄林清邢茂江涛胡长鹏雷健
Owner THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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