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Medicine for treating children's intussusception and preparation method of medicine

An intussusception and drug technology, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of treating the symptoms but not the root cause, large side effects, and unfavorable treatment, and achieves precise curative effect, fast onset, The effect of a short course of treatment

Inactive Publication Date: 2015-10-14
李娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] But above-mentioned therapeutic method treats the symptoms but not the root cause, is unfavorable for treatment, and recurs easily, and side effect is big

Method used

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  • Medicine for treating children's intussusception and preparation method of medicine
  • Medicine for treating children's intussusception and preparation method of medicine

Examples

Experimental program
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Effect test

preparation example Construction

[0068] When the dosage form of the medicine is a granule, its preparation method may comprise the following steps:

[0069] The first step is to mix the various raw materials of the drug according to the stated ratio, add ethanol with an alcohol concentration of 4 to 8 times that of the mixture, and heat it to boiling and reflux for 3 to 5 hours, filter, and use osmotic Slowly percolate at a speed of 1-2ml per minute by roller method, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, and spray dry , the air inlet temperature of the spray dryer is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry paste powder;

[0070] In the second step, 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin are added to the obtained dry paste powder to form granules, and dried at 40-50° C. to obtain granules.

[0071] When the dosage for...

Embodiment 1

[0079] Example 1 Granules

[0080] The preparation process of the granules of the present invention is as follows: get 160g Polygonatum Polygonatum, 280g Li Nutren, 150g Persimmon Frost, 220g Brome, 300g Sagittarius, 340g Cistanche, 200g Asparagus, 300g Hemp Seed, 230g Purslane, and red chopsticks 400g, pandanus 200g, limonium 440g, cow's ear rhubarb 320g, copper coin ephedra 180g, Cynomorium 150g, shenjincao 320g, Xu Changqing 240g, nard pine 200g, blood potato 320g and Geshanxiao 140g;

[0081] The first step is to mix the raw materials of the medicine according to the stated ratio, add 90% ethanol with an alcohol concentration 7 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and use the percolation method at 2 ml per minute. Slowly percolate, collect the percolate, then concentrate under reduced pressure at a vacuum of 0.07Mpa to a paste with a relative density of 1.07 at 55°C, spray dry, the air inlet temperature of the spray dryer is 175°C, and...

Embodiment 2

[0083] Example 2 tablet

[0084] The preparation process of tablet of the present invention is: get Polygonatum Polygonatum 140g, Li Nutren 320g, Persimmon Shuang 240g, Brome 150g, Sagittarius 220g, Cistanche 350g, Asparagus 200g, Hempen 300g, Purslane 240g, red chopsticks 340g, 220g of pandanus, 420g of limonium, 260g of rhubarb, 220g of copper coin ephedra, 140g of Cynomorium, 320g of Shenjincao, 240g of Xu Changqing, 170g of sweet pine, 330g of blood-boosting potato and 150g of Geshanxiao;

[0085] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 85% that is three times the mass of the mixture, heat and reflux for 5 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and the second extr...

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Abstract

The invention discloses a medicine for treating children's intussusception and a preparation method of the medicine. The medicine is prepared from the following raw herbal materials: radix polygonati officinalis, plum seeds, persimmon frost, bromegrass, rhizome of spiny lasia spinyelephantsear, cistanche, radix asparagi, seeds of Amygdalus communis L. fructus cannabis, Castanea mollissima Bl., purslane, great willowherb herb, root of thatch screwpine, gmelin sealavender herb, pinecone, root of Tibet goldenray, rumex crispus, Shuteria sinensis Hemsl., cynomorium songaricum, lycopodium clavatum, paniculate swallowwort root, rhizoma nardostachyos, Dioscorea esquirolii Prain et Burkill, australian cowplant root or leaf, girald pteroxygonum root and geranium strictipe. The medicine has the efficacies of moistening the dryness and lubricating the intestines, relieving the pain and obstruction, as well as the efficacy of boosting gastrointestinal propulsive motility, and has the advantages of rapid effect, high effective rate, definite curative effect, short treatment course, no side or toxic side, low cost and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating intussusception in children and a preparation method thereof. Background technique [0002] Intussusception (intussusception) is a common acute abdomen in infants and young children in which the proximal intestinal segment and its mesentery are invaginated into the distal intestinal cavity, resulting in intestinal obstruction. It is more common in obese and healthy infants and young children under 2 years old. Intussusception can cause abdominal cramps. It is manifested as obvious irritability and discomfort in children who were originally quiet, and may have general rigidity. The legs are bent towards the abdomen, the expression is painful, and the symptoms suddenly stop; the baby who cannot express has paroxysmal crying, and the performance is normal between attacks or falls asleep quietly. As the disease progresses, intermittent abd...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P1/00
Inventor 李娟
Owner 李娟
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