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Film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle

A latent mastitis and film-forming technology, applied in the direction of medical preparations with non-active ingredients, active ingredients of artificially synthesized polymer materials, diseases, etc., can solve the problem of inability to continuously prevent pathogenic bacteria infection, inability to continuously protect nipples, and nipples Dry cracking and other problems, to achieve the prevention of dairy cow mammary gland inflammation, good preventive effect, and strong bactericidal effect of drugs

Inactive Publication Date: 2015-05-20
YANGZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Conventional medicated baths only disinfect and sterilize the surface of the nipples, and cannot form a film. The liquid medicine is fluid, difficult to stay on the surface of the nipples, and cannot continue to prevent pathogenic bacteria infection. Moreover, long-term use of this type of medicated bath disinfectant will also cause cracked nipples. Inability to consistently protect the nipple

Method used

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  • Film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle
  • Film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle
  • Film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: formula and preparation method:

[0023] Formula: calculated as follows by mass percentage, polyvinyl alcohol-124 (PVA-124) 5.0%, sodium carboxymethylcellulose (CMC) 0.8%, glycerin 5.0%, Tween-80 1.0%, povidone-iodine 5.5% , and the balance is distilled water. Prepare 1000g film-forming teat dipping agent, take by weighing each formula as follows:

[0024]

[0025] Preparation:

[0026] Dissolution: Take 50g of polyvinyl alcohol-124, add an appropriate amount of distilled water to soak for 48 hours to make it fully swell, then heat it while stirring in a water bath at 95°C to fully dissolve it, and keep it warm for 2-2.5 hours until there are no small particles , to prepare a film-forming material solution.

[0027] Mixing: Take the above film-forming material solution placed at room temperature, put it in a 40°C water bath to preheat, and slowly add Tween-80, glycerin, povidone-iodine and carboxymethyl infiltrated with absolute ethanol while stirri...

Embodiment 2

[0029] Example 2 : udder contrast test

[0030] 1. Grouping of test animals

[0031] A total of 50 lactating dairy cows were randomly selected in a barn, and 20 cows were selected for the experiment in August-September (summer) and 30 cows were selected for experiment in November-December (winter), with a test period of 30 days. The four udders of the selected dairy cows were divided into left and right parts. The left side was treated with film-forming teat dipping agent, which was the test group; the right side was used with conventional disinfectant iodophor, which was the control group. Medication method: After milking, use the dipped nipples of the above two medicinal baths respectively, soak the root of the nipples with the liquid medicine and stay for 30 seconds, twice a day.

[0032] 2. test record

[0033] Milk samples were collected before the test, 7d, 14d, 21d and 30d, and the whole milk analysis was carried out on the milk samples. BMT detection and milk ...

Embodiment 3

[0043] Embodiment 3: group medication effect test

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Abstract

The invention relates to a film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle. The film-forming papilla medicated bath preparation is composed of the following components by mass percent: 5-10% of film-forming material, 5-8% of plasticizer, 0.6-1.0% of fortifier, 1.0-1.4% of surface active agent, 5-10% of antibacterial agent and the balance of solvent. The invention further relates to a preparation method of the film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle. The film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle provided by the invention has a physical barrier function and a drug sterilization function, and is used in medicated bath after daily milking of dairy cattle, and can continuously protect papillas and cut off the infection route of mastitis after sterilization, so as to prevent mastitis, and the medicated bath preparation is green, environmentally friendly, simple, safe and good in preventive effect.

Description

technical field [0001] The invention relates to a veterinary medicinal bathing agent, in particular to a film-forming teat medicinal bathing agent for controlling recessive mastitis of cows. Background technique [0002] Dairy cow mastitis is a common and frequently-occurring disease in dairy cows. As the incidence of dairy cow mastitis, especially recessive mastitis, increases, the somatic cell count (SCC, somatic cell count) in milk increases, which seriously affects the quality of raw milk. Therefore, more and more attention has been paid to the treatment of cow mastitis, and the use of antibiotics, the emergence of drug-resistant strains and drug residues in milk seriously endanger the health of consumers. Use less or no antibiotics to effectively control drug residues and ensure the safety of raw milk It is the main goal of the prevention and control of mastitis in dairy cows. Therefore, the significance of preventing and controlling the occurrence of mastitis in dairy ...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K31/79A61P31/02A61P15/14A61K47/32A61K47/38A61K47/10
Inventor 耿晓晗杨章平张志鹏
Owner YANGZHOU UNIV
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