System for detecting Helicobacter pylori infection

A technology of Helicobacter pylori and detection unit, applied in the field of detection of Helicobacter pylori infection and detection system of Helicobacter pylori infection, which can solve the problems of reducing the missed diagnosis rate, high specificity, harsh conditions, etc., and achieve shortened detection cycle and high accuracy , the effect of improving the accuracy

Inactive Publication Date: 2015-10-07
李昌伟
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

For pathological biopsy of gastric mucosa, patients need to endure the pain of inserting a mirror. If Helicobacter pylori is focally distributed, it will easily lead to missed diagnosis (missed diagnosis rate is 10%), but the doctor's rich operating experience and correct sampling can reduce the missed diagnosis rate.
Bacterial culture method is a good method with high specificity, strong sensitivity, low technical equipment requirements, and low price, but the conditions are hars...

Method used

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  • System for detecting Helicobacter pylori infection
  • System for detecting Helicobacter pylori infection

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Embodiment Construction

[0022] See attached figure 1 and 2 It is an embodiment of a system for detecting Helicobacter pylori infection of the present invention, including a laser output unit 1, a frequency locking unit 2, a detection unit 3, a display unit 4, a semiconductor laser 5, a laser temperature controller 6, and a laser current controller 7 , optical fiber beam splitter 8, PID servo system 9, sample cell 10, input flange 11, photodetector 12, lock-in amplifier 13, air outlet pipe 14, focusing lens 15, photodetector 2 16, white cell 17. Three spherical mirrors with the same focal length 18, field mirror 18 (1), retroreflector 18 (2), retroreflector 2 18 (3), gas circuit control unit 19, lock-in amplifier 220, computer 21. Alarm 22, sensor 23, solenoid valve one 24, nitrogen cylinder 25, solenoid valve two 26, negative pressure pump 27, intake valve 28, control module 29.

[0023] Such as figure 1 In the shown detection system for Helicobacter pylori infection, the laser output unit 1 inclu...

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Abstract

The invention discloses a system for detecting Helicobacter pylori. The system comprises a laser output unit, a frequency locking unit, a detection unit, an air channel control unit and a display unit. The output wavelength of a semiconductor laser is adjusted by a laser temperature controller and a laser current controller, output laser is divided by a fiber splitter to form two beams, one beam of laser is input to the frequency locking unit to stabilize the wavelength in an absorption peak position, the other beam of laser enters the detection unit, the detection unit is provided with a white cell device in order to effectively increase the length of a light path and improve the detection sensitivity, a signal obtained by the detection unit is transmitted to the display unit, and an alarm gives an alarm when the <13>CO2 concentration of the display unit exceeds a preset concentration value in order to fast detect the existence of Helicobacter pylori in the stomach of a patient. The system effectively improves the detection sensitivity, allows the real-time detection sensitivity to be in ppm magnitude, greatly shortens the detection cycle, improves the detection accuracy, increases the stability, reduces the detection cost, and effectively meets application demands of medical detection.

Description

technical field [0001] The invention relates to the technical field of medical instruments and equipment, and relates to a system for detecting Helicobacter pylori infection, in particular to detecting Helicobacter pylori infection by using wavelength modulation technology in Tunable Semiconductor Laser Absorption Spectroscopy (TDLAS) technology. Background technique [0002] Helicobacter pylori has been identified as the main pathogenic factor of chronic gastritis and peptic ulcer. Helicobacter pylori infection can cause gastric mucosal congestion, edema, and even erosion and ulcers, and is closely related to gastric cancer. More than 41% of the population in the world has been infected with Helicobacter pylori, and even 58.07% in developing countries. 10-20 years old infection has reached more than 50%. There are 400,000 new gastric cancer patients in China every year, accounting for 42% of the world's incidence. It is worth noting that the rate of gastric cancer patient...

Claims

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Application Information

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IPC IPC(8): G01N21/39
Inventor 王振基张伟宏冯小娟刘敏杰李昌伟
Owner 李昌伟
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