Film-forming papilla medicated bath preparation used for controlling recessive mastitis of dairy cattle
A latent mastitis and film-forming technology, applied in the direction of medical preparations with non-active ingredients, active ingredients of artificially synthesized polymer materials, diseases, etc., can solve the problem of inability to continuously prevent pathogenic bacteria infection, inability to continuously protect nipples, and nipples Dry cracking and other problems, to achieve the prevention of dairy cow mammary gland inflammation, good preventive effect, and strong bactericidal effect of drugs
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Embodiment 1
[0022] Embodiment 1: formula and preparation method:
[0023] Formula: calculated as follows by mass percentage, polyvinyl alcohol-124 (PVA-124) 5.0%, sodium carboxymethylcellulose (CMC) 0.8%, glycerin 5.0%, Tween-80 1.0%, povidone-iodine 5.5% , and the balance is distilled water. Prepare 1000g film-forming teat dipping agent, take by weighing each formula as follows:
[0024]
[0025] Preparation:
[0026] Dissolution: Take 50g of polyvinyl alcohol-124, add an appropriate amount of distilled water to soak for 48 hours to make it fully swell, then heat it while stirring in a water bath at 95°C to fully dissolve it, and keep it warm for 2-2.5 hours until there are no small particles , to prepare a film-forming material solution.
[0027] Mixing: Take the above film-forming material solution placed at room temperature, put it in a 40°C water bath to preheat, and slowly add Tween-80, glycerin, povidone-iodine and carboxymethyl infiltrated with absolute ethanol while stirri...
Embodiment 2
[0029] Example 2 : udder contrast test
[0030] 1. Grouping of test animals
[0031] A total of 50 lactating dairy cows were randomly selected in a barn, and 20 cows were selected for the experiment in August-September (summer) and 30 cows were selected for experiment in November-December (winter), with a test period of 30 days. The four udders of the selected dairy cows were divided into left and right parts. The left side was treated with film-forming teat dipping agent, which was the test group; the right side was used with conventional disinfectant iodophor, which was the control group. Medication method: After milking, use the dipped nipples of the above two medicinal baths respectively, soak the root of the nipples with the liquid medicine and stay for 30 seconds, twice a day.
[0032] 2. test record
[0033] Milk samples were collected before the test, 7d, 14d, 21d and 30d, and the whole milk analysis was carried out on the milk samples. BMT detection and milk ...
Embodiment 3
[0043] Embodiment 3: group medication effect test
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