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Medicine for treating immune male infertility

A male infertility and immune technology, applied in the field of traditional Chinese medicine, can solve the problems of patient harm economy, limited curative effect, loss, etc., achieve remarkable curative effect, improve immune function, eliminate hypersensitivity and autoimmune reactions

Inactive Publication Date: 2015-11-25
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the etiology of immune male infertility is clear, the exact mechanism has not been elucidated, and the curative effect of the treatment is limited; in addition, because some people blindly exaggerate the effect of certain drug treatments in order to obtain illegal benefits, coupled with the great enthusiasm of patients for treatment, Serious situation of drug abuse in the treatment of this disease, causing direct harm to patients and causing huge economic losses

Method used

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  • Medicine for treating immune male infertility

Examples

Experimental program
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Effect test

preparation example Construction

[0053] The present invention also provides a preparation method of the above-mentioned drug granules, which includes:

[0054] The first step is to weigh Epimedium, Cornus officinalis, Cuscuta, Acanthopanax, Parasitic Huang, Codonopsis, Cistanche, Lemongrass, Hengjingxi, Dendrobium, Antler, Polygonatum and Lycium barbarum according to the aforementioned ratio, water extraction, and purification , to obtain the first raw drug powder;

[0055] In the second step, the remaining raw material drug components are extracted by ethanol percolation to obtain the second raw material drug powder;

[0056] The third step is to mix the first raw drug powder and the second raw drug powder, add 0.4-0.6 times the sucrose powder and 0.1-0.3 times the dextrin of the mixed drug powder, make granules, and dry at 40-50 ° C to obtain Granules.

[0057] The first step is further specifically, according to the aforementioned ratio, call Epimedium, Cornus officinalis, Cuscuta, Acanthopanax, Parasiti...

Embodiment 1

[0060] Example 1 Particle 1

[0061] Weigh 40g Epimedium, 30g Cornus officinalis, 35g Dodder, 40g Acanthopanax, 20g Parasitic Huang, 35g Codonopsis, 30g Cistanche, 15g Lemongrass, 15g Hengjingxie, 20g Dendrobium, 40g Antler, 40g Polygonatum and 30g Lycium barbarum Separately crushed into coarse powder, mixed together, extracted with water, add 2.5kg of water for the first time, soak for 2 hours, decoct for 3 hours; add 1.6kg of water for the second time, soak for 1 hour, decoct for 2 hours, combine the decoction, filter, Combine the extracts, recover ethanol under reduced pressure and concentrate until the concentration of the drug solution is 0.4g crude drug / mL. After suction filtration, the relative density of the filtrate is about 1.06 at 20°C; Elute with deionized water or distilled water 10 times the volume of the resin column, and then elute with 95% ethanol 5 times the volume of the resin column, collect the ethanol eluate, remove the solvent, and obtain the first raw d...

Embodiment 2

[0062] Example 2 Particle 2

[0063] Weigh 38g of Epimedium, 28g of Cornus officinalis, 33g of Dodder, 38g of Acanthopanax, 18g of Parasitic Huang, 33g of Codonopsis, 28g of Cistanche, 13g of Lemongrass, 13g of Hengjingxi, 18g of Dendrobium, 38g of Antler, 38g of Polygonatum and 28g of Lycium barbarum Separately crushed into coarse powder, mixed together, extracted with water, add 2kg of water for the first time, soak for 2h, decoct for 3h; add 1.5kg of water for the second time, soak for 1h, decoct for 2h, combine the decoction, filter, combine For the extract, ethanol was recovered under reduced pressure and concentrated until the concentration of the drug solution was 0.4g crude drug / mL. After suction filtration, the relative density of the filtrate was about 1.06 at 20°C; Elution with deionized water or distilled water 10 times the volume of the resin column, and then elution with 95% ethanol 5 times the volume of the resin column, collect the ethanol eluate, remove the so...

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Abstract

The invention provides medicine for treating immune male infertility. The medicine comprises herba epimedii, cornus officinalis, semen cuscutae, acanthopanax roots, involucrate balanophora, oldenlandia diffusa, herba leonuri, radix codonopsis, prepared rehmannia roots, fructus gardeniae, herba cistanches, herba picriae, angelica sinensis, lemongrass herbs, membranaceous beautyleaf roots, bulbophyllum inconspicuum maxim, herba hyperici sampsonii, herba taxilli, cornu cervi pantotrichum, semen euryales, rhizoma polygonatum, fructus lycii and fructus aurantii immaturus. According to the medicine, the treatment effect is significant, the weakened immune functions of a patient can be improved, and harmful hypersensitivity and autoimmune response can be eliminated.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating immune male infertility. Background technique [0002] Male infertility has always been a problem that plagues mankind. According to WHO statistics, 5% to 8% of couples of childbearing age in developed countries may have infertility problems, and about 50% of the infertility factors involve men. The incidence of male infertility diagnosis and classification in my country is 1.35%. Although the etiology of immune male infertility is clear, the exact mechanism has not been elucidated, and the curative effect of treatment is limited; in addition, because some people blindly exaggerate the effect of certain drug treatments in order to obtain illegal benefits, coupled with the great enthusiasm of patients for treatment, The serious situation of drug abuse in the treatment of this disease brings direct harm to patients and causes huge econo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61P15/08A61P37/04
Inventor 不公告发明人
Owner QINGDAO HUAREN TECH INCUBATOR
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