Pharmaceutical composition for treating gallstones

A composition and drug technology, which can be used in drug combinations, pharmaceutical formulations, plant raw materials, etc., to solve problems such as the impact of the digestive system of surgical patients

Inactive Publication Date: 2015-06-10
班晓杰 +4
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine mainly treats gallstones through surgery, but the removal of the gallbladder will have a great impact on the digestive system of the surgical patient

Method used

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  • Pharmaceutical composition for treating gallstones

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Example 1 Clematis 30g, Gynostemma pentaphyllum 30g, Ume 30g, Citrus aurantium 25g, Qingpi 25g, Forsythia 25g, Capillary wormwood 25g, Gardenia 20g, Atractylodes macrocephala 20g, Gallus gallis 20g, Desmodium 20g

[0038] The preparation method of the granules of the present invention: take the raw materials of the above pharmaceutical composition and mix them evenly, pulverize them into 10-20 mesh coarse particles, add 6 times (volume) of 60% ethanol, extract three times continuously at 60° C. with microwave extraction method, and extract the Centrifuge, concentrate the net extract to a thick paste with a relative density of 1.20-1.30, vacuum dry, crush the dry paste, add 800g of compressible starch, 450g of sodium carboxymethyl cellulose, mix well and pass through an 80-mesh sieve, add appropriate amount of water Granulate, dry under reduced pressure at 60°C, granulate, pack into 100 bags, and obtain.

Embodiment 2

[0039] Example 2 Clematis 30g, Gynostemma pentaphyllum 30g, Ume 30g, Citrus aurantium 25g, Qingpi 25g, Forsythia 25g, Capillary wormwood 25g, Gardenia 20g, Atractylodes macrocephala 20g, Gallus gallis 20g, Desmodium 20g

[0040] The preparation method of the hard capsule of the present invention: take the raw material drug of the above pharmaceutical composition and mix, pulverize into 10-20 mesh coarse particles, add 6 times (volume) of 60% ethanol, extract three times continuously at 60 ° C with the microwave extraction method, and extract the liquid Centrifuge, concentrate the net infusion to a thick paste with a relative density of 1.20-1.30, dry in vacuum, crush the dry paste, put it into capsules, and obtain.

Embodiment 3

[0041] Example 3 Clematis 30g, Gynostemma pentaphyllum 30g, Ume 30g, Citrus aurantium 25g, Qingpi 25g, Forsythia 25g, Capillary wormwood 25g, Gardenia 20g, Atractylodes macrocephala 20g, Gallus gallis 20g, Desmodium 20g

[0042] The preparation method of the tablet of the present invention: take the raw materials of the above pharmaceutical composition and mix them evenly, pulverize them into 10-20 mesh coarse particles, add 6 times (volume) of 60% ethanol, extract three times continuously at 60° C. with the microwave extraction method, and extract the liquid Centrifuge, concentrate the net infusion to a thick paste with a relative density of 1.20-1.30, vacuum-dry, crush the dry paste, add appropriate amount of starch, talcum powder and magnesium stearate, granulate, compress into tablets, and coat.

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Abstract

The invention relates to a pharmaceutical composition for treating gallstones. The pharmaceutical composition for treating gallstones is composed of radix clematidis, gynostemma pentaphyllum, smoked plums, fructus aurantii immaturus, pericarpium citri reticulatae viride, fructus forsythiae, oriental wormwood, gardenia, atractylodes macrocephala koidz, endothelium corneum gigeriae galli and christina loosestrife herb. The pharmaceutical composition for treating gallstones promotes the movement function of a gall bladder and performs a preventive and therapeutic effect on gallstones, and relates to activation of an inositol lipid IP3 / Ca2+ signal transduction system, increase of released Ca2+ in gall bladder smooth muscle cells and promotion of shrinkage of the gall bladder, and the purpose of treating gallstones is achieved.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating gallstones. Background technique [0002] Gallstone is a relatively common disease, but its pathogenesis has not been fully elucidated. Especially in recent years the incidence rate is on the rise, causing harm to people's health. Gallstones are mostly divided into biliary stones, gallbladder stones and so on. At present, it is believed that most gallstones are caused by poor excretion caused by stagnation of qi in the liver and gallbladder, damp-heat in the biliary tract, stagnation of qi in the liver and obstruction of the biliary tract, etc., leading to the occurrence of gallstones. Modern medicine mainly treats gallstones through surgery, but the removal of the gallbladder will have a great impact on the digestive system of the surgical patient. The treatment of gallstones by traditional Chinese medicine has a long history, and it ha...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P1/16A61K35/57
Inventor班晓杰任海滨曲伟强张越谢振堂
Owner班晓杰