Check patentability & draft patents in minutes with Patsnap Eureka AI!

SiO2 coated luminescent quantum dot composite particle and preparation method thereof

A technology of composite particles and luminescent quantum, which is applied in the direction of luminescent materials, chemical instruments and methods, etc., can solve the problems such as the reduction of luminous efficiency of quantum dots, and achieve the effects of high stability, water solubility, non-toxicity, and low biological toxicity

Active Publication Date: 2015-08-19
济南德亨医学科技有限公司
View PDF6 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

SiO 2 The layer is quantum dots, which can provide quantum dots with good biological adaptability and good stability. Usually SiO 2 Coating is to complete the ligand exchange first, such as using mercapto-containing silane reagents to replace the ligands on the surface of quantum dots, and then complete the SiO 2 Coating, this method leads to a reduction in the luminous efficiency of quantum dots. In view of this, it is necessary to develop a SiO with a simple preparation method, high luminous efficiency and high stability. 2 Coated composite particles have good application prospects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • SiO2 coated luminescent quantum dot composite particle and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 1.1 Synthesis of CdSe quantum dots by organic method (see J. Phys. Chem. C, 2010, 114, 6205-6215 for details): firstly, 500 mg of cadmium oxide, 2 g of dioctylamine and 2 g of nonanoic acid were mixed in three Mix in the neck flask, keep vacuum at 100°C for 15min, then heat to 200°C under nitrogen protection to dissolve cadmium oxide, then lower it to 120°C, and quickly inject 10 g of selenium trioctylphosphine (TOP) solution (the mass of selenium Concentration is 10%), in order to control the luminous color, the growth time is 10 min, the CdSe quantum dots are separated, washed, and then dispersed in toluene solution to obtain CdSe quantum dot toluene solution, the concentration is 0.01 mg / mL.

[0025] 1.2 Coating ZnS shell on the surface of CdSe quantum dots (see J. Phys. Chem. C, 2010, 114, 6205-6215 for details): Step 1) Prepare 4 mL of CdSe quantum dot toluene solution, 2 g of dioctylamine and 0.05 g of dimethyl zinc (dissolved in 2 mL of TOP) was mixed, then heate...

Embodiment 2

[0030] 2.1 Synthesize CdTe quantum dots by organic method, using a known method (see J. Phys. Chem. C, 2010, 114, 6205-6215 for details): first, cadmium oxide 500 mg, dioctylamine 2 g Mix with 2 g nonanoic acid in a three-neck flask, keep vacuum at 100 °C for 15 min, heat to 200 °C under nitrogen protection to dissolve cadmium oxide, then lower it to 130 °C, put 10 g tellurium TOP solution (the mass of tellurium Concentration of 12%) was injected rapidly, in order to control the luminescent color, the growth time was 1 h, the CdTe quantum dots were separated, washed, and then dispersed in toluene solution to obtain CdTe quantum dot toluene solution with a concentration of 0.01 mg / mL.

[0031] 2.2 Coating ZnS shell on the surface of CdTe quantum dots: freshly prepared CdTe quantum dots toluene solution 4 mL (quantum dot concentration 0.01 mg / mL), dioctylamine 2 g, and 0.05 g dimethyl zinc (dissolved to 2 mL TOP) mixed, then heated to 60 °C, and 10 g of sulfur in TOP solution (t...

Embodiment 3

[0034] 3.1 The preparation method of CdTe quantum dots synthesized in organic phase is the same as that in Example 2.1. Obtain the toluene solution of CdTe quantum dots, the dispersion concentration is 10 -5 mol / L, and then exchange ligands on the surface of quantum dots with oleic acid, that is, add 2 mL of oleic acid to the toluene solution of quantum dots, stir for 12 h, and obtain a quantum dot dispersion coated with oleic acid ligand layer.

[0035] 3.2 Coating SiO with microemulsion method 2 Layer: Add 1.5mL of polyoxyethylene (5) nonylphenyl ether to 20mL of cyclohexane, mix, add 1mL of water and stir to obtain a microemulsion, and then add the quantum Add 2 mL of dispersion liquid, stir evenly, add 0.1 mL of ammonia water with a mass concentration of 6.75% and 2 μL of propyl orthosilicate, stir for 5 h, centrifuge and wash to obtain SiO 2 SiO with a layer thickness of 5 nm 2 Coated luminescent quantum dot composite particles. The luminous efficiency of this composi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
thicknessaaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a SiO2 coated luminescent quantum dot composite particle. The composite particle adopts a quantum dot as a core, the quantum dot is coated with an oleic acid ligand layer, and the oleic acid ligand layer is coated with a SiO2 shell layer; and the diameter of the composite particle is 15-55nm, the oleic acid ligand layer is a monomolecular layer, and the thickness of the SiO2 shell layer is 5-20nm. The invention also discloses a preparation method of the luminescent quantum dot composite particle. A SiO2 layer is directly coated on the oleic acid ligand modified quantum dot through a microemulsion process by adopting a sol-gel technology, and ligand exchange is not needed in the preparation process, so the influence on the surface properties of the quantum dot is reduced, and the oleic acid ligand layer on the surface of the quantum dot is reserved; and the SiO2 coated luminescent quantum dot composite particle prepared in the invention has the characteristics of high luminescence efficiency, high hydrophilicity, high stability, low biological toxicity and very good application prospect.

Description

technical field [0001] The invention belongs to the field of functions and biomaterials, and relates to a SiO 2 Coated luminescent quantum dot composite particle and preparation method thereof. Background technique [0002] Since the research on quantum dots used in fluorescent probes was reported in the American Journal of Science in 1998, the research on quantum dots has attracted much attention. Quantum dots have been widely used in fluorescent probes, light-emitting devices and other fields. The luminous efficiency of quantum dots It is a key indicator that directly affects the application of quantum dots. Usually, quantum dots with high luminous efficiency are synthesized in organic solutions, and the water phase conversion needs to be completed during the application process. Water-soluble quantum dots can be widely used in biological detection systems, especially for the research of various fluorescent probes for tracking. Quantum dots with high luminous brightness,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C09K11/88C09K11/70C09K11/56C09K11/02
Inventor 杨萍陈玲杜莹莹朱元娜
Owner 济南德亨医学科技有限公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com