Extracorporeal perfusion apparatus

A technology of in vitro perfusion and equipment, which can be used in extracellular fluid diseases, alkali metal oxides/hydroxides, inorganic chemistry, etc., and can solve the problem of high mortality of patients
CN104582835AActive Publication Date: 2015-04-29FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
Publication Date
2015-04-29

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Abstract

Sorption agent for treating diseases and conditions associated with an increased concentration of at least one inflammation mediator, preferably cytokine, comprises a porous sorption matrix with a neutral, hydrophobic surface, an average pore size of 11-20 nm and an average particle size of 75-150 mu m. Independent claims are also included for: (1) a sorption device comprising at least one sorption agent; and (2) an extracorporeal perfusion device comprising at least one sorption agent. ACTIVITY : Antibacterial; Immunosuppressive; Hepatotropic; Antiinflammatory; Virucide; Antiarthritic; Antirheumatic; Gastrointestinal-Gen; Antipsoriatic. Test details are described but no results given. MECHANISM OF ACTION : None given.
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Description

technical field

[0001] The present invention relates to an extracorporeal perfusion device comprising an extracorporeal blood flow path for delivering blood, a filtrate flow path for delivering plasma, and a controller, wherein the filtrate flow path is connected to the extracorporeal blood flow path with a filter, Wherein the filter has a sieving coefficient of 5% for substances having a molar mass of 340,000 g / mol (relative molecular mass of 340 kDa), and wherein a consumable substance is arranged in the filtrate flow path, the consumable substance comprising a first carrier, which Has a neutral, hydrophobic surface. Background technique

[0002] Sepsis and associated complications cause considerable morbidity and mortality in humans. In most cases, sepsis is attributable to infection by Gram-negative bacteria, when high endotoxin concentrations reach the body and have systemic effects.

[0003] Endotoxins are lipopolysaccharides (LPS) in the cell walls of Gram-negative ...

Claims

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