In-situ preparation method of nanofiber antibacterial dressing

Abstract

The invention discloses an in-situ preparation method of a nanofiber antibacterial dressing and belongs to the field of medical dressing. According to the method, a nanofiber antibacterial dressing containing a silver-supported nano particle is electrically spun directly on a wound surface by virtue of handheld electrostatic spinning equipment, wherein the high polymer material for electric spinning is a water-soluble or degradable biocompatibility material; the solvent is a medical solvent, and is safe and effective when directly sprayed on the wound surface; the used silver-supported nano particle is the nano particle with nano silver particles or silver ions adsorbed and loaded on the surface. By virtue of a doping manner, the antibacterial effect of the nano silver particles or silver ions is reserved; the problems of oxidation and agglomeration of silver nano particles are effectively overcome; the preparation method disclosed by the invention is simple and convenient to operate, is not limited by an operation site, and can be applied to acute trauma emergency treatment on various occasions; and the obtained dressing is stable in antibacterial property, does not need to be fixed extra, and is applicable to wound surfaces with various shapes, depths and sizes on different parts.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a method for rapidly preparing nanofiber antibacterial dressings in situ. Background technique [0002] With the rapid development of transportation, construction, and modern industry, traumas caused by various accidents are increasing, among which acute trauma is the most common. Acute trauma mainly has problems such as high infection rate, slow wound healing, and complex wounds that are easily affected by the environment. Improper wound treatment can easily cause infection, affect the recovery of the wound, and pose a threat to the health of the wounded. In severe cases, it may even be life-threatening. . Traditional medical dressings such as gauze, bandages, absorbent cotton, etc. have the following disadvantages: 1) The dressing covers the surface of the wound and can only play a limited role as a protective barrier to avoid external sources of infection (dust, microorganism...

AI Technical Summary

Problems solved by technology

Acute trauma mainly has problems such as high infection rate, slow wound healing, and complex wounds that are easily affected by the environment. Improper wound treatment can easily cause infection, affect the recovery of the wound, and pose a threat to the health of the wounded. In severe cases, it may even be life-threatening.

Traditional medical dressings such as gauze, bandages, absorbent cotton, etc. have the following disadvantages: 1) The dressing covers the surface of the wound and can only play a limited role as a protective barrier to avoid infection caused by contact between external sources of infection (dust, microorganisms, etc.) and the wound

However, most nanofiber dressings are degradable materials or are loaded with special functional components, which have strict requirements on storage conditions and are not suitable for long-term storage. This kind of dressing is also not easy to fix when used, and it is not easy to get along with the uneven surface. The technical flaw of the wound surface fit perfectly

This defect in storage and use limits the application of this type of material in harsh conditions and emergencies.

The current technical means lack effective, fast and convenient treatment methods for sudden acute wounds in battlefields and traffic accidents, which restricts the application of nanofiber dressings in emergency medicine.

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